Results 71 to 80 of about 3,771,266 (288)

Combating Inflammation and Promoting Anabolism in Osteoarthritic Cartilage Defect With an MMP13‐Sensing Dual‐Drug Scaffold

Advanced Science, EarlyView.
ABSTRACT Osteoarthritis (OA) is a widespread degenerative joint condition marked by progressive cartilage breakdown, and a chronic inflammatory microenvironment, where conventional therapies largely fail to halt disease progression. To address this unmet need, an intra‐articularly implantable, disease‐responsive scaffold was developed for combinatorial
Zhen Zhang, Bangheng Liu, Yulei Mu, Huiqun Zhou, Liang Ma, Chenjie Xu, Dong‐An Wang   +6 more
wiley   +1 more source

Virtual Character Animations from Human Body Motion by Automatic Direct and Inverse Kinematics-based Mapping

EAI Endorsed Transactions on Creative Technologies, 2015
Motion capture systems provide an efficient and interactive solution for extracting information related to a human skeleton, which is often exploited to animate virtual characters.
Andrea Sanna, Fabrizio Lamberti, Gianluca Paravati, Gilles Carlevaris, Paolo Montuschi   +4 more
doaj   +1 more source

Cerium Nanoparticle‐Mediated Inhibition of the NSUN2/m5C Axis Suppresses Synovial Aggression in Rheumatoid Arthritis

Advanced Science, EarlyView.
A novel epitranscriptomic mechanism in rheumatoid arthritis is uncovered: NSUN2 promotes disease via m5C‐dependent stabilization of ICMT mRNA, fueling the migration and invasion of pathogenic RA FLS. Targeting this axis with engineered nanoparticles (Ce/SAA NPs) effectively inhibits disease progression, presenting a precise therapeutic strategy ...
Ruiru Li, Simin Chen, Huijuan Hu, Shiyao Wu, Jingnan Wang, Kai Sun, Chenxi Peng, Suling Liu, Shuoyang Zhang, Yu Kuang, Wei Chen, Qian Qiu, Liuqin Liang, Yu Wen, Hanshi Xu, Youjun Xiao   +15 more
wiley   +1 more source

Guia de bones pràctiques

, 2020
Fitxa divulgativa del Banc d'Experiències i Bones ...
Banc d'Experiències i Bones Pràctiques, Gerència d'Àrea de Drets Socials, Salut, Cooperació i Comunitat   +1 more
core   +2 more sources

Ontogenetic similarities between giraffe and sauropod neck osteological mobility.

PLoS ONE, 2020
The functional morphology of sauropod dinosaur long necks has been studied extensively, with virtual approaches yielding results that are difficult to obtain with actual fossils, due to their extreme fragility and size.
Daniel Vidal, Pedro Mocho, Adrián Páramo, José Luis Sanz, Francisco Ortega   +4 more
doaj   +1 more source

Enhancing Super‐Resolution Spatial Transcriptomics Data by Transfer Learning

Advanced Science, EarlyView.
SpotZoomer employs a transfer‐learning‐based strategy to enhance the resolution of Visium data by leveraging available high‐resolution priors. The resulting super‐resolved maps enable sharper delineation of cell boundaries and more precise inference of cell–cell communication patterns that would otherwise remain obscured at native resolution.
Xiaoyu Li, Lihua Zhang, Wenwen Min
wiley   +1 more source

A Global Methane Observation System to Reduce Uncertainty for Anthropogenic and Natural Sources and Sinks for Detecting and Attributing Climate Feedbacks

Advanced Science, EarlyView.
Conceptual illustration of a Global Ecosystem Methane Observing System (GEM‐OS) integrating satellites, aircraft, atmospheric networks, and ecosystem measurements to quantify methane emissions from anthropogenic and natural sources. The multi‐scale observing framework improves source attribution, reduces uncertainty in regional methane budgets, and ...
P. Ciais, S. Peng, J. Chang, F. Li, Q. Zhu, K. Yuan, G. Hugelius, H. Li, Y. Cai, F. Chevallier, K. Tibrewal, E. A. Kort, K. Arndt, J. Watts, B. Buma, N. Besic, P. I. Palmer, H. Cadillo‐Quiroz, E. Euskirchen, M. J. Gondwe, A. Hoyt, R. Jackson, S. Malone, D. Monteverde, S. Natali, M. Ramonet, C. Rey‐Sanchez, L. B. Sagang, E. A. G. Schuur, R. Vargas, R. Varner, Z. Zhang, B. Poulter   +32 more
wiley   +1 more source

Three-Dimensional Planning and Surgical Correction of Bilateral Developmental Valgus Deformity of the Manus in a Dog

Animals
A one-year-old, 48 kg, male neutered, Great Dane presented for bilateral thoracic limb lameness ascribed to an apparent developmental valgus deformity of both manus.
Francesca P. Solari, Mu Young Kim, Federico R. Vilaplana Grosso, Adam H. Biedrzycki, Daniel D. Lewis   +4 more
doaj   +1 more source

Machine Learning‐Driven Design of Multicomponent Bone Inorganic Matrix Mimicking Scaffolds for Osteogenesis Enhanced by Neurogenesis

Advanced Science, EarlyView.
Schematic illustration of development of experimental datasets and algorithm models, screening and preparation of the scaffolds and their applications in vivo. ABSTRACT Bone defects require materials with osteogenic, neurogenic, and angiogenic activity, yet designing such materials within high‐dimensional compositional spaces remains challenging. Here,
Kunlu Lin, Ying Yang, Chuyao Zhou, Hanyue Mao, Zhiquan Zhang, Libangxi Liu, Xiaoying Yu, Haoming Liu, Long Liu, Xiaoyan Wang   +9 more
wiley   +1 more source

A 3D GRAPHICAL MODELLING METHOD FOR HUMAN FEMUR BONE

Journal of Industrial Design and Engineering Graphics, 2006
The paper presents a method of study and the steps to obtain a virtual bone. For that purpose was used a CAD parametric software which permits to define models with a high degree of difficulty.
POPA Dragoş, GHERGHINA George, TUDOR Marin, TARNITA Daniela   +3 more
doaj