ABSTRACT The Clinical and Laboratory Standards Institute M100 document serves as a cornerstone standard for clinical microbiology laboratories in China. Maintaining the scientific rigor of its predecessors, the 36th edition incorporates updated epidemiological cutoff values, pharmacokinetic/pharmacodynamic data, and clinical efficacy evidence to revise
Kanghong Xu, Qi Wang, Hui Wang
wiley +1 more source
Overcoming multidrug resistance Acinetobacter baumanii via downregulated virulence factor genes by green fabricated silver Nanoparticles mediated Piper nigrum. [PDF]
Mahmood BS +8 more
europepmc +1 more source
Engineering Bacteria for Medicine: Delivery, Diagnosis, and Therapy
ABSTRACT With rapid advances in synthetic biology and genetic engineering, genetically engineered bacteria (GEB) have emerged as a promising platform for biological therapy, addressing key limitations of conventional drug delivery systems and demonstrating significant clinical potential.
Shiyu Xia +11 more
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Aspartyl protease MfSAP2 is a key virulence factor in mycelial form of skin fungi Malassezia furfur. [PDF]
Chua W +11 more
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Microbiome‐mediated plant‐soil feedbacks as a tool for resilient agriculture
Translating plant‐soil feedbacks (PSFs) into reliable agricultural management requires shifting from input‐dependent practices toward endogenous, process‐driven crop resilience. To bridge this gap, we propose a predictive framework centered on three strategic interventions: engineering the crop holobiont, diversifying the soil habitat, and deploying ...
Muhammad Asif +4 more
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Quorum Sensing Inhibition and Virulence Factor Attenuation in <i>Pseudomonas aeruginosa</i> by Camphor. [PDF]
Al-Helo FK +4 more
europepmc +1 more source
Given the central role of protein structures in RNA virus biology, the RNA viral protein structure database (RVPSD, https://virus.9itsg.net) integrates taxonomic classification, viral nucleotide and protein sequences, functional annotations, and predicted three‐dimensional protein structures.
Qiangzhen Yang +8 more
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Sub-Inhibitory Concentrations of Metronidazole Enhance Production, Virulence Factor Loading, and Endothelial Cytotoxicity of Porphyromonas gingivalis Extracellular Vesicles. [PDF]
Wu Z, Li X, Ge S.
europepmc +1 more source
Microbiome—pancreatic cancer crosstalk: From tumor biology to therapeutic intervention
The intratumoral microbiome acts as a critical regulator in pancreatic cancer progression and therapeutic resistance. This comprehensive review delineates the origins of pancreatic microbes, elucidates their multifaceted mechanisms in driving immune suppression, metabolic reprogramming, and stromal desmoplasia, and highlights the clinical potential of ...
Yuqin Xie +12 more
wiley +1 more source
Exploring the functional microbiome of pigs within the porcine respiratory disease complex: viral-bacterial co-infections and virulence factor profiling. [PDF]
Panattoni A +7 more
europepmc +1 more source

