Surgical revision in the presence of an S. aureus infection increases virulence factor expression and activates a multi-tissue inflammatory response. [PDF]
Smith CJ +10 more
europepmc +1 more source
Targeting the intratumoral microbiota to overcome cancer immunotherapy resistance
This review delineates the mechanisms of intratumoral microbiota in cancer immunotherapy resistance, and offers strategies for microbiota‐targeted precision immunotherapy. Abstract Cancer remains a significant global health threat. The tumor microenvironment (TME) is a sophisticated ecological niche that exerts a pivotal effect on treatment outcomes ...
Bufu Tang +14 more
wiley +1 more source
Evolution of strain diversity and virulence factor repertoire in pediatric Staphylococcus aureus isolates. [PDF]
Free M +8 more
europepmc +1 more source
Integrated one‐pot CRISPR‐Cas detection: Addressing strategies and future prospects
Integrated one‐pot CRISPR‐Cas detection significantly simplifies workflows, reduces cross‐contamination risks, and shortens turnaround times, making it highly suitable for point‐of‐care testing (POCT) and resource‐limited settings. Key challenges include system compatibility issues between Cas proteins and isothermal amplification, limited multiplexing
Jian Zhou +6 more
wiley +1 more source
Assessing Virulence Factor Genes in Pig-Derived <i>Escherichia coli</i> from the Region of Vojvodina Treated with Postbiotic Substance and Herbal Essential Oils. [PDF]
Lauková A +5 more
europepmc +1 more source
Effect Probiotics on immune system modulation and wound Healing. ABSTRACT Introduction Burn wound infections caused by Acinetobacter baumannii remain a critical clinical challenge due to its extensive multidrug resistance, particularly against carbapenems.
Zeinab Fagheei Aghmiyuni +6 more
wiley +1 more source
<i>Pseudomonas</i> virulence factor SaxA detoxifies plant glucosinolate hydrolysis products, rescuing a commensal that suppresses virulence gene expression. [PDF]
Unger K +4 more
europepmc +1 more source
Microbiota‐targeted therapeutic strategies in hematological disorders. aHSCT: Transplanted immune cells from the donor may attack the recipient's tissues, especially when damage to the intestinal epithelium disrupts the gut microbiota, contributing to GVHD. Maintaining a balanced gut microbiota that supports immune regulation helps reduce GVHD risk and
Alireza Molajafari +3 more
wiley +1 more source

