Results 181 to 190 of about 13,031,687 (355)

Action of Betulinic Acid in the Inhibition of Efflux Pump NorA in Staphylococcus aureus Strains: In Vitro and In Silico Approaches

open access: yesChemistry &Biodiversity, EarlyView.
ABSTRACT Antibiotic resistance poses a serious challenge to public health, particularly in the case of Staphylococcus aureus, a Gram‐positive bacterium that employs multiple resistance mechanisms, including efflux pumps such as NorA, which extrude antimicrobial compounds from the cell and reduce antibiotic efficacy. Therefore, the search for substances
Camila Aparecida Pereira da Silva   +10 more
wiley   +1 more source

Investigating the Ligand‐Binding Properties of N‐arylbenzimidazoles as Novel Elastase Inhibitors

open access: yesChemMedChem, EarlyView.
A series of novel N‐[(3,5‐dimethylphenyl)methyl]‐1H‐benzimidazole derivatives is designed, synthesized, and evaluated for inhibitory activity against elastase. Several compounds demonstrate an antielastase activity, including the N‐(2‐bromophenyl)‐2‐(6‐chloro‐1‐(3,5‐dimethylbenzyl)‐1H‐benzo[d]imidazol‐2‐ylthio)acetamide, showing the greatest potency ...
Giovanna Pitasi   +6 more
wiley   +1 more source

Manipulation of macrophage signaling by <i>Leishmania</i> virulence factors. [PDF]

open access: yesVirulence
Gurjar D   +5 more
europepmc   +1 more source

Molecular Characterization of Virulence Factors in <i>Escherichia co</i><i>li</i> Isolated from Elderly Patients with Urinary Tract Infection [PDF]

open access: diamond
Eric Joël Tahou   +5 more
openalex   +1 more source

Sudan at War With Itself: Civilian Devastation in the Civil War

open access: yesConflict Resolution Quarterly, EarlyView.
ABSTRACT A civil war is raging in Sudan between the Sudan Armed Forces (SAF) and the Rapid Support Forces (RSF) along with militia groups. Beginning on April 15, 2023, and continuing at least to this writing (October 15, 2025), civilian noncombatants have been subjected to bombings, beatings, torture, shootings, rape, and murder on a large scale. Since
Daniel Rothbart   +3 more
wiley   +1 more source

Enemy release: loss of parasites in invasive freshwater bivalves Sinanodonta woodiana and Corbicula fluminea

open access: yesEcography, EarlyView.
Invasive freshwater bivalves harm native species, ecosystems and biodiversity, and incur economic costs. The enemy release hypothesis posits that invasive species are released from enemies during the invasion process, giving them a competitive advantage in the new environment.
Binglin Deng   +8 more
wiley   +1 more source

In Vitro Analysis of the Dynamic Role of the Bacterial Virulence Factors in Skin Wound Healing. [PDF]

open access: yesInt J Mol Sci
Hammad AS   +6 more
europepmc   +1 more source

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