Results 161 to 170 of about 7,003,490 (250)

A <i>Begomovirus solanumdelhiense</i> Vector for Virus-Induced Gene Silencing in Melon. [PDF]

Pathogens
Han Y, Liao Q, Gao P, Zhang L, Wan B, Xu L, Gao S, Song Z, Dai F, Zeng R.   +9 more
europepmc   +1 more source

A cowpea severe mosaic virus-based vector simplifies virus-induced gene silencing and foreign protein expression in soybean. [PDF]

Plant Methods, 2022
Zaulda FA, Yang SH, Han J, Mlotshwa S, Dorrance A, Qu F.   +5 more
europepmc   +1 more source

Distinct Cleavage Trajectories Mediated by DNA and RNA Substrate in Argonaute From Methanocaldococcus Fervens

Advanced Science, EarlyView.
This study characterizes MfAgo, an enzyme exhibiting highly efficient DNA‐guided DNA and RNA cleavage capability. Precise RNA cleavage strictly requires dimerization to stabilize the PIWI‐loop region, while its robust DNA cleavage functions in a dimerization‐independent manner.
Fuyong Huang, Taiyu Chen, Meng Fang, Qinmiao Duanmu, Kangle Mu, Yuqi Bi, Siwei Xu, Xin Tao, Jiening Wang, Shan Wu   +9 more
wiley   +1 more source

Virus-induced gene silencing in <i>Dianthus</i> by an apple latent spherical virus vector system. [PDF]

Plant Biotechnol (Tokyo)
Tanase K, Kasajima I, Yoshikawa N.
europepmc   +1 more source

Host- and virus-induced gene silencing of HOG1-MAPK cascade genes in Rhizophagus irregularis inhibit arbuscule development and reduce resistance of plants to drought stress. [PDF]

Plant Biotechnol J, 2023
Wang S, Xie X, Che X, Lai W, Ren Y, Fan X, Hu W, Tang M, Chen H.   +8 more
europepmc   +1 more source

An Efficient Rice Virus-Induced Gene Silencing System Mediated by Wheat Dwarf Virus

The virus-induced gene silencing (VIGS) technique can effectively inhibit systemic viral infection by down-regulating plant endogenous gene expression, and it has become an important tool to study plant gene function.
Wanting Huang, Dawei Xue, Xiaowan Zhang, Xian Zhang, Lu Yu, Yijie Yan, Senzhen Zhu, Cong Dang, Yaqian Zhang   +8 more
core   +1 more source

SIRT7‐Mediated H2BK120 Succinylation Drives Aberrant Mitophagy in Sepsis‐Associated Cognitive Dysfunction

Advanced Science, EarlyView.
Sepsis triggers hippocampal SIRT7 loss, promoting histone H2B succinylation and activation of the PD‐1/PD‐L1–PINK1 axis. This metabolic‐epigenetic cascade drives aberrant mitophagy and neuronal injury, ultimately causing cognitive deficits. Targeting SIRT7‐dependent succinylation offers a potential strategy to protect brain function during sepsis ...
Na Meng, Jiateng Zhou, Xiaoyu Guo, Ting Hong, Xuelian Li, Xingyu Wei, Chanhua Zhang, Xixue Zhang, Songbin Liu, Yulin Zhang, Liangfang Yao, Lina Huang, Weidong Gu   +12 more
wiley   +1 more source

Targeted disruption of vacuolar-sorting protein and inhibitor of apoptosis genes via virus-induced gene silencing alters survival and reproduction of Diaphorina citri. [PDF]

Pest Manag Sci
Killiny N, Rashidi M, Shilts T, Stelinski LL, Bonning BC.   +4 more
europepmc   +1 more source

Virus-induced gene silencing as a tool for functional studies in Cleome violacea. [PDF]

Appl Plant Sci, 2021
Carey S, Higuera-Díaz M, Mankowski P, Rocca A, Hall JC.   +4 more
europepmc   +1 more source

Multifunctional Nanovaccine‐Radiotherapy Synergy Drives Anti‐Tumor Immunity via Multi‐Cascade Cell Death for Pancreatic Cancer Therapy

Advanced Science, EarlyView.
Machine‐learning‐driven transcriptomic analysis identifies FSTL3 as a key tumor‐microenvironment regulator in desmoplastic pancreatic adenocarcinoma. A cRGD‐modified liposome co‐loading gemcitabine and siFSTL3 serves as an irradiation‐triggered in situ nanovaccine. It synergizes with radiotherapy to induce ferroptosis and immunogenic cell death through
Chengyi Huang, Yushu Han, Xiang Liu, Chuanhao Wang, Xiaofei Zhu, Di Chen, Yangyang Gong, Liang Chen, Wenjuan Chen, Zhenyuan Miao, Bufu Tang, Huojun Zhang   +11 more
wiley   +1 more source