Results 171 to 180 of about 4,749 (194)

Functional redundancy in Oxa1-family insertases supports robust membrane insertion of influenza A virus M2 viroporin

Diwo C, Alenquer M, Zhou S, Digard P, Adrain C, Amorim MJ.   +5 more
europepmc   +1 more source

Membrane association prevents premature degradation and mitigates inefficient biogenesis of suboptimal membrane proteins

Diwo C, Alenquer M, Adrain C, Amorim MJ.
europepmc   +1 more source

Death by viroporin

Nature Reviews Microbiology, 2007
exaly   +3 more sources

Re-evaluating the p7 viroporin structure

Nature, 2018
Juan H Bolivar, Mario Hensen, Jolyon K Claridge   +2 more
exaly   +4 more sources

Membrane Integration of Poliovirus 2B Viroporin [PDF]

Journal of Virology, 2011
ABSTRACT Virus infections can result in a variety of cellular injuries, and these often involve the permeabilization of host membranes by viral proteins of the viroporin family. Prototypical viroporin 2B is responsible for the alterations in host cell membrane permeability that take place in enterovirus-infected cells. 2B protein
Luis Martinez-Gil, Manuel Bañó-Polo, Natalia Redondo   +2 more
exaly   +6 more sources

Viroporin activity of murine hepatitis virus E protein [PDF]

FEBS Letters, 2005
The viroporin activity of the E protein from murine hepatitis virus (MHV), a member of the coronaviruses, was analyzed. Viroporins are a growing family of viral proteins able to enhance membrane permeability, promoting virus budding. Initially, the MHV E gene was inducibly expressed in Escherichia coli cells, leading to the arrest of bacterial growth ...
Meritxell Garcia-Quintanilla, Miguel A. Sanz, Luis Carrasco   +2 more
exaly   +3 more sources

NS2A comprises a putative viroporin of Dengue virus 2 [PDF]

Virulence, 2017
During infection with Dengue virus (DENV), host cells undergo a series of detrimental functional changes, including profound remodelling and redistribution of cell membrane structures,1,4 which giv...
Gaurav Shrivastava, Moisés León-Juárez, Goldie Oza   +2 more
exaly   +3 more sources

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[The antiviral targeting potential of viroporins].

Ugeskrift for laeger, 2022
Viroporins are ion channels found in many viruses, where they contribute to virus life cycle and thereby pathogenesis. Viroporin targeting is a known, yet largely unexplored, therapeutic strategy so far only used in Influenza A with the drugs amantadine and rimantadine.
John D, Sund, Signe, Bollerup, Jekob B, Glamann, Caroline An, Vinten, Louise R, Jensen, Trine L, Toft-Bethelsen, Bo H, Bentzen, Thomas N, Kledal, Nina, Weis, Mette, Rosenkilde   +9 more
openaire   +1 more source