Results 61 to 70 of about 1,645 (202)
Towards quantitative viromics for both double-stranded and single-stranded DNA viruses [PDF]
PeerJ, 2016 Background Viruses strongly influence microbial population dynamics and ecosystem functions. However, our ability to quantitatively evaluate those viral impacts is limited to the few cultivated viruses and double-stranded DNA (dsDNA) viral genomes ...
Simon Roux +8 more
doaj +2 more sources
Development of eNA Sampling for Early Detection of Pathogens in On‐Farm Water Sources
Environmental DNA, Volume 8, Issue 2, March/April 2026.We compare four water‐sampling methods for detecting microbial and viral eNA in livestock troughs and show all approaches effectively recover community profiles, supporting flexible, field‐ready surveillance of livestock pathogens. ABSTRACT Early detection of livestock pathogens is critical for mitigating risk and implementing timely control or ...
Maxine P. Piggott, Allyson Malpartida
wiley +1 more source
Identification of lead anti-human cytomegalovirus compounds targeting MAP4K4 via machine learning analysis of kinase inhibitor screening data [PDF]
, 2018 Chemogenomic approaches involving highly annotated compound sets and cell based high throughput screening are emerging as a means to identify novel drug targets.
Al-Ali, H +5 more
core +1 more source
Glycosylation and the global virome
Molecular Ecology, 2022 The sugars that coat the outsides of viruses and host cells are key to successful disease transmission, but they remain understudied compared to other molecular features. Understanding the comparative zoology of glycosylation - and harnessing it for predictive science - could help close the molecular gap in zoonotic risk assessment.
Cassandra L. Pegg +4 more
openaire +2 more sources
iMetaOmics, Volume 3, Issue 1, March 2026.Estuaries are vital hotspots for antibiotic resistance genes (ARGs) due to substantial antibiotic pollution. Although viruses have been proposed as key reservoirs and important disseminators of ARGs in environments, their contribution to the estuarine antibiotic resistome remains largely unknown.
Xiao‑Qing Luo +9 more
wiley +1 more source
Next-generation sequencing of dsRNA is greatly improved by treatment with the inexpensive denaturing reagent DMSO. [PDF]
, 2019 dsRNA is the genetic material of important viruses and a key component of RNA interference-based immunity in eukaryotes. Previous studies have noted difficulties in determining the sequence of dsRNA molecules that have affected studies of immune function
Delwart, Eric +2 more
core
Broad protection against influenza infection by vectored immunoprophylaxis in mice [PDF]
, 2013 Neutralizing antibodies that target epitopes conserved among many strains of influenza virus have been recently isolated from humans. Here we demonstrate that adeno-associated viruses (AAV) encoding two such broadly neutralizing antibodies are protective
Balazs, Alejandro B. +4 more
core +2 more sources
mSystems, 2018 Detection of viruses in the environment is heavily dependent on PCR-based approaches that require reference sequences for primer design. While this strategy can accurately detect known viruses, it will not find novel genotypes or emerging and invasive ...
Evelien M. Adriaenssens +5 more
doaj +1 more source
iMetaOmics, Volume 3, Issue 1, March 2026.Infectious bronchitis virus (IBV) represents a major threat to poultry production, with current control strategies offering limited protection. In this study, we demonstrate gut microbiome is a critical determinant of IBV resistance using fecal microbiota transplantation.
Ouyang Peng +22 more
wiley +1 more source
The Intra-Dependence of Viruses and the Holobiont. [PDF]
, 2017 Animals live in symbiosis with the microorganisms surrounding them. This symbiosis is necessary for animal health, as a symbiotic breakdown can lead to a disease state.
Grasis, Juris A
core