Cellular and Genomic Properties of Haloferax gibbonsii LR2-5, the Host of Euryarchaeal Virus HFTV1
Hypersaline environments are the source of many viruses infecting different species of halophilic euryarchaea. Information on infection mechanisms of archaeal viruses is scarce, due to the lack of genetically accessible virus–host models. Recently, a new
Colin Tittes +7 more
doaj +1 more source
Structural insights into the mechanism of archaellar rotational switching
Signal transduction via phosphorylated CheY is conserved in bacteria and archaea. In this study, the authors employ structural biochemistry combined with cell biology to delineate the mechanism of CheY recognition by the adaptor protein CheF.
Florian Altegoer +10 more
doaj +1 more source
Growth Phase Dependent Cell Shape of Haloarcula
Several haloarchaea are reported to be pleomorphic, while others exhibit remarkable shapes, such as squares. Recently, Haloferax volcanii was found to alter its morphology during growth.
Sabine Schwarzer +3 more
doaj +1 more source
Decreased MIP-3α Production from Antigen-Activated PBMCs in Symptomatic HIV-Infected Subjects
CD4+ CCR6+ T cells are highly susceptible to HIV infection, and a high cytokine producing CCR6+ T cell subset is selectively lost during HIV infection. The CCR6 chemokine MIP-3α (CCL20) is produced at sites of infection in SIV animal models. Recently, we
Fuchun Zhang +4 more
doaj +1 more source
Virus-Host Interactions during Movement Processes [PDF]
Plant viruses must invade and infect as much of their hosts as possible to maximize their chances of successful perpetuation. They move cell to cell via plasmodesmata (PD), which they modify to a greater or lesser extent, and to distant parts of the plant through the vascular system.
Boevink, Petra, Oparka, Karl J
openaire +3 more sources
On the crossroad between tolerance and posttransplant lymphoma. [PDF]
The role of the Epstein-Barr virus in the development of post-transplant lymphomas is well established. However, not all lymphomas that arise in these patients contain Epstein-Barr virus, suggesting that other cofactors are involved in tumor pathogenesis.
Nalesnik, Michael A, Starzl, Thomas E
core +1 more source
Using the nonhuman primate model of HCMV to guide vaccine development. [PDF]
The natural history of human cytomegalovirus (HCMV) is inextricably associated with mucosal surfaces. The vast preponderance of primary infections occur following mucosal exposure to infectious virions, and the high seroprevalence of HCMV throughout the ...
Barry, Peter A, Deere, Jesse D
core +3 more sources
RNA-binding protein CPEB1 remodels host and viral RNA landscapes. [PDF]
Host and virus interactions occurring at the post-transcriptional level are critical for infection but remain poorly understood. Here, we performed comprehensive transcriptome-wide analyses revealing that human cytomegalovirus (HCMV) infection results in
Aigner, Stefan +17 more
core +2 more sources
Reassessment of the capacity of the HIV-1 Env cytoplasmic domain to trigger NF-κB activation
The cytoplasmic domain of lentiviral Envelopes (EnvCD) ensures Env incorporation into nascent virions and regulates Env trafficking to and from the plasma membrane.
Cyprien Beraud +2 more
doaj +1 more source
Permissive and Restricted Virus Infection of Murine Embryonic Stem Cells [PDF]
Recent RNA interference (RNAi) studies have identified many host proteins that modulate virus infection, but small interfering RNA 'off-target' effects and the use of transformed cell lines limit their conclusiveness. As murine embryonic stem (mES) cells
Bolovan +16 more
core +1 more source

