Rotavirus NSP4: Cell type-dependent transport kinetics to the exofacial plasma membrane and release from intact infected cells [PDF]
Background Rotavirus NSP4 localizes to multiple intracellular sites and is multifunctional, contributing to RV morphogenesis, replication and pathogenesis.
Thomas F Gibbons +8 more
core +4 more sources
Assembly of Viroplasm and Virus-like Particles of Rotavirus by a Semliki Forest Virus Replicon
In this study we have used an expression system based on Semliki Forest virus (SFV) to study assembly and intracellular localization of certain capsid proteins of rotavirus in neurons and mammalian epithelial cells. The complete genes of vp2 (vp2A) and vp6 (vp6A) of group A rotavirus (SA-11) and gene 5 encoding vp6 (vp6C) of porcine group C rotavirus ...
Nilsson, M. +4 more
openaire +3 more sources
Two non-structural rotavirus proteins, NSP2 and NSP5, form viroplasm-like structures in vivo.
In rotavirus-infected cells, the non-structural proteins NSP5 and NSP2 localize in complexes called viroplasms, where replication and assembly occur. Recently, we have demonstrated direct interaction of NSP5 with NSP2, and as a consequence of that, up-regulation of NSP5 hyperphosphorylation.
E, Fabbretti +3 more
openaire +2 more sources
Virus replication can cause extensive rearrangement of host cell cytoskeletal and membrane compartments leading to the "cytopathic effect" that has been the hallmark of virus infection in tissue culture for many years. Recent studies are beginning to redefine these signs of viral infection in terms of specific effects of viruses on cellular processes ...
Netherton, Christopher +3 more
openaire +3 more sources
Flexibility of the Rotavirus NSP2 C-Terminal Region Supports Factory Formation via Liquid-Liquid Phase Separation. [PDF]
Nichols SL +6 more
europepmc +1 more source
Rotavirus Viroplasm Biogenesis Involves Microtubule-Based Dynein Transport Mediated by an Interaction between NSP2 and Dynein Intermediate Chain. [PDF]
Jing Z +13 more
europepmc +1 more source
Rotavirus capping enzyme VP3 inhibits interferon expression by inducing MAVS degradation during viral replication. [PDF]
Dai J +3 more
europepmc +1 more source
A second cauliflower mosaic virus gene product influences the structure of the viral inclusion body [PDF]
Givord, Louise +6 more
core
Comparative electron microscopic observation of viroplasms induced by plant viruses.
S. YAMASHITA, Y. DOI, E. W. KITAJIMA
openaire +2 more sources

