Results 11 to 20 of about 243,139 (310)

Hepatitis C Virus Assembly Imaging [PDF]

open access: yesViruses, 2011
Hepatitis C Virus (HCV) assembly process is the least understood step in the virus life cycle. The functional data revealed by forward and reverse genetics indicated that both structural and non-structural proteins are involved in the assembly process ...
Costin-Ioan Popescu   +2 more
doaj   +3 more sources

Mechanisms of Virus Assembly [PDF]

open access: yesAnnual Review of Physical Chemistry, 2015
Viruses are nanoscale entities containing a nucleic acid genome encased in a protein shell called a capsid and in some cases are surrounded by a lipid bilayer membrane. This review summarizes the physics that govern the processes by which capsids assemble within their host cells and in vitro.
Perlmutter, Jason D, Hagan, Michael F
openaire   +3 more sources

Tetraspanin Assemblies in Virus Infection [PDF]

open access: yesFrontiers in Immunology, 2018
Tetraspanins (Tspans) are a family of four-span transmembrane proteins, known as plasma membrane "master organizers." They form Tspan-enriched microdomains (TEMs or TERMs) through lateral association with one another and other membrane proteins. If multiple microdomains associate with each other, larger platforms can form.
Florin, Luise, Lang, Thorsten
openaire   +4 more sources

Three-Dimensional Investigations of Virus-Associated Structures in the Nuclei with White Spot Syndrome Virus (WSSV) Infection in Red Swamp Crayfish (Procambarus clarkii)

open access: yesAnimals, 2022
White spot syndrome virus (WSSV) has been reported to cause severe economic loss in the shrimp industry. With WSSV being a large virus still under investigation, the 3D structure of its assembly remains unclear.
Yovita Permata Budi   +4 more
doaj   +1 more source

Assembly and Capsid Expansion Mechanism of Bacteriophage P22 Revealed by High-Resolution Cryo-EM Structures

open access: yesViruses, 2023
The formation of many double-stranded DNA viruses, such as herpesviruses and bacteriophages, begins with the scaffolding-protein-mediated assembly of the procapsid. Subsequently, the procapsid undergoes extensive structural rearrangement and expansion to
Hao Xiao   +7 more
doaj   +1 more source

The interaction between herpes simplex virus 1 genome and promyelocytic leukemia nuclear bodies (PML-NBs) as a hallmark of the entry in latency

open access: yesMicrobial Cell, 2016
Herpes simplex virus 1 (HSV-1) is a human pathogen that establishes latency in the nucleus of infected neurons in the PNS and the CNS. At the transcriptional level latency is characterized by a quasi-complete silencing of the extrachromosomal viral ...
Patrick Lomonte
doaj   +1 more source

Efficient support of virus-like particle assembly by the HIV-1 packaging signal

open access: yeseLife, 2018
The principal structural component of a retrovirus particle is the Gag protein. Retroviral genomic RNAs contain a ‘packaging signal’ (‘Ψ') and are packaged in virus particles with very high selectivity.
Mauricio Comas-Garcia   +5 more
doaj   +1 more source

The curious case of genome packaging and assembly in RNA viruses infecting plants

open access: yesFrontiers in Genetics, 2023
Genome packaging is the crucial step for maturation of plant viruses containing an RNA genome. Viruses exhibit a remarkable degree of packaging specificity, despite the probability of co-packaging cellular RNAs.
Tushar Ranjan   +9 more
doaj   +1 more source

Dual Role of a Viral Polymerase in Viral Genome Replication and Particle Self-Assembly

open access: yesmBio, 2018
Double-stranded RNA (dsRNA) viruses package several RNA-dependent RNA polymerases (RdRp) together with their dsRNA genome into an icosahedral protein capsid known as the polymerase complex.
Xiaoyu Sun   +3 more
doaj   +1 more source

Distinct Pathway of Human T-Cell Leukemia Virus Type 1 Gag Punctum Biogenesis Provides New Insights into Enveloped Virus Assembly

open access: yesmBio, 2018
The assembly of virus particles is a crucial aspect of virus spread. For retroviruses, the Gag polyprotein is the key driver for virus particle assembly.
John P. Eichorst   +3 more
doaj   +1 more source

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