Results 151 to 160 of about 156,575 (279)
ABSTRACT Recombinant adeno‐associated viruses (AAVs) have become a leading platform for in vivo gene therapy. The AAV capsid is assembled from 60 individual protein subunits derived from three overlapping viral proteins (VPs): VP1, VP2, and VP3. The VP's ratio distribution affects the capsid trafficking and transgene expression.
Yiran Li +10 more
wiley +1 more source
Modeling Airborne Influenza in Three Dimensions
A novel 3D fluid dynamics model demonstrates how influenza outbreaks spread spatially via “epidemic flow.” Simulations reveal that direct contact is the dominant transmission route over aerosol spread, offering a new tool to inform targeted public health interventions and spatially‐aware risk assessment.
Daniel Ugochukwu Nnaji +4 more
wiley +1 more source
Corrigendum: RF_phage virion: classification of phage virion proteins with a random forest model
Yanqin Zhang, Zhiyuan Li
doaj +1 more source
Evolution of H5N1 Cross‐Species Transmission: Adaptive Mutations Driving Avian‐to‐Human Infection
This review synthesizes current knowledge on the molecular mechanisms underpinning H5N1's host adaptation, focusing on key mutations in viral proteins. Critical mutations are discussed in detail, highlighting their roles in altering receptor specificity, promoting antiviral resistance, and expanding viral tropism. The review underscores the urgent need
Wenxin Man +7 more
wiley +1 more source
Aptamer‐Based Approaches for Influenza Virus Detection: A Systematic Review
ABSTRACT Background and Aims Influenza remains a globally prevalent respiratory infection that is challenging to diagnose accurately. This systematic review focuses on aptamer‐based tools for influenza virus detection, aiming to overcome the limitations of traditional diagnostic methods.
Javad Charostad +6 more
wiley +1 more source
Clinical progress note: Hepatitis A virus
Visual Abstract Abstract Despite a decline in hepatitis A virus (HAV) incidence following vaccine introduction, HAV remains a public health concern in the United States. Recent multi‐state outbreaks have demonstrated that HAV can re‐emerge and highlight inequities in vaccine coverage or access, outbreak response, and in those with social or health risk
James M. McCluskey III +2 more
wiley +1 more source
Bacteriophage Therapy: Current Strategies and Future Perspectives
This manuscript systematically reviews the expanding scope of phage applications. It moves beyond traditional antibacterial use to explore their role in precision therapies against drug‐resistant infections, their synergy with antibiotics, and advanced biomaterial‐assisted delivery systems.
Zihe Zhou +7 more
wiley +1 more source
Viral evolution during primary infection in immunocompromised hosts. [PDF]
Craig M, Deng X, McLeod DV.
europepmc +1 more source
This review focuses on the clinical features, molecular mechanisms, treatment methods, and preventive measures of the VZV, with the aim of providing a theoretical basis for the development of new treatment and prevention methods for HZ. ABSTRACT Varicella zoster virus (VZV) is a ubiquitous human herpesvirus that establishes lifelong latency and causes ...
Lei Peng +8 more
wiley +1 more source

