Results 11 to 20 of about 18,764 (290)
Annals of Hepatology, 2008 Current oncolytic virotherapy strategies are based in the accumulated understanding of the common molecular mechanisms displayed during cell transformation and viral infection, like cell cycle and apoptosis deregulations.
Daniel Cervantes-García; +3 more
doaj +4 more sources
Oncolytic Virotherapy in Glioma Tumors [PDF]
International Journal of Molecular Sciences, 2020 Glioma tumors are one of the most devastating cancer types. Glioblastoma is the most advanced stage with the worst prognosis. Current therapies are still unable to provide an effective cure. Recent advances in oncolytic immunotherapy have generated great expectations in the cancer therapy field. The use of oncolytic viruses (OVs) in cancer treatment is
Sergio Rius‐Rocabert +4 more
openalex +5 more sources
Syncytia Formation in Oncolytic Virotherapy [PDF]
Molecular Therapy - Oncolytics, 2019 Oncolytic virotherapy uses replication-competent virus as a means of treating cancer. Whereas this field has shown great promise as a viable treatment method, the limited spread of these viruses throughout the tumor microenvironment remains a major challenge. To overcome this issue, researchers have begun looking at syncytia formation as a novel method
Chase Burton, Eric Bartee
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Advances in oncolytic virotherapy
Communications Medicine, 2022 Recent years have seen rapid advances in the preclinical development and clinical evaluation of oncolytic (cancer-lysing) virus-based therapies, and these are emerging as treatment modality for some cancers.
Stephen J. Russell +3 more
doaj +3 more sources
Oncolytic virotherapy as immunotherapy
Science, 2021 Description Recognizing immune responses to oncolytic virotherapy opens the way for new combinations Oncolytic virus (OV) therapy is now something of a misnomer.
A. Melcher, K. Harrington, R. Vile
semanticscholar +3 more sources
Virotherapy in Head and Neck Cancer
Oral Oncology ReportsHead and neck cancer, comprising a diverse group of malignancies, presents significant challenges in terms of treatment efficacy and patient outcomes.
Zhan Wang
doaj +2 more sources
Nature Biomedical Engineering, 2021 Non-invasive imaging methods for detecting intratumoural viral spread and host responses to oncolytic virotherapy are either slow, lack specificity or require the use of radioactive or metal-based contrast agents.
O. Perlman +9 more
semanticscholar +3 more sources
Oncolytic viruses: Revolutionising the fight against tumours. [PDF]
Clin Transl MedClinical and Translational Medicine, Volume 15, Issue 10, October 2025.
Zhao Z, Shen Y, Liang T.
europepmc +2 more sources
Nature Biotechnology, 2012 Oncolytic virotherapy is an emerging treatment modality that uses replication-competent viruses to destroy cancers. Recent advances include preclinical proof of feasibility for a single-shot virotherapy cure, identification of drugs that accelerate intratumoral virus propagation, strategies to maximize the immunotherapeutic action of oncolytic viruses ...
Russell, Stephen J +2 more
openaire +3 more sources
Vaccines, 2022 The Omicron SARS-CoV-2 variant has been designated as a variant of concern because its spike protein is heavily mutated. In particular, the Omicron spike is mutated at five positions (K417, N440, E484, Q493, and N501) that have been associated with ...
Karen V. Kibler +9 more
doaj +1 more source