Results 91 to 100 of about 6,229,730 (383)

Analysis of Zika virus capsid-Aedes aegypti mosquito interactome reveals pro-viral host factors critical for establishing infection

Nature Communications, 2021
Here the authors develop mosquito cell lines expressing Zika virus (ZIKV) capsid and perform proteomics experiments retrieving 157 protein interactors, of which they show 8 to act as pro-viral factors, showing the transitional endoplasmic reticulum 94 ...
Rommel J. Gestuveo, Jamie Royle, Claire L. Donald, Douglas J. Lamont, Edward C. Hutchinson, Andres Merits, Alain Kohl, Margus Varjak   +7 more
doaj   +1 more source

Emergence of a novel swine-origin influenza A (H1N1) virus in humans.

New England Journal of Medicine, 2009
BACKGROUND On April 15 and April 17, 2009, novel swine-origin influenza A (H1N1) virus (S-OIV) was identified in specimens obtained from two epidemiologically unlinked patients in the United States.
F. Dawood, Seemalata Jain, L. Finelli, M. Shaw, S. Lindstrom, R. Garten, L. Gubareva, Xiyan Xu, C. Bridges, T. Uyeki   +9 more
semanticscholar   +1 more source

Evolutionary interplay between viruses and R‐loops

FEBS Letters, EarlyView.
Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi, Zita Képes, Zoltán Szabó, Eszter Csoma, Lóránt Székvölgyi   +4 more
wiley   +1 more source

Boraceia Virus. A New Virus Related to Anopheles B Virus.

Experimental Biology and Medicine, 1966
SummaryBoraceia virus, a new arbovirus isolated from Anopheles (K.) cruzii, is described. Serological cross-reactions between Boraceia and Anopheles B virus were demonstrated. It is proposed that these viruses form a new arbovirus antigenic group, the Anopheles B group.The authors are indebted to Miss Amelia H. P. Andrade and Dr. Robert E.
Lia De Abreu Sacchetta, O. de Souza Lopes, I. E. M. Fonseca, Oswaldo Paulo Forattini, J. P. G. Lacerda, Ernesto Xavier Rabello   +5 more
openaire   +3 more sources

GLUE: a flexible software system for virus sequence data

BMC Bioinformatics, 2018
Background Virus genome sequences, generated in ever-higher volumes, can provide new scientific insights and inform our responses to epidemics and outbreaks.
Joshua B. Singer, Emma C. Thomson, John McLauchlan, Joseph Hughes, Robert J. Gifford   +4 more
doaj   +1 more source

Experiences of diagnosis, stigma, culpability, and disclosure in male patients with hepatitis C virus: an interpretative phenomenological analysis [PDF]

, 2019
The current study aimed to explore the lived experience of patients with hepatitis C virus infection. Semi-structured interviews were conducted with seven male participants living with hepatitis C virus and were analysed using interpretative ...
Adele Dickson, Anna Krzeczkowska, Hopwood M, Lowe D, Paul Flowers, Peter Hayes, Poynard T, Smith JA, Stuenkel D, Tompkins CNE, Wasley A, Zoe Chouliara   +11 more
core   +3 more sources

Circulating histones as clinical biomarkers in critically ill conditions

FEBS Letters, EarlyView.
Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez, Juan Carlos Ruiz‐Rodríguez, Ricard Ferrer, Raquel Durá, Antonio Artigas, Iván Bajaña, David Bolado López de Andujar, Irene Cánovas‐Cervera, Adrián Ceccato, Luis Chiscano‐Camón, Elena Climent‐Martinez, Georgia García Fernández, Gemma Goma, Verónica Monforte, Beatriz Quevedo‐Sánchez, Adolf Ruiz‐Sanmartín, Antonio Sierra‐Rivera, Nieves Carbonell Monleón   +17 more
wiley   +1 more source

First report of autochthonous transmission of Zika virus in Brazil

Memórias do Instituto Oswaldo Cruz, 2015
In the early 2015, several cases of patients presenting symptoms of mild fever, rash, conjunctivitis and arthralgia were reported in the northeastern Brazil.
C. Zanluca, Vanessa Campos Andrade de Melo, A. L. Mosimann, Glauco Igor Viana dos Santos, C. D. D. dos Santos, K. Luz   +5 more
semanticscholar   +1 more source

‘It’s been a long haul, a big haul, but we’ve made it’: hepatitis C virus treatment in post-transplant patients with virus recurrence: An interpretative phenomenological analysis [PDF]

, 2018
The lived experience of both interferon-based and new interferon-free treatments in patients with hepatitis C virus remains understudied. To explore their journey through hepatitis C virus treatment, we interviewed seven post-transplant patients with ...
Chouliara, Zoe, Dickson, Adele, Flowers, Paul, Hayes, Peter, Krzeczkowska, Anna   +4 more
core   +3 more sources

Insights into pegRNA design from editing of the cardiomyopathy‐associated phospholamban R14del mutation

FEBS Letters, EarlyView.
This study reveals how prime editing guide RNA (pegRNA) secondary structure and reverse transcriptase template length affect prime editing efficiency in correcting the phospholamban R14del cardiomyopathy‐associated mutation. Insights support the design of structurally optimized enhanced pegRNAs for precise gene therapy.
Bing Yao, Qiangbing Yang, Christian J.B. Snijders Blok, Mark A. Daniels, Pieter A. Doevendans, Raymond Schiffelers, Joost P.G. Sluijter, Zhiyong Lei   +7 more
wiley   +1 more source