Results 131 to 140 of about 6,133,142 (332)

A systems biology-driven approach to construct a comprehensive protein interaction network of influenza A virus with its host

BMC Infectious Diseases, 2020
Background Influenza A virus (IAV) infection is a serious public health problem not only in South East Asia but also in European and African countries.
Qurat ul Ain Farooq, Zeeshan Shaukat, Sara Aiman, Tong Zhou, Chunhua Li   +4 more
doaj   +1 more source

Vaccinia virus protein A46R targets multiple Toll-like-interleukin-1 receptor adaptors and contributes to virulence [PDF]

, 2005
Viral immune evasion strategies target key aspects of the host antiviral response. Recently, it has been recognized that Toll-like receptors (TLRs) have a role in innate defense against viruses.
Nathan W. Bartlett, Geoffrey L. Smith, Haga, Ismar R, Geraldine Maloney, Bowie, Andrew G., Bartlett, Nathan W., Martina Schröder, Ismar R. Haga, Haga, Ismar R., Patrick C. Reading, Andrew G. Bowie, Fitzgerald, Katherine A, Smith, Geoffrey L, Schroeder, Martina, Reading, Patrick C, Smith, Geoffrey L., Katherine A. Fitzgerald, Bartlett, Nathan W, Julianne Stack, Maloney, Geraldine, Bowie, Andrew G, Schröder, Martina, Reading, Patrick C., Stack, Julianne, Fitzgerald, Katherine A.   +24 more
core   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

FEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana, Avigail Yariv, Tal Oppenheim, Hadar Amartely, Dana Reichmann, Oded Livnah   +5 more
wiley   +1 more source

Cell surface CD11c as a neutrophil aging marker molecule

FEBS Open Bio, EarlyView.
Cell surface CD11chi neutrophils were more aged and had better phagocytic function than CD11c−/lo neutrophils. Transcriptomic analysis of CD11chi neutrophils and CD11c−/lo neutrophils in pediatric population showed that the most difference was seen in infants.
Sophia Koutsogiannaki, Fahd Alhamdan, Erik Malm, Marie Bermudez, Samuel Y. Kim, Koichi Yuki   +5 more
wiley   +1 more source

PP 1.28 – 00156 The HIV-1 antisense RNA Ast promotes viral latency via epigenetic silencing of the proviral 5′LTR and is expressed in latently infected cells from ART-suppressed donors

Journal of Virus Eradication, 2022
F. Romerio, R. Li, R. Sklutuis, J. Groebner, M. Kearney   +4 more
doaj   +1 more source

Evolution of an Eurasian avian-like influenza virus in naïve and vaccinated pigs [PDF]

, 2012
The latest human influenza pandemic highlights the ability of influenza viruses to jump species barriers and emerge in new hosts, as well as the role of pigs in generating viruses with pandemic potential.
Pablo R Murcia, Mario Caccamo, Baillie Gregory J., Gregory J. Baillie (110994), Doug Ormond (161033), Jennifer A. Mumford (161049), Grenfell Bryan T., Lloyd Lucy, Lloyd, Lucy, Battista Patrizia, Patrizia Battista, Jennifer A Mumford, Wood, James L.N., Patrizia Battista (161011), Ramirez-Gonzalez Ricardo H., Elton, Debra, Ormond Doug, Joseph Hughes (42279), Oliver Karen, Edward C. Holmes (35215), Battista, Patrizia, Holmes Edward C., Caccamo, Mario, Edward C Holmes, Wood, James L. N., Wood, James LN, Oliver, Karen, Caccamo Mario, Ricardo H Ramirez-Gonzalez, Wood James L. N., Hughes Joseph, Ricardo H. Ramirez-Gonzalez (161026), Ramirez-Gonzalez, Ricardo H., Joseph Hughes, Lucy Lloyd (161017), Murcia, Pablo R, Bryan T Grenfell, Debra Elton (29877), Ormond, Doug, Paul Kellam, Mario Caccamo (42188), Mumford Jennifer A., Murcia, Pablo R., Baillie, Gregory J., Karen Oliver, Debra Elton, Doug Ormond, Grenfell, Bryan T., Kellam Paul, Gregory J Baillie, Paul Kellam (6413), Pablo R. Murcia (111005), Murcia Pablo R., Elton Debra, Holmes, Edward C, James L. N. Wood (111001), Holmes, Edward C., Lucy Lloyd, Mumford, Jennifer A, Hughes, Joseph, Baillie, Gregory J, Mumford, Jennifer A., Karen Oliver (161040), Kellam, Paul, Grenfell, Bryan T, Ramirez-Gonzalez, Ricardo H, Bryan T. Grenfell (44234), James L N Wood   +67 more
core   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Killer Archaea: Virus-Mediated Antagonism to CRISPR-Immune Populations Results in Emergent Virus-Host Mutualism

mBio, 2020
Theory, simulation, and experimental evolution demonstrate that diversified CRISPR-Cas immunity to lytic viruses can lead to stochastic virus extinction due to a limited number of susceptible hosts available to each potential new protospacer escape ...
Samantha J. DeWerff, Maria A. Bautista, Matthew Pauly, Changyi Zhang, Rachel J. Whitaker   +4 more
doaj   +1 more source

Differential contribution of PB1-F2 to the virulence of highly pathogenic H5N1 influenza A virus in mammalian and avian species [PDF]

, 2011
Highly pathogenic avian influenza A viruses (HPAIV) of the H5N1 subtype occasionally transmit from birds to humans and can cause severe systemic infections in both hosts.
García-Sastre, Adolfo, García-Sastre, A., Rong Hai, Hale Benjamin G., Pena, Lindomar, Hai, Rong, John Steel, Manicassamy Balaji, Daniel R. Pérez, Pérez Daniel R., Manicassamy, Balaji, Pena, L., Benjamin G. Hale, Sutton, T., Zsuzsanna T Varga, Troy Sutton, Sutton Troy, Varga Zsuzsanna T., Hale, B.G., Varga, Zsuzsanna T, Pena Lindomar, Zsuzsanna T. Varga, Hale, Benjamin G, Balaji Manicassamy, Adolfo García-Sastre, Schmolke, M., Hai Rong, Hai, R., Daniel R Pérez, Pérez, D.R., Sutton, Troy, Steel, John, Pérez, Daniel R, Steel, J., Steel John, García-Sastre Adolfo, Manicassamy, B., Mirco Schmolke, Lindomar Pena, Benjamin G Hale, Schmolke, Mirco, Varga, Z.T., Schmolke Mirco   +42 more
core   +2 more sources

Influenza Vaccination Responses in Disabled Stroke Patients: A Single‐Center Prospective Observational Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study aimed to investigate the immunological response to influenza vaccination, the incidence and severity of influenza infection, and the side effects of the vaccination in patients with ischemic stroke. Methods This prospective observational study was conducted between 2023 and 2024 at Ramathibodi Hospital.
Achiraya Pakngao, Sureerat Suwatcharangoon, Pintip Ngamjanyapron, Kobporn Boonnak, Thanitta Suangtamai, Porpon Rotjanapan   +5 more
wiley   +1 more source