Results 11 to 20 of about 17,431 (301)
Delivery and Biosafety of Oncolytic Virotherapy [PDF]
Frontiers in Oncology, 2020 In recent years, oncolytic virotherapy has emerged as a promising anticancer therapy. Oncolytic viruses destroy cancer cells, without damaging normal tissues, through virus self-replication and antitumor immunity responses, showing great potential for ...
Lizhi Li +10 more
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Advances in oncolytic virotherapy
Communications Medicine, 2022 Recent years have seen rapid advances in the preclinical development and clinical evaluation of oncolytic (cancer-lysing) virus-based therapies, and these are emerging as treatment modality for some cancers.
Stephen J. Russell +3 more
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Oncolytic virotherapy as immunotherapy
Science, 2021 Recognizing immune responses to oncolytic virotherapy opens the way for new ...
Alan, Melcher +2 more
openaire +3 more sources
Annals of Hepatology, 2008 Current oncolytic virotherapy strategies are based in the accumulated understanding of the common molecular mechanisms displayed during cell transformation and viral infection, like cell cycle and apoptosis deregulations.
Daniel Cervantes-García; +3 more
doaj +4 more sources
Pharmaceutics, 2022 Oncolytic virotherapy is a type of nanomedicine with a dual antitumor mechanism. Viruses are engineered to selectively infect and lyse cancer cells directly, leading to the release of soluble antigens which induce systemic antitumor immunity ...
Qing Ji +4 more
doaj +2 more sources
Oncolytic virotherapy: basic principles, recent advances and future directions
Signal Transduction and Targeted Therapy, 2023 Oncolytic viruses (OVs) have attracted growing awareness in the twenty-first century, as they are generally considered to have direct oncolysis and cancer immune effects.
Danni Lin, Yinan Shen, T. Liang
semanticscholar +1 more source
Oncolytic DNX-2401 virotherapy plus pembrolizumab in recurrent glioblastoma: a phase 1/2 trial
Nature Network Boston, 2023 Immune-mediated anti-tumoral responses, elicited by oncolytic viruses and augmented with checkpoint inhibition, may be an effective treatment approach for glioblastoma. Here in this multicenter phase 1/2 study we evaluated the combination of intratumoral
F. Nassiri +38 more
semanticscholar +1 more source
Nature Biotechnology, 2012 Oncolytic virotherapy is an emerging treatment modality that uses replication-competent viruses to destroy cancers. Recent advances include preclinical proof of feasibility for a single-shot virotherapy cure, identification of drugs that accelerate intratumoral virus propagation, strategies to maximize the immunotherapeutic action of oncolytic viruses ...
Russell, Stephen J +2 more
openaire +2 more sources
Nature Communications, 2023 Oncolytic adenoviruses (Ads)-mediated anti-tumor activity is related to virus-promoted autophagy in tumor cells. Here the authors describe the design of a microbial nanocomposite based on Ads-encapsulated in bacterial outer membrane vesicles to promote ...
Weiyue Ban +10 more
semanticscholar +1 more source
Frontiers in Cellular and Infection Microbiology, 2023 Recent reports have revealed that oncolytic viruses (OVs) play a significant role in cancer therapy. The infection of OVs such as oncolytic vaccinia virus (OVV), vesicular stomatitis virus (VSV), parvovirus, mammalian reovirus (MRV), human adenovirus ...
Yi-Ying Wu +4 more
semanticscholar +1 more source