Involvement of PRRSV NSP3 and NSP5 in the autophagy process
Virology Journal, 2019 Background Autophagy is an essential process in eukaryotic cells in which autophagosomes form to deliver cellular organelles and long-lived proteins to lysosomes for degradation. Many studies have recently identified the regulatory mechanisms involved in
Wei Zhang +4 more
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Association of rotavirus viroplasms with microtubules through NSP2 and NSP5 [PDF]
Memorias do Instituto Oswaldo Cruz, 2006 Rotavirus replication and virus assembly take place in electrodense spherical structures known as viroplasms whose main components are the viral proteins NSP2 and NSP5.
Claudio Cabral-Romero +1 more
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Viruses, 2019 Feline infectious peritonitis (FIP), caused by virulent feline coronavirus, is the leading infectious cause of death in cats. The type I interferon (type I IFN)-mediated immune responses provide host protection from infectious diseases.
Si Chen +8 more
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Studies On Phosphorylation And Oligomerization Of Rotavirus Nonstructural Protein 5 (NSP5) And Cellular Pathways That Regulate Virus Replication [PDF]
, 2012 Rotavirus is one of the leading etiological agents of gastroenteritis in young of many species including humans worldwide and is responsible for about 600,000 infant deaths per annum. Rotavirus belongs to the Reoviridae family, and its genome is composed
Namsa, Nima Dondu
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Rotavirus Genomic RNA Complex Forms via Specific RNA-RNA Interactions: Disruption of RNA Complex Inhibits Virus Infectivity. [PDF]
, 2017 Rotavirus (RV), a member of the Reoviridae family, causes infection in children and infants, with high morbidity and mortality. To be viable, the virus particle must package a set of eleven RNA segments.
Celma, Cristina C +3 more
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Physicochemical analysis of rotavirus segment 11 supports a 'modified panhandle' structure and not the predicted alternative tRNA-like structure (TRLS) [PDF]
, 2013 .Rotaviruses are a major cause of acute gastroenteritis, which is often fatal in infants. The viral genome consists of 11 double-stranded RNA segments, but little is known about their cis-acting sequences and structural elements.
A Heerschap +47 more
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Equine-like G3 rotavirus in Hungary, 2015 – Is it a novel intergenogroup reassortant pandemic strain? [PDF]
, 2016 Novel, intergenogroup reassortant G3 rotavirus strains are spreading in at least three continents: Asia, Australia, and Europe. The present study provides evidence that a closely related G3P[8] strain circulated in Hungary during 2015.
Agócs, Zsófia +6 more
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Review of software applications for deriving collocations [PDF]
, 2006 The field of collocation extraction has enjoyed considerable growth and vitality from the 1990s onwards. Our research uncovered a multitude of software programs that can derive collocations from textual data, but also introduced the following question ...
Anagnostou, N.K., Weir, G.R.S.
core
Rotavirus NSP4: Cell type-dependent transport kinetics to the exofacial plasma membrane and release from intact infected cells [PDF]
, 2011 Background Rotavirus NSP4 localizes to multiple intracellular sites and is multifunctional, contributing to RV morphogenesis, replication and pathogenesis.
Thomas F Gibbons +8 more
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SARS-CoV-2 main protease suppresses type I interferon production by preventing nuclear translocation of phosphorylated IRF3 [PDF]
, 2021 Suppression of type I interferon (IFN) response is one pathological outcome of the infection of highly pathogenic human coronaviruses. To effect this, severe acute respiratory syndrome coronavirus (SARS-CoV) and SARS-CoV-2 encode multiple IFN antagonists.
Fung, SY +4 more
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