Results 71 to 80 of about 1,645 (202)
Signal transducer and activator of transcription 3 activation is associated with bladder cancer cell growth and survival [PDF]
, 2008 Background Constitutive activation of signal transducer and activator of transcription 3 (Stat3) signaling pathway plays an important role in several human cancers.
Hsieh Fu-Chuan +9 more
core +2 more sources
, 2023 By profiling 4,143 bat individuals from 40 species, we prepared a compendium of 8,176 viral metagenomes, named BtCN-Virome. It expands the known bat RNA virus diversity by at least 3.4 folds. The data set provides important insights into understanding the diversity and circulation pattern of bat viruses.
openaire +1 more source
VirusesBackground: Respiratory viruses significantly impact global morbidity and mortality, causing more disease in humans than any other infectious agent. Beyond pathogens, various viruses and bacteria colonize the respiratory tract without causing disease ...
Talya Conradie +6 more
doaj +1 more source
Viromics unveils extraordinary genetic diversity of the family Closteroviridae in wild citrus.
PLoS Pathogens, 2021 Our knowledge of citrus viruses is largely skewed toward virus pathology in cultivated orchards. Little is known about the virus diversity in wild citrus species.
Qiyan Liu +8 more
doaj +1 more source
Bluetongue in China: Current Status of Viruses, Vectors, Detection Methods, and Vaccines
Transboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.Bluetongue (BT) is a vector‐borne viral disease caused by the bluetongue virus (BTV), which can affect a variety of wild and domestic ruminants. Due to its significant impact on ruminant health and national economies, BT is classified as a notifiable multispecies disease by the World Organization for Animal Health (WOAH).
Jige Xin +9 more
wiley +1 more source
HCMV-encoded NK modulators: Lessons from in vitro and in vivo genetic variation [PDF]
, 2018 Human cytomegalovirus (HCMV) is under constant selective pressure from the immune system in vivo. Study of HCMV genes that have been lost in the absence of, or genetically altered by, such selection can focus research toward findings of in vivo ...
Fielding, Ceri A. +5 more
core +3 more sources
Probing the Viromic Frontiers [PDF]
mBio, 2015 ABSTRACT Modern molecular technology, and particularly high-throughput sequencing (HTS), has revolutionized virus discovery and expanded the depth and breadth of the virome. Recent HTS was used to identify and discover a previously undescribed member of the family Flaviviridae that has genomic features ...
openaire +3 more sources
KLF15 is a molecular link between endoplasmic reticulum stress and insulin resistance [PDF]
, 2013 Obesity places major demands on the protein folding capacity of the endoplasmic reticulum (ER), resulting in ER stress, a condition that promotes hepatic insulin resistance and steatosis. Here we identify the transcription factor, Kruppel-like factor 15 (
et al,, Urano, Fumihiko
core +9 more sources
Bacterial ribosomal RNA detection in cerebrospinal fluid using a viromics approach
Fluids and Barriers of the CNS, 2022 Key points We demonstrate that an unmodified viromic next-generation sequencing methodology effectively detects bacterial pathogen ribosomal RNA in cerebrospinal fluid samples. Sensitivity and specificity displayed pathogen dependent variation.
Cormac M. Kinsella +6 more
doaj +1 more source
Large-scale distribution of microbial and viral populations in the South Atlantic Ocean [PDF]
, 2016 Viruses are abundant, diverse and dynamic compo-nents of the marine environments and play a signi?-cant role in the ocean biogeochemical cycles. Toassess potential variations in the relation betweenviruses and microbes in different geographic regionsand ...
De Corte, D. +4 more
core +1 more source