Results 81 to 90 of about 2,627,962 (316)

Delivery of ALX-0171 by inhalation greatly reduces respiratory syncytial virus disease in newborn lambs [PDF]

, 2018
Alejandro Larios Mora, Laurent Detalle, Jack M. Gallup, Albert Van Geelen, Thomas Stöhr, Linde Duprez, Mark R. Ackermann   +6 more
openalex   +1 more source

Antiviral Potential of Azelastine against Major Respiratory Viruses [PDF]

, 2023
Katrin Fischhuber, Zoltán Bánki, Janine Kimpel, Natalie Kragl, Annika Rössler, Annika Bolze, Brigitte Muellauer, Joachim Angerer, Gábor Nagy, Eszter Nagy, Valéria Szijártó   +10 more
openalex   +1 more source

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

Thirteen-Year Sequelae of Marburg Virus Disease Survival: Persistent Cardiometabolic, Immunometabolic, and Haematological Alterations in the Absence of Psychological Morbidity

Pathogens
Background: Marburg virus disease (MVD) is a highly lethal filoviral infection, yet its long-term health consequences remain poorly understood. We present one of the most temporally distant evaluations of MVD survivors, conducted 13 years post-outbreak ...
Jennifer Serwanga, Raymond Ernest Kaweesa, Joseph Katende Ssebwana, Goeffrey Odoch, Raymond Reuel Wayesu, Anne Daphine Ntabadde, Deborah Mukisa, Peter Ejou, FiloStudy Team, Julius Julian Lutwama, Pontiano Kaleebu   +10 more
doaj   +1 more source

Structural insights into the mechanism and evolution of the vaccinia virus mRNA cap N7 methyl‐transferase [PDF]

, 2007
Marcos de la Peña, O.J.P. Kyrieleis, S. Cusack   +2 more
openalex   +1 more source

Interplay between RNA‐protein interactions and RNA structures in gene regulation

FEBS Open Bio, EarlyView.
Methodological advances in mapping transcriptome‐wide RNA‐protein interactions and RNA structures have started to uncover the potential of RNP conformations in gene regulation. Competing RNA–RNA, RNA‐protein and protein–protein interactions shape the compaction and function of RNPs throughout their lifetime and may provide novel therapeutic targets in ...
Jenni Rapakko, Mauro Scaravilli, Minna‐Liisa Änkö   +2 more
wiley   +1 more source

Viro3D: a comprehensive database of virus protein structure predictions

Molecular Systems Biology
Viruses are genetic parasites of cellular life. Tolerance to genetic change, high mutation rates, adaptations to hosts, and immune escape have driven extensive sequence divergence of viral genes, hampering phylogenetic inference and functional annotation.
Ulad Litvin, Spyros Lytras, Alexander Jack, David L Robertson, Joseph Hughes, Joe Grove   +5 more
doaj   +1 more source

Circulating Avian Influenza Viruses Closely Related to the 1918 Virus Have Pandemic Potential [PDF]

, 2014
Tokiko Watanabe, Gongxun Zhong, Colin A. Russell, Noriko Nakajima, Masato Hatta, Anthony Hanson, Ryan McBride, David F. Burke, Kenta Takahashi, Satoshi Fukuyama, Yuriko Tomita, Eileen A. Maher, Shinji Watanabe, Masaki Imai, Gabriele Neumann, Hideki Hasegawa, James C. Paulson, Derek J. Smith, Yoshihiro Kawaoka   +18 more
openalex   +1 more source

Overexpression of CDT1 inhibits cell cycle progression at S phase by interacting with the mini‐chromosome maintenance complex and causes DNA damage

FEBS Open Bio, EarlyView.
CDT1 is an essential protein for DNA replication licensing that loads the MCM complex, the eukaryotic replicative DNA helicase, onto replication origins. Overexpression of CDT1 induces cell cycle arrest at the S phase. Here we showed CDT1 inhibits the progression of replication forks by interacting with the MCM complex, leading to the stalling and ...
Takashi Tsuyama, Nonoka Takayama, Rina Tanaka, Yuuki Arai, Yohko Yamaguchi, Yuko Nawata, Yutaro Azuma, Shusuke Tada   +7 more
wiley   +1 more source

Navigating Virology’s Frontiers in Africa: Global Virus Network 2024 Durban Meeting

Viruses
The Global Virus Network (GVN) is a voluntary consortium of virology laboratories and affiliated scientists that seek to prevent and control global viral threats.
Maggie L. Bartlett, Rubeshan Perumal, Sten H. Vermund, Salim Abdool Karim   +3 more
doaj   +1 more source