Results 1 to 10 of about 6,218 (268)
Hepatitis C Virus Assembly Imaging [PDF]
Viruses, 2011 Hepatitis C Virus (HCV) assembly process is the least understood step in the virus life cycle. The functional data revealed by forward and reverse genetics indicated that both structural and non-structural proteins are involved in the assembly process ...
Costin-Ioan Popescu +2 more
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Frontiers in Microbiology, 2021 Flavivirus envelope protein (E) plays an important role in cellular infection, especially in virulence and antigenicity. E domain III of Tembusu virus (TMUV) is highly conserved among flaviviruses and contains four loop regions. However, the functions of
Tao Hu +50 more
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Rotavirus Particle Disassembly and Assembly In Vivo and In Vitro
Viruses, 2023 Rotaviruses (RVs) are non-enveloped multilayered dsRNA viruses that are major etiologic agents of diarrheal disease in humans and in the young in a large number of animal species.
Dunia Asensio-Cob +2 more
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Viruses, 2021 The assembly of a hexameric lattice of retroviral immature particles requires the involvement of cell factors such as proteins and small molecules. A small, negatively charged polyanionic molecule, myo-inositol hexaphosphate (IP6), was identified to ...
Alžběta Dostálková +5 more
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Mechanisms of Virus Assembly [PDF]
Annual Review of Physical Chemistry, 2015 Viruses are nanoscale entities containing a nucleic acid genome encased in a protein shell called a capsid and in some cases are surrounded by a lipid bilayer membrane. This review summarizes the physics that govern the processes by which capsids assemble within their host cells and in vitro.
Jason D. Perlmutter, Michael F. Hagan
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Tetraspanin Assemblies in Virus Infection [PDF]
Frontiers in Immunology, 2018 Tetraspanins (Tspans) are a family of four-span transmembrane proteins, known as plasma membrane "master organizers." They form Tspan-enriched microdomains (TEMs or TERMs) through lateral association with one another and other membrane proteins. If multiple microdomains associate with each other, larger platforms can form.
Florin, Luise, Lang, Thorsten
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Electrostatics and the assembly of an RNA virus [PDF]
Physical Review E, 2005 Electrostatic interactions play a central role in the assembly of single-stranded RNA viruses. Under physiological conditions of salinity and acidity, virus capsid assembly requires the presence of genomic material that is oppositely charged to the core proteins. In this paper we apply basic polymer physics and statistical mechanics methods to the self-
Paul van der Schoot, Robijn Bruinsma
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Viruses, 2020 Marburg virus (MARV) is a lipid-enveloped negative sense single stranded RNA virus, which can cause a deadly hemorrhagic fever. MARV encodes seven proteins, including VP40 (mVP40), a matrix protein that interacts with the cytoplasmic leaflet of the host ...
Kaveesha J. Wijesinghe +7 more
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Exploring the Paths of (Virus) Assembly [PDF]
Biophysical Journal, 2010 Assembly of viruses that have hundreds of subunits or folding of proteins that have hundreds of amino acids-complex biological reactions-are often spontaneous and rapid. Here, we examine the complete set of intermediates available for the assembly of a hypothetical viruslike particle and the connectivity between these intermediates in a graph-theory ...
Adam Zlotnick +3 more
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Y-Box Binding Protein 1 Interacts with Dengue Virus Nucleocapsid and Mediates Viral Assembly
mBio, 2022 Infection with dengue virus (DENV) induces vast rearrangements of the endoplasmic reticulum, which allows the compartmentalization of viral RNA replication and particle assembly. Both processes occur in concert with viral and cellular proteins.
Mayra Diosa-Toro +5 more
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