Prevalence of Helicobacter pylori cagA virulence factor and validation of serological tests in a population from Northeastern Brazil. [PDF]
Freitas AC +14 more
europepmc +1 more source
Hydroxamic Acids as HDAC Inhibitor Drug Leads for Malaria
ABSTRACT Malaria is a global health threat, with an estimated 282 million cases and 610,000 malaria‐associated deaths reported in 2024. Most mortality is due to infection by Plasmodium falciparum parasites, with the highest burden occurring in Sub‐Saharan Africa.
Wisam A. Dawood +7 more
wiley +1 more source
Erratum: Global population structure of Shiga toxin-producing <i>Escherichia coli</i> O103:H2 and the variation in their major virulence factor-encoding genetic elements. [PDF]
Taniguchi I +18 more
europepmc +1 more source
Plasmepsins as Antimalarial Drug Targets—Then, Now, and the Future
ABSTRACT Malaria is a devastating disease caused by Plasmodium parasites. Plasmodium parasites express ten cathepsin D‐like aspartyl proteases, called plasmepsins (PMs). These PMs have diverse roles fulfill diverse functions throughout the parasite's lifecycle, though several exhibit functional redundancies. Among them, PMV, PMIV, and PMX are essential
Brad E. Sleebs
wiley +1 more source
<i>Pseudomonas</i> virulence factor SaxA detoxifies plant glucosinolate hydrolysis products, rescuing a commensal that suppresses virulence gene expression. [PDF]
Unger K +4 more
europepmc +1 more source
The fungal effector UvDUF1 from Ustilaginoidea virens not only promotes infection but also acts as a plant immunity elicitor, inducing broad‐spectrum disease resistance in rice and Nicotiana benthamiana. These results reveal its potential as a novel target for sustainable crop protection strategies.
Shuchen Wang +13 more
wiley +1 more source
Evolution of strain diversity and virulence factor repertoire in pediatric Staphylococcus aureus isolates. [PDF]
Free M +8 more
europepmc +1 more source
This review highlights how Phytophthora sojae utilizes unconventional lineage‐specific signaling networks, including unique G protein‐coupled receptor fusions, expanded kinases, and rapidly evolving effectors, to infect soybeans. Understanding these divergent molecular paradigms reveals critical vulnerabilities in this destructive pathogen, offering ...
Min Qiu +4 more
wiley +1 more source
Characterization of the role of putative <i>Aeromonas caviae</i>-specific virulence factor, <i>flgB,</i> in virulence and host-pathogen interactions. [PDF]
Hritzo BA, Michalski JM, Rasko DA.
europepmc +1 more source

