Results 41 to 50 of about 487,341 (302)
Interferon lambda protects the female reproductive tract against Zika virus infection [PDF]
, 2019 Zika virus infections can cause devastating congenital birth defects but the underlying interactions with the host immune system are not well understood.
Arora, Nitin +7 more
core +3 more sources
Rapid feedback on hospital onset SARS-CoV-2 infections combining epidemiological and sequencing data
eLife, 2021 Background: Rapid identification and investigation of healthcare-associated infections (HCAIs) is important for suppression of SARS-CoV-2, but the infection source for hospital onset COVID-19 infections (HOCIs) cannot always be readily identified based ...
Oliver Stirrup +16 more
doaj +1 more source
EHV-1 Pathogenesis: Current in vitro Models and Future Perspectives [PDF]
, 2019 Primary infection and pathogenesis of equine herpesvirus type 1 (EHV-1) require an intricate interaction of virus with the mucosal epithelium, mononuclear cells and the vascular endothelium.
Azab, Walid +3 more
core +1 more source
Functional Landscape of African Swine Fever Virus–Host and Virus–Virus Protein Interactions
Viruses, 2023 Viral replication fully relies on the host cell machinery, and physical interactions between viral and host proteins mediate key steps of the viral life cycle.
Katarzyna Magdalena Dolata +3 more
doaj +1 more source
The SARS-coronavirus-host interactome [PDF]
, 2011 Coronaviruses (CoVs) are important human and animal pathogens that induce fatal respiratory, gastrointestinal and neurological disease. The outbreak of the severe acute respiratory syndrome (SARS) in 2002/2003 has demonstrated human vulnerability to ...
Brunn, Albrecht von +27 more
core +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Structure of the Pds5-Scc1 Complex and Implications for Cohesin Function
Cell Reports, 2016 Sister chromatid cohesion is a fundamental prerequisite to faithful genome segregation. Cohesion is precisely regulated by accessory factors that modulate the stability with which the cohesin complex embraces chromosomes.
Kyle W. Muir +5 more
doaj +1 more source
Early Virus–Host Cell Interactions
Journal of Molecular Biology, 2018 International ...
openaire +4 more sources
The Infectious Disease Ontology in the Age of COVID-19 [PDF]
, 2021 The Infectious Disease Ontology (IDO) is a suite of interoperable ontology modules that aims to provide coverage of all aspects of the infectious disease domain, including biomedical research, clinical care, and public health.
Babcock, Shane +3 more
core +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source