Results 41 to 50 of about 7,665 (202)
Communications Biology, 2023 A critical step for SARS-CoV-2 assembly and maturation involves the autoactivation of the main protease (MProWT) from precursor polyproteins. Upon expression, a model precursor of MProWT mediates its own release at its termini rapidly to yield a mature ...
Annie Aniana +6 more
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Viruses, 2022 The dysregulation of host signaling pathways plays a critical role in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and viral pathogenesis. While a number of viral proteins that can block type I IFN signaling have been identified,
Abhishek Kumar +3 more
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Computational and Structural Biotechnology Journal, 2021 There is an urgent need to develop effective treatments for coronavirus disease 2019 (COVID-19), which is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).
Fangfang Yan, Feng Gao
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Phosphorylation Generates Different Forms of Rotavirus NSP5
Journal of General Virology, 1996 NSP5 (non-structural protein 5) is one of two proteins encoded by genome segment 11 of group A rotaviruses. In virus-infected cells NSP5 accumulates in the virosomes and is found as two polypeptides with molecular masses of 26 and 28 kDa (26K and 28K proteins).
I, Afrikanova +3 more
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Majalah Obat Tradisional, 2022 Green tea catechin compounds (Camellia sinensis L. Kuntze) have an antiviral activity such as influenza, hepatitis B, hepatitis C, herpes simplex virus, HIV, and proven in vitro antiviral influenza against NSP5 in SARS CoV.
Roihatul Mutiah +3 more
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Influence of nut shell powder content on the tribological properties of recycled polyolefin composites [PDF]
, 2016 The purpose of this study is to investigate the influence of nut shell powder (NSP) content on the tribological properties of recycled polyolefin (R-PO) composites. NSP was previously grinded the dried nut shell by crusher machine cryogenically in liquid
Hoshikawa, Akinori +5 more
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Rotavirus NSP5 orchestrates recruitment of viroplasmic proteins
Journal of General Virology, 2010 Rotavirus genome replication and the first steps of virus morphogenesis take place in cytoplasmic viral factories, called viroplasms, containing four structural (VP1, VP2, VP3 and VP6) and two non-structural (NSP2 and NSP5) proteins. NSP2 and NSP5 have been shown to be essential for viroplasm formation and, when co-expressed in uninfected cells, to ...
R. Contin +3 more
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In vitro and in vivo characterization of SARS-CoV-2 strains resistant to nirmatrelvir
Nature Communications, 2023 Nirmatrelvir, an oral antiviral agent that targets a SARS-CoV-2 main protease (3CLpro), is clinically useful against infection with SARS-CoV-2 including its omicron variants.
Maki Kiso +5 more
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Rotavirus genetic diversity, disease association, and temporal change in hospitalized rural Kenyan children [PDF]
, 1988 Background. The effectiveness of rotavirus vaccines will be dependent on the immunity conferred against prevalent and emergent variants causing severe diarrheal disease.
Nokes, D. James +8 more
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Novel G9 rotavirus strains co-circulate in children and pigs, Taiwan [PDF]
, 2017 Molecular epidemiologic studies collecting information of the spatiotemporal distribution of rotavirus VP7 (G) and VP4 (P) genotypes have shown evidence for the increasing global importance of genotype G9 rotaviruses in humans and pigs.
Bányai, Krisztián +8 more
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