Results 191 to 200 of about 14,736,402 (349)

Rhenium Complexes as Antimicrobial Agents

Helvetica Chimica Acta, EarlyView.
Rhenium complexes are stepping into the fight against superbugs. Our new review explores how these metallic complexes could inspire the next generation of antimicrobial therapies. ABSTRACT The escalating crisis of antimicrobial resistance (AMR) necessitates the exploration of unconventional therapeutic scaffolds.
Fabio Zobi, Gozde Demirci, Marija Rasic
wiley   +1 more source

Virulence factors of bovine mastitis pathogens: distribution, pathogenesis, and emerging vaccines targeting virulence factors: a literature review. [PDF]

Front Vet Sci
Li H, Wang Z, Barkema HW, Li X, Song D, Ren M, Tong J, Liu M, Gao J, Cheng J.   +9 more
europepmc   +1 more source

Antibiotic Remodeling of the Gut Microbiota Impairs Host Resistance to Secondary Infection

iMetaMed, EarlyView.
Gut microbial dynamics induced by four antibiotics, revealed distinct taxonomic and functional shifts. Vancomycin‐perturbed bacteriomes were proven to promote pathogen resistance to antibiotic treatment. Metronidazole‐treated mice showed pronounced Salmonella translocation to hepatic tissue, and altered Enterococcus avium populations modulated host ...
Miaoyu Li, Ying Chen, Xi Chen, Weili Lu, Jie Liao, Jiaqi Wang, Qiwei Liu, Yanzi Chang, Zeping Xu, Yanye Tu, Yang Zhou, Jing Xue, Binbin Wang, Kang Chen, Keyun Cheng, Chunlai Zeng, Hong Li, Qing Shen   +17 more
wiley   +1 more source

Insights into enterotoxigenic Escherichia coli diversity in Bangladesh utilizing genomic epidemiology [PDF]

, 2017
A Bankevich, A Mentzer von, A Sjoling, AC Vicente, AM Almeida de, AR Quinlan, AR Wattam, C Lindenthal, CA Jacobi, D Hernandez, DA Rasko, DA Rasko, DG Evans, DJ Ingle, EW Myers, F Canto Del, F Canto Del, F Qadri, GB Lindblom, GP Munson, H Steinsland, HL DuPont, HL DuPont, I Bolin, I Letunic, JM Fleckenstein, JM Fleckenstein, JM Fleckenstein, JS Farris, JW Sahl, JW Sahl, JW Sahl, JW Sahl, JW Sahl, K Hayashi, K Roy, K Roy, K Roy, K Schliep, KL Kotloff, LC Crossman, M So, M So, MA Lasaro, MN Price, MS Donnenberg, P Kumar, Q Luo, R Lozano, RA Finkelstein, RA Nada, RB Sack, RC Edgar, RI Walker, S Schubert, SF Altschul, SK Patel, SM Turner, T Seemann, T Wirth, TH Hazen, W Gaastra, WHO   +62 more
core   +2 more sources

Substrate Characterization of Mycobacterial Kinase PknG Revealing PknG‐KARS‐MAPK Phosphorylation Signaling Axis in Host

iMetaMed, EarlyView.
This study employed multi‐omics approaches to investigate the regulatory mechanism of Mycobacterium PknG on host cell processes. We found that host lysine‐tRNA ligase (KARS) is a potential substrate of PknG; and PknG can regulate the immune response by catalyzing the phosphorylation of KARS at T592 and T595 sites, affecting the phosphorylation level in
Nana Tian, Shuyu Xie, Yanqing Tang, Junjie Liang, Wenhan Zhu, Tianqi Liu, Yewen Sun, Yang Yang, Luoxi Zhang, Danfeng Wang, Chuyao Lin, Jinyu Jia, Minjia Tan, Jun‐Yu Xu   +13 more
wiley   +1 more source

Epidemiology, Virulence Factors, and Antibacterial Resistance of <i>Klebsiella</i> spp.: The Known Unknowns. [PDF]

Medicina (Kaunas)
Krūmiņa A, Zeltiņa I, Vikmane LM, Reinis A, Vīksna L.   +4 more
europepmc   +1 more source

Stratification of chronic rhinosinusitis with nasal polyps by distinct sinonasal microbial communities and their clinical and pathological correlations

iMetaOmics, EarlyView.
Chronic rhinosinusitis with nasal polyps (CRSwNP) is a heterogeneous inflammatory condition. Dysbiosis is commonly observed. This study identified distinct sinonasal microbial communities in CRSwNP patients and explored their clinical and pathological associations. Two distinct microbial communities were identified: community type 1 (CT1), dominated by
Bixing Fang, Yanmin Liu, Qing Bao, Lin Sun, Hexin Chen, Qingxiang Meng, Linyi Jiao, Xiaoyan Ye, Jian Li, Tao Ding, Chunwei Li   +10 more
wiley   +1 more source

<i>Aggregatibacter actinomycetemcomitans</i> virulence factors and systemic inflammation: linking periodontitis to rheumatoid arthritis. [PDF]

J Oral Microbiol
Seguel-Fuentes E, Quidel B, García-Pissani B, Duarte-Muñoz T, Bravo D, Bittner M, Schinnerling K.   +6 more
europepmc   +1 more source

Beyond “you are what you eat”: Unlocking gut microbiota‐mediated biotransformation of dietary phytochemicals

iMetaOmics, EarlyView.
The “efficacy paradox” of phytochemicals, low bioavailability yet significant health benefits, is associated with gut microbiota, which biotransforms dietary precursors into bioactive metabolites, enabling systemic effects. Thus, health outcomes of diet depend not just on intake “the rainbow”, but on gut microbial metabolism, redefining “you are what ...
Peng Yang, Ren‐You Gan
wiley   +1 more source

Quantitative proteomics of infected macrophages reveals novel Leishmania virulence factors. [PDF]

PLoS Pathog
Hagedorn N, Fradera-Sola A, Mitnacht M, Gold T, Schleicher U, Butter F, Janzen CJ.   +6 more
europepmc   +1 more source