Results 31 to 40 of about 17,431 (301)
Frontiers in Cardiovascular Medicine, 2021 Diffuse alveolar hemorrhage (DAH) is one of the most serious clinical complications of systemic lupus erythematosus (SLE). The prevalence of DAH is reported to range from 1 to 5%, but while DAH is considered a rare complication there is a reported 50–80%
Qiuyun Guo +13 more
doaj +1 more source
Oncolytic herpes viruses, chemotherapeutics, and other cancer drugs [PDF]
, 2013 Oncolytic viruses are emerging as a potential new way of treating cancers. They are selectively replication-competent viruses that propagate only in actively dividing tumor cells but not in normal cells and, as a result, destroy the tumor cells by ...
Braidwood, L. +3 more
core +1 more source
Advances in Materials, 2022 A unique robotic medical platform is designed by utilizing cell robots as the active “Trojan horse” of oncolytic adenovirus (OA), capable of tumor‐selective binding and killing.
Z. Cong +11 more
semanticscholar +1 more source
Oncolytic Virus Infection Modulates Lysine Acetyltransferase in Gliomas: Comprehensive Analysis and Experimental Validation of KAT8 in Glioma. [PDF]
J Cell Mol MedABSTRACT Oncolytic virotherapy, which uses engineered viruses to selectively target tumour cells, has emerged as a potential treatment in glioma. However, how oncolytic virus infection modulates lactylation enzymes in gliomas remains unclear. The RNA‐seq data after oncolytic virus EV‐A71 infection on glioma cells was analysed to screen and lysine ...
Yin X +6 more
europepmc +2 more sources
Tumor-Associated Macrophages/Microglia in Glioblastoma Oncolytic Virotherapy: A Double-Edged Sword
International Journal of Molecular Sciences, 2022 Oncolytic virotherapy is a rapidly progressing field that uses oncolytic viruses (OVs) to selectively infect malignant cells and cause an antitumor response through direct oncolysis and stimulation of the immune system.
Sarah E. Blitz +10 more
semanticscholar +1 more source
Advances in the design and development of oncolytic measles viruses. [PDF]
, 2015 A successful oncolytic virus is one that selectively propagates and destroys cancerous tissue without causing excessive damage to the normal surrounding tissue. Oncolytic measles virus (MV) is one such virus that exhibits this characteristic and thus has
Hutzen, Brian +2 more
core +1 more source
Personalized virotherapy in cancer
Aging, 2015 After decades of intensive research, pancreatic adenocarcinoma (PDAC) remains a highly lethal disease with a median survival time that does not exceed 6.5 months [1]. Since more than 80% of patients present with advanced metastatic disease, systemic chemotherapy remains the only treatment.
Cafferata Eduardo G +1 more
openaire +4 more sources
Oncolytic Virotherapy with Myxoma Virus [PDF]
Journal of Clinical Medicine, 2020 Oncolytic viruses are one of the most promising novel therapeutics for malignant cancers. They selectively infect and kill cancer cells while sparing the normal counterparts, expose cancer- specific antigens and activate the host immune system against both viral and tumor determinants.
Masmudur M. Rahman, Grant McFadden
openaire +3 more sources
The use of oncolytic virotherapy in the neoadjuvant setting
Journal for ImmunoTherapy of Cancer, 2022 Surgical removal of tumors remains a front-line therapy for many types of cancer. However, this treatment often fails to eradicate disease due to either recurrence of the original tumor or development of distant micrometastases.
Raquela J. Thomas, E. Bartee
semanticscholar +1 more source
Frontiers in Immunology, 2021 Immune checkpoint inhibitors such as anti-PD-1 have revolutionized the field of oncology over the past decade. Nevertheless, the majority of patients do not benefit from them.
Victor Cervera-Carrascon +21 more
doaj +1 more source