Results 71 to 80 of about 2,705,124 (318)

Emergence of measles virus genotype D8 amidst endemic B3 circulation in Uganda, 2023-2025

International Journal of Infectious Diseases
Objectives: Measles remains a significant global health threat, with recurrent outbreaks, even in regions such as America, where the disease had been eliminated.
Prossy Namuwulya, Irene Turyahabwe, Rena Nakyeyune, Molly Birungi, Phionah Tushabe, James Peter Eliku, Francis Aine, Jonathan Comfort Haumba, Mathias Ssenono, Lucy Nakabazzi, Maria Nabbuto, Jacob Mpiima, Micheal Baganizi, Immaculate Ampeire, Annet Kisakye, Qouilazoni Aquino Ukuli, Henry Bukenya, Josephine Bwogi, Barnabas Bakamutumaho   +18 more
doaj   +1 more source

Effect of Coated Silver Nanoparticles on Cancerous vs. Healthy Cells

Journal of Toxicology, 2022
Unique properties of silver nanoparticles (NPs) ensure their wide applications, in biomedicine; for this reason, it is very important carefully to study the toxicity of such NPs. The influence of silver nanoparticles coated with natural resin (Ag NPs) on
Liubov Artiukh, Olga Povnitsa, Svitlana Zahorodnia, Calin V. Pop, Nodari Rizun   +4 more
doaj   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Activation of the beta interferon promoter by paramyxoviruses in the absence of virus protein synthesis [PDF]

, 2012
Conflicting reports exist regarding the requirement for virus replication in interferon (IFN) induction by paramyxoviruses. Our previous work has demonstrated that pathogen-associated molecular patterns capable of activating the IFN-induction cascade are
Killip, M. J., Randall, RE, Goodbourn, S., Precious, BL, Young, D. F., Precious, B. L., Randall, R. E., S. Goodbourn, Goodbourn, S, D. F. Young, R. E. Randall, M. J. Killip, Young, DF, Killip, MJ, B. L. Precious   +14 more
core   +1 more source

Uncovering the viral aetiology of undiagnosed acute febrile illness in Uganda using metagenomic sequencing

Nature Communications
Viruses associated with acute febrile illness in Africa cause a spectrum of clinical disease from mild to life-threatening. Routine diagnostic methods are insufficient to identify all viral pathogens in this region.
Shirin Ashraf, Hanna Jerome, Daniel Lule Bugembe, Deogratius Ssemwanga, Timothy Byaruhanga, John Timothy Kayiwa, Robert Downing, Jesus F. Salazar-Gonzalez, Maria G. Salazar, James G. Shepherd, Craig Wilkie, Chris Davis, Nicola Logan, Sreenu B. Vattipally, Gavin S. Wilkie, Ana da Silva Filipe, Alfred Ssekagiri, Prossy Namuwulya, Henry Bukenya, Brian K. Kigozi, Weronika Witkowska McConnell, Brian J. Willett, Stephen Balinandi, Julius Lutwama, Pontiano Kaleebu, Josephine Bwogi, Emma C. Thomson   +26 more
doaj   +1 more source

Nonhomologous Recombination between Defective Poliovirus and Coxsackievirus Genomes Suggests a New Model of Genetic Plasticity for Picornaviruses

mBio, 2014
Most of the circulating vaccine-derived polioviruses (cVDPVs) implicated in poliomyelitis outbreaks in Madagascar have been shown to be recombinants between the type 2 poliovirus (PV) strain of the oral polio vaccine (Sabin 2) and another species C human
Barbara Holmblat, Sophie Jégouic, Claire Muslin, Bruno Blondel, Marie-Line Joffret, Francis Delpeyroux   +5 more
doaj   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

FEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Evidence of viral adaptation to HLA class I-restricted immune pressure in chronic hepatitis C virus infection [PDF]

, 2006
Cellular immune responses are an important correlate of hepatitis C virus (HCV) infection outcome. These responses are governed by the host's human leukocyte antigen (HLA) type, and HLA-restricted viral escape mutants are a critical aspect of this host ...
Cheng, Wendy, Battegay, Manuel, E. Freitas, Weber, R., Furrer, H., Jeffrey, G., James, Ian, Park, Lawrence P, Swiss HIV Cohort Study,, G. Jeffrey, Battegay, M., Jeffrey, Gary, Herrmann, S., James, I., Weber, R., Battegay, M., Chapman, R., S. Herrmann, Furrer, Hansjakob, Telenti, Amalio, Freitas, E., Telenti, A., Lucas, M., M. Lucas, null null, I. James, Weber, Rainer, Telenti, A., Lucas, M., Freitas, Elizabeth, H. Furrer, Cheng, W., Jeffrey, G., Gaudieri, S., S. A. Mallal, Park, P., Freitas, E., Cheng, W., K. Pfafferott, Pfafferott, K., S. Gaudieri, R. Weber, Naidoo, Kiloshni, A. Rauch, Pfafferott, K., Mallal, Simon A, L. P. Park, Rauch, A., Chapman, R., A. Telenti, Pfafferott, Katja, R. Chapman, Lucas, Michaela, M. Battegay, Park, L.P., Naidoo, K., Herrmann, Susan, K. Naidoo, Furrer, H., Rauch, Andri, Park, L. P., W. Cheng, Herrmann, S., Naidoo, K., Chapman, Russell, Rauch, A., Mallal, S.A., Gaudieri, S., Mallal, S. A., James, I., Gaudieri, Silvana   +70 more
core   +2 more sources

GLUE: a flexible software system for virus sequence data

BMC Bioinformatics, 2018
Background Virus genome sequences, generated in ever-higher volumes, can provide new scientific insights and inform our responses to epidemics and outbreaks.
Joshua B. Singer, Emma C. Thomson, John McLauchlan, Joseph Hughes, Robert J. Gifford   +4 more
doaj   +1 more source

Epidemiology and biology of a herpesvirus in rabies endemic vampire bat populations

Nature Communications, 2020
Here, Griffiths et al. show infection of 80–100% of sampled vampire bats in Peru with a newly discovered betaherpesvirus (DrBHV) that exhibits specificity within neotropical bats and evidence for superinfection.
Megan E. Griffiths, Laura M. Bergner, Alice Broos, Diana K. Meza, Ana da Silva Filipe, Andrew Davison, Carlos Tello, Daniel J. Becker, Daniel G. Streicker   +8 more
doaj   +1 more source