Results 41 to 50 of about 6,591 (162)

A Thioredoxin Domain-Containing Protein Interacts with Pepino mosaic virus Triple Gene Block Protein 1 [PDF]

, 2018
Pepino mosaic virus (PepMV) is a mechanically-transmitted tomato pathogen of importance worldwide. Interactions between the PepMV coat protein and triple gene block protein (TGBp1) with the host heat shock cognate protein 70 and catalase 1 (CAT1 ...
Khechmar, Souheyla, Livieratos, Ioannis C., Mansour, Karima Ben, Mathioudakis, Matthaios M., Medina Piles, Vicente, Owen, Carolyn A., Sarris, Panagiotis F., Spanos, Theodore, Tomaszewska, Weronika   +8 more
core   +2 more sources

Live-Cell Imaging of Rhabdovirus-Induced Morphological Changes in Plant Nuclear Membranes

Molecular Plant-Microbe Interactions, 2005
Potato yellow dwarf virus (PYDV) and Sonchus yellow net virus (SYNV) belong to the genus Nucleorhabdovirus. These viruses replicate in nuclei of infected cells and mature virions accumulate in the perinuclear space after budding through the inner nuclear
Michael Goodin, Sharon Yelton, Debasish Ghosh, Stephanie Mathews, Judith Lesnaw   +4 more
doaj   +1 more source

Rotavirus viroplasm fusion and perinuclear localization are dynamic processes requiring stabilized microtubules. [PDF]

PLoS ONE, 2012
Rotavirus viroplasms are cytosolic, electron-dense inclusions corresponding to the viral machinery of replication responsible for viral template transcription, dsRNA genome segments replication and assembly of new viral cores. We have previously observed
Catherine Eichwald, Francesca Arnoldi, Andrea S Laimbacher, Elisabeth M Schraner, Cornel Fraefel, Peter Wild, Oscar R Burrone, Mathias Ackermann   +7 more
doaj   +1 more source

Principles of RNA recruitment to viral ribonucleoprotein condensates in a segmented dsRNA virus

eLife, 2023
Rotaviruses transcribe 11 distinct RNAs that must be co-packaged prior to their replication to make an infectious virion. During infection, nontranslating rotavirus transcripts accumulate in cytoplasmic protein-RNA granules known as viroplasms that ...
Sebastian Strauss, Julia Acker, Guido Papa, Daniel Desirò, Florian Schueder, Alexander Borodavka, Ralf Jungmann   +6 more
doaj   +1 more source

Physicochemical analysis of rotavirus segment 11 supports a 'modified panhandle' structure and not the predicted alternative tRNA-like structure (TRLS) [PDF]

, 2013
.Rotaviruses are a major cause of acute gastroenteritis, which is often fatal in infants. The viral genome consists of 11 double-stranded RNA segments, but little is known about their cis-acting sequences and structural elements.
A Heerschap, A L’Hernault, A Wilm, AE Simon, Andrew M. Lever, AR Gruber, BI Klasens, D Chen, D Chen, D Yue, D Yue, E Madore, E Matsuo, EC Hutchinson, Emily Manktelow, EV Puglisi, H Heus, HD Cho, J Jia, JC Kenyon, Jonathan Lever, JR Gog, JT Patton, Laura E. Easton, LE Easton, M Barro, M Estes, MA Tortorici, MW Friederich, N Figueroa, P Annamalai, Peter J. Lukavsky, PJ Lukavsky, R Giegé, R Giegé, RC Olsthoorn, S Nishimura, SC Chen, SH Bernhart, Subhajit Biswas, T Nagaike, TW Dreher, TW Dreher, TW Dreher, TW Dreher, Ulrich Desselberger, W Li, Wilson Li   +47 more
core   +1 more source

Mapping of transcription termination within the S segment of SFTS phlebovirus facilitated the generation of NSs-deletant viruses [PDF]

, 2017
SFTS phlebovirus (severe fever with thrombocytopenia syndrome virus; SFTSV) is an emerging tick-borne bunyavirus that was first reported in China in 2009. Here we report the generation of a recombinant SFTSV (rHB29NSsKO) that cannot express the viral non-
Brennan, Benjamin, Elliott, Richard M., Rezelj, Veronica V.   +2 more
core   +1 more source

Tomato fruit blotch virus cytopathology strengthens evolutionary links between plant blunerviruses and insect negeviruses

Scientia Agricola, 2022
Tomato fruit blotch virus (ToFBV) is a blunervirus that causes blotches on mature tomato (Solanum lycopersicon L.) fruits in Italy and Australia in 2020, and was newly detected in Brazil. A cytological study on pericarp tissues from the blotched areas of
Elliot Watanabe Kitajima, Erich Yukio Tempel Nakasu, Alice Kazuko Inoue-Nagata, Renato Barbosa Salaroli, Pedro Luis Ramos-González   +4 more
doaj   +1 more source

Analysis of genetic diversity and molecular evolution of human group B rotaviruses based on whole genome segments [PDF]

, 2010
Group B rotavirus (GBR) is a rare enteric pathogen that causes severe diarrhoea, primarily in adults. Nearly full-length sequences of all 11 RNA segments were determined for human GBRs detected recently in India (IDH-084 in 2007, IC-008 in 2008 ...
Ahmed, Aung, B. Ganesh, Barman, Brown, Cook, D. Yamamoto, Dai, Dammann, Deo, Dormitzer, Fang, Ghosh, Ghosh, Gouvea, Hung, Ishino, Ito, Kobayashi, Kuga, M. Chawla-Sarkar, M. M. Alam, N. Kobayashi, Nagashima, Nakata, Paul, Polderman, Rahman, S. Ghosh, Sanekata, Shen, T. Krishnan, T. S. Aung, Tsunemitsu, Vende, Wang, Wang, Yang   +37 more
core   +1 more source

Second-generation nitazoxanide derivatives: thiazolides are effective inhibitors of the influenza A virus [PDF]

, 2018
Aim: The only small molecule drugs currently available for treatment of influenza A virus (IAV) are M2 ion channel blockers and sialidase inhibitors. The prototype thiazolide, nitazoxanide, has successfully completed Phase III clinical trials against ...
Andrew V Stachulski, Brian M Eklov, Chandrakala Pidathala, Eleanor C Row, Giuseppe Belardo, J Edward Semple, Jean-Francois Rossignol, La Frazia S, M Gabriella Santoro, Mazhar Iqbal, Neil G Berry, Paul M O'Neill, Podlogar BL, Rossignol JF, Rossignol JF, Sara Piacentini, Sarah A Allman, Simone La Frazia   +17 more
core   +1 more source

Phase Transitions Drive the Formation of Vesicular Stomatitis Virus Replication Compartments

mBio, 2018
RNA viruses that replicate in the cell cytoplasm typically concentrate their replication machinery within specialized compartments. This concentration favors enzymatic reactions and shields viral RNA from detection by cytosolic pattern recognition ...
Bianca S. Heinrich, Zoltan Maliga, David A. Stein, Anthony A. Hyman, Sean P. J. Whelan   +4 more
doaj   +1 more source