Results 71 to 80 of about 11,979 (257)
Oncolytic virotherapy and the current approaches in veterinary medicine
German Journal of Veterinary Research, 2022 Cancer has an increasing incidence worldwide in humans and animals. In addition to traditional treatments such as surgery, radiotherapy, and chemotherapy, there is a search for new treatment strategies for cancer treatment.
Bengu Bilgic, Banu Dokuzeylul, Mehmet Or
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Advanced Science, EarlyView.A personalized nanovaccine combining PLGA‐encapsulated heat‐inactivated CVB3 and membranes from CVB3‐infected breast cancer cells stimulates potent antitumor immunity. It reduces immunosuppressive markers, enhances immune activation, and improves survival in vivo.
Amirhossein Bahreyni +6 more
wiley +1 more source
Journal of Biomedical SciencesBackground As of 2020, hepatocellular carcinoma (HCC), a form of liver cancer, stood as the third most prominent contributor to global cancer-related mortality. Combining immune checkpoint inhibitors (ICI) with other therapies has shown promising results
D. Ou +5 more
semanticscholar +1 more source
Oncolytic virotherapy for pancreatic cancer [PDF]
Expert Reviews in Molecular Medicine, 2011 Within the past decade, many oncolytic viruses (OVs) have been studied as potential treatments for pancreatic cancer and some of these are currently under clinical trials. The applicability of certain OVs, such as adenoviruses, herpesviruses and reoviruses, for the treatment of pancreatic cancer has been intensively studied for several years, whereas ...
Grant McFadden +2 more
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A progressive stage IIIB melanoma treated with oncolytic ECHO-7 virus: A case report
SAGE Open Medical Case Reports, 2020 Melanoma is an aggressive skin cancer form with a grave prognosis. Current results suggest that oncolytic virus treatment of melanoma has a high therapeutic potential. ECHO-7 (Rigvir) is the first oncolytic virus registered in Latvia.
Vladimirs Sorokins +6 more
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Nature Biomedical Engineering, 2021 Non-invasive imaging methods for detecting intratumoural viral spread and host responses to oncolytic virotherapy are either slow, lack specificity or require the use of radioactive or metal-based contrast agents.
O. Perlman +9 more
semanticscholar +1 more source
Virotherapy – cancer targeted pharmacology
Drug Discovery Today, 2012 Building on their success in vaccination, many groups are now exploring the use of viruses as anticancer agents. In general, viral therapeutics provide the possibility to express anticancer proteins directly at the tumour site, decreasing exposure to normal tissue during delivery and maximising therapeutic index.
Tedcastle, A +4 more
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Micro‐ and nanomotors in biomedical applications
Responsive Materials, EarlyView.Micro‐ and nanomotors (MNMs), as autonomous devices converting chemical or external energy into mechanical propulsion, have emerged as transformative drug delivery platforms in biomedicine. This review systematically outlines the design principles governing MNMs' propulsion and operation, highlights the applications of MNMs in disease treatment, and ...
Xiangyu Meng, Yuqi Tang, Quan Li
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The Multifaceted Role of Macrophages in Oncolytic Virotherapy
Viruses, 2021 One of the cancer hallmarks is immune evasion mediated by the tumour microenvironment (TME). Oncolytic virotherapy is a form of immunotherapy based on the application of oncolytic viruses (OVs) that selectively replicate in and induce the death of tumour
Laura Hofman +2 more
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Plant Biotechnology Journal, EarlyView.ABSTRACT The plant virus cowpea mosaic virus (CPMV) is being developed as a drug candidate for intratumoral immunotherapy for solid tumours. Data from preclinical studies in mice and rats as well as clinical studies in canine cancer patients demonstrate potent efficacy and an excellent safety profile.
Patrick Opdensteinen +3 more
wiley +1 more source