Correlation of the virulence of Klebsiella pneumoniae K1 and K2 with the presence of a plasmid encoding aerobactin [PDF]
Xavier Nassif, Philippe Sansonetti
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Abstract Infection is a known cause of abdominal aortic aneurysm (AAA), and matrix metalloproteases‐2 (MMP‐2) secreted by vascular smooth muscle cells (SMCs) plays a key role in the structural disruption of the middle layer of the arteries during AAA progression.
Yi‐Wen Lin +6 more
wiley +1 more source
Hemolysin plasmid coding for the virulence of a nephropathogenic Escherichia coli strain [PDF]
Cees Waalwijk +3 more
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ABSTRACT The dual‐species biofilms formed by Streptococcus mutans and Candida albicans exhibit enhanced cariogenic potential due to the production of extracellular polysaccharides (EPSs). The response regulator GcrR in S. mutans negatively regulates EPS synthesis, but its impact on dual‐species biofilms remains unclear.
Bin Zhang +7 more
wiley +1 more source
Hypervirulent Klebsiella pneumoniae Sequence Type 420 with a Chromosomally Inserted Virulence Plasmid. [PDF]
Eger E +6 more
europepmc +1 more source
The ComEA/ComEC Operon is Critical for Nitrosative Stress Tolerance by an Oral Commensal
ABSTRACT Oral commensal streptococci play a large role in mediating microbial homeostasis. Our prior work has demonstrated that hydrogen peroxide (H2O2) produced by oral commensal streptococci can react with salivary nitrite (NO2) and generate peroxynitrite (ONOO−), a potent antimicrobial.
Sara E. Edmonds +3 more
wiley +1 more source
LUCID: An Integrative Approach for Target Discovery and dsRNA Design in Plant Fungal Pathogens
LUCID: A computational pipeline for RNAi‐based biofungicide design. ABSTRACT Phytopathogenic fungi pose an escalating threat to global food security and ecosystem stability, as resistance and environmental concerns diminish the effectiveness of conventional fungicides.
Lucía Jiménez‐Castro +4 more
wiley +1 more source
Insights into enterotoxigenic Escherichia coli diversity in Bangladesh utilizing genomic epidemiology [PDF]
A Bankevich +62 more
core +2 more sources
Rooting Conifer Genetic Research: An Accessible and Efficient Transformation System
ABSTRACT Conifers serve as the cornerstone of global forest ecosystems, yet their genetic transformation faces notorious challenges. To overcome the intrinsic resistance of conifer adventitious roots to Agrobacterium/Rhizobium‐mediated transformation, we systematically and iteratively engineered the binary vector by introducing chimeric Ri plasmid ...
Jing‐Jing Li +10 more
wiley +1 more source
Convergence of virulence and multidrug resistance in a single plasmid vector in multidrug-resistant Klebsiella pneumoniae ST15 [PDF]
Margaret M. C. Lam +6 more
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