Results 61 to 70 of about 156,575 (279)
Dynamics of Bacteriophage Genome Ejection In Vitro and In Vivo
, 2010 Bacteriophages, phages for short, are viruses of bacteria. The majority of phages contain a double-stranded DNA genome packaged in a capsid at a density of ~500 mg/ml. This high density requires substantial compression of the normal B form helix, leading
Molineux, Ian J., Panja, Debabrata
core +1 more source
Advanced Intelligent Discovery, EarlyView.This study integrates random matrix theory (RMT) and principal component analysis (PCA) to improve the identification of correlated regions in HIV protein sequences for vaccine design. PCA validation enhances the reliability of RMT‐derived correlations, particularly in small‐sample, high‐dimensional datasets, enabling more accurate detection of ...
Mariyam Siddiqah +3 more
wiley +1 more source
Viruses, 2016 The influenza glycoproteins, hemagglutinin (HA) and neuraminidase (NA), which are associated with the lipid raft, have the potential to initiate virion budding. However, the role of these viral proteins in infectious virion assembly is still unclear.
Naoki Takizawa +3 more
doaj +1 more source
Compartment-guided assembly of large-scale molecular models with Bentopy. [PDF]
Protein SciAbstract Molecular dynamics simulations of whole cells and organelles aim to transform cell biology by providing a molecular view into the crowded cellular environment. However, constructing suitable starting configurations remains a major bottleneck due to their size and complexity.
Westendorp MSS +6 more
europepmc +2 more sources
, 2019 This collection contains protocols for the extraction and preparation of DNA for long-read work and library amplification of long reads from microbial or viral DNA.
Marie Burris +2 more
openaire +1 more source
Endonucleases and simian virus 40 virions: origin of a virion-associated endonuclease [PDF]
Journal of Virology, 1976 The origin and role of the endonuclease activity associated with purified virions of simian virus 40, previously described by this and other laboratories, have been further investigated. We found that the enzymatic activity from virions of temperature-sensitive (ts) mutants is not more heat labile than that from wild-type virions.
D C, Dooley, M T, Ryzlak, H L, Ozer
openaire +2 more sources
Strain-dependent porcine circovirus type 2 (PCV2) entry and replication in T-lymphoblasts [PDF]
, 2019 Porcine circovirus type 2 (PCV2) is the etiological agent of PCV2-associated diseases (PCVAD). PCV2 targets lymphoblasts, and pigs suffering from PCVAD display lymphocyte depletion in lymphoid tissues. PCV2 infection of lymphoblasts has not been studied.
Nauwynck, Hans +2 more
core +1 more source
Identification Epitope on VP4 Protein of Senecavirus A Recognized by a Monoclonal Antibody
Animal Research and One Health, EarlyView.This study aims to identify conserved antigenic epitopes on the SVA VP4 protein using monoclonal antibodies, providing valuable tools for further exploring its functions and developing detection methods. SVA VP4 protein was expressed in Escherichia coli and purified with High‐Affinity Ni‐Charged Resin FF.
Liang Meng +7 more
wiley +1 more source
Role of Ezrin Phosphorylation in HIV-1 Replication
Frontiers in Microbiology, 2018 Host-cell expression of the ezrin protein is required for CXCR4 (X4)-tropic HIV-1 infection. Ezrin function is regulated by phosphorylation at threonine-567. This study investigates the role of ezrin phosphorylation in HIV-1 infection and virion release.
Haruka Kamiyama +11 more
doaj +1 more source
Poxvirus under the eyes of electron microscope
Applied Microscopy, 2022 Zoonotic poxvirus infections pose significant threat to human health as we have witnessed recent spread of monkeypox. Therefore, insights into molecular mechanism behind poxvirus replication cycle are needed for the development of efficient antiviral ...
Jaekyung Hyun
doaj +1 more source