Results 91 to 100 of about 6,298,490 (383)

Boraceia Virus. A New Virus Related to Anopheles B Virus.

Experimental Biology and Medicine, 1966
SummaryBoraceia virus, a new arbovirus isolated from Anopheles (K.) cruzii, is described. Serological cross-reactions between Boraceia and Anopheles B virus were demonstrated. It is proposed that these viruses form a new arbovirus antigenic group, the Anopheles B group.The authors are indebted to Miss Amelia H. P. Andrade and Dr. Robert E.
Lia De Abreu Sacchetta, O. de Souza Lopes, I. E. M. Fonseca, Oswaldo Paulo Forattini, J. P. G. Lacerda, Ernesto Xavier Rabello   +5 more
openaire   +3 more sources

Cyclic nucleotide signaling as a drug target in retinitis pigmentosa

FEBS Letters, EarlyView.
Disruptions in cGMP and cAMP signaling can contribute to retinal dysfunction and photoreceptor loss in retinitis pigmentosa. This perspective examines the mechanisms and evaluates emerging evidence on targeting these pathways as a potential therapeutic strategy to slow or prevent retinal degeneration.
Katri Vainionpää, Ahmed B. Montaser, Henri Leinonen   +2 more
wiley   +1 more source

Uncovering the viral aetiology of undiagnosed acute febrile illness in Uganda using metagenomic sequencing

Nature Communications
Viruses associated with acute febrile illness in Africa cause a spectrum of clinical disease from mild to life-threatening. Routine diagnostic methods are insufficient to identify all viral pathogens in this region.
Shirin Ashraf, Hanna Jerome, Daniel Lule Bugembe, Deogratius Ssemwanga, Timothy Byaruhanga, John Timothy Kayiwa, Robert Downing, Jesus F. Salazar-Gonzalez, Maria G. Salazar, James G. Shepherd, Craig Wilkie, Chris Davis, Nicola Logan, Sreenu B. Vattipally, Gavin S. Wilkie, Ana da Silva Filipe, Alfred Ssekagiri, Prossy Namuwulya, Henry Bukenya, Brian K. Kigozi, Weronika Witkowska McConnell, Brian J. Willett, Stephen Balinandi, Julius Lutwama, Pontiano Kaleebu, Josephine Bwogi, Emma C. Thomson   +26 more
doaj   +1 more source

The Timing and Magnitude of the Type I Interferon Response Are Correlated with Disease Tolerance in Arbovirus Infection

mBio, 2023
Infected hosts possess two alternative strategies to protect themselves against the negative impact of virus infections: resistance, used to abrogate virus replication, and disease tolerance, used to avoid tissue damage without controlling viral burden ...
Alexandra Hardy, Siddharth Bakshi, Wilhelm Furnon, Oscar MacLean, Quan Gu, Margus Varjak, Mariana Varela, Muhamad Afiq Aziz, Andrew E. Shaw, Rute Maria Pinto, Natalia Cameron Ruiz, Catrina Mullan, Aislynn E. Taggart, Ana Da Silva Filipe, Richard E. Randall, Sam J. Wilson, Meredith E. Stewart, Massimo Palmarini   +17 more
doaj   +1 more source

Computing with viruses [PDF]

, 2016
In recent years, different computing models have emerged within the area of Unconven-tional Computation, and more specifically within Natural Computing, getting inspiration from mechanisms present in Nature.
Chen, Xu, Pérez Jiménez, Mario de Jesús, Valencia Cabrera, Luis, Wang, Beizhan, Zeng, Xiangxiang   +4 more
core   +1 more source

TRAF2 binds to TIFA via a novel motif and contributes to its autophagic degradation

FEBS Letters, EarlyView.
TRAF family members couple receptor signalling complexes to downstream outputs, but how they interact with these complexes is not always clear. Here, we show that during ADP‐heptose signalling, TRAF2 binding to TIFA requires two short sequence motifs in the C‐terminal tail of TIFA, which are distinct from the TRAF6 binding motif.
Tom Snelling, Kodi Hunter, Celest W. S. Tay, Nicola T. Wood, Philip Cohen   +4 more
wiley   +1 more source

First report of autochthonous transmission of Zika virus in Brazil

Memórias do Instituto Oswaldo Cruz, 2015
In the early 2015, several cases of patients presenting symptoms of mild fever, rash, conjunctivitis and arthralgia were reported in the northeastern Brazil.
C. Zanluca, Vanessa Campos Andrade de Melo, A. L. Mosimann, Glauco Igor Viana dos Santos, C. D. D. dos Santos, K. Luz   +5 more
semanticscholar   +1 more source

The epithelial barrier theory proposes a comprehensive explanation for the origins of allergic and other chronic noncommunicable diseases

FEBS Letters, EarlyView.
Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu, Huseyn Babayev, Ismail Ogulur, Sena Ardicli, Yagiz Pat, Duygu Yazici, Bingjie Zhao, Lihong Chang, Xiaoqing Liu, Paolo D'Avino, Manru Li, Ceren Biçer, Fatma Hacer Kurtoğlu Babayev, Raja Dhir, Kari C. Nadeau, Marie‐Charlotte Brüggen, Mubeccel Akdis, Cezmi A. Akdis   +17 more
wiley   +1 more source

Genetic Methods to Identify and Manipulate Newly born Neurons in the Adult Brain

Frontiers in Neuroscience, 2011
Although mammalian neurogenesis is mostly completed by the perinatal period, new neurons are continuously generated in the subventricular zone of the lateral ventricle and the subgranular zone of the hippocampal dentate gyrus.
Itaru eImayoshi, Masayuki eSakamoto, Ryoichiro eKageyama   +2 more
doaj   +1 more source

Analysis of Zika virus capsid-Aedes aegypti mosquito interactome reveals pro-viral host factors critical for establishing infection

Nature Communications, 2021
Here the authors develop mosquito cell lines expressing Zika virus (ZIKV) capsid and perform proteomics experiments retrieving 157 protein interactors, of which they show 8 to act as pro-viral factors, showing the transitional endoplasmic reticulum 94 ...
Rommel J. Gestuveo, Jamie Royle, Claire L. Donald, Douglas J. Lamont, Edward C. Hutchinson, Andres Merits, Alain Kohl, Margus Varjak   +7 more
doaj   +1 more source