Virotherapy in Germany—Recent Activities in Virus Engineering, Preclinical Development, and Clinical Studies [PDF]
Viruses, 2021 Virotherapy research involves the development, exploration, and application of oncolytic viruses that combine direct killing of cancer cells by viral infection, replication, and spread (oncolysis) with indirect killing by induction of anti-tumor immune ...
Dirk M. Nettelbeck +27 more
doaj +4 more sources
Virus Engineering and Applications. [PDF]
Int J Mol Sci, 2023 This Special Issue highlights multiple facets of virus engineering, ranging from the dissection of the biological properties of individual viral functions in the context of safe genomic backbones, virus genetic modification for applications in gene therapy, oncolytic virotherapy and vaccine production, to the hurdles presented by quality control and ...
Menotti L.
europepmc +4 more sources
Oncolytic Virus Engineering and Utilizations: Cancer Immunotherapy Perspective [PDF]
Viruses, 2023 Oncolytic viruses have positively impacted cancer immunotherapy over the past 20 years. Both natural and genetically modified viruses have shown promising results in treating various cancers.
Palaniyandi Muthukutty, So Young Yoo
doaj +2 more sources
Strategies for Engineering Virus Resistance in Potato
Plants, 2023 Potato (Solanum tuberosum L.) is an important vegetable crop that plays a pivotal role in the world, especially given its potential to feed the world population and to act as the major staple food in many developing countries.
Jiecai Liu +6 more
doaj +3 more sources
DNA Engineering and Hepatitis B Virus Replication [PDF]
Frontiers in Microbiology, 2021 Recombinant DNA technology is a vital method in human hepatitis B virus (HBV), producing reporter viruses or vectors for gene transferring. Researchers have engineered several genes into the HBV genome for different purposes; however, a systematic ...
Chun-yang Gan +5 more
doaj +3 more sources
Engineering Maize rayado fino virus for virus‐induced gene silencing [PDF]
Plant Direct, 2020 Maize rayado fino virus (MRFV) is the type species of the genus Marafivirus in the family Tymoviridae. It infects maize (Zea mays), its natural host, to which it is transmitted by leafhoppers including Dalbulus maidis and Graminella nigrifrons in a ...
Sizolwenkosi Mlotshwa +5 more
doaj +3 more sources
Plant Virus-Derived Vectors for Plant Genome Engineering
Viruses, 2023 Advances in genome engineering (GE) tools based on sequence-specific programmable nucleases have revolutionized precise genome editing in plants. However, only the traditional approaches are used to deliver these GE reagents, which mostly rely on ...
Muhammad Arslan Mahmood +4 more
doaj +3 more sources
A rapid detection of Nipah virus nucleocapsid antigen in inactivated viral cultures [PDF]
Emerging Microbes and InfectionsNipah virus (NiV) is a highly lethal zoonotic henipavirus that causes severe respiratory disease and encephalitis and remains a priority pathogen for outbreak preparedness.
Gyeongmu Choi +17 more
doaj +2 more sources
Adeno-Associated Virus Engineering and Load Strategy for Tropism Modification, Immune Evasion and Enhanced Transgene Expression. [PDF]
Int J NanomedicineZhou X +8 more
europepmc +2 more sources
Construction and Rescue of a Rabies Virus with Duplicated Glycoprotein Gene
Vaccine Research, 2021 Introduction: Rabies is almost always fatal but entirely preventable through proper vaccination. Inadequacy of costly high-quality cell culture vaccines is sometimes a bottleneck for expanded rabies control plans.
Ashkan Alamdary +3 more
doaj +1 more source