Results 11 to 20 of about 218,144 (258)

ORACLE reveals a bright future to fight bacteria

eLife, 2021
A new way to alter the genome of bacteriophages helps produce large libraries of variants, allowing these bacteria-killing viruses to be designed to target species harmful to human health.
Willow Coyote-Maestas, James S Fraser
doaj   +1 more source

Viro-antibody therapy: engineering oncolytic viruses for genetic delivery of diverse antibody-based biotherapeutics

mAbs, 2021
Cancer therapeutics approved for clinical application include oncolytic viruses and antibodies, which evolved by nature, but were improved by molecular engineering.
Roland E. Kontermann, Guy Ungerechts, Dirk M. Nettelbeck   +2 more
doaj   +1 more source

Attenuating RNA Viruses with Expanded Genetic Codes to Evoke Adjustable Immune Response in PylRS-${\mathbf{tRNA}}_{\mathbf{CUA}}^{\mathbf{Pyl}}$ Transgenic Mice

Vaccines, 2023
Ribonucleic acid (RNA) viruses pose heavy burdens on public-health systems. Synthetic biology holds great potential for artificially controlling their replication, a strategy that could be used to attenuate infectious viruses but is still in the ...
Zhetao Zheng, Xuesheng Wu, Yu Wang, Xu Yang, Hongmin Chen, Yuxuan Shen, Yuelin Yang, Qing Xia   +7 more
doaj   +1 more source

The virus as metabolic engineer [PDF]

Biotechnology Journal, 2010
AbstractRecent genome‐wide screens of host genetic requirements for viral infection have reemphasized the critical role of host metabolism in enabling the production of viral particles. In this review, we highlight the metabolic aspects of viral infection found in these studies, and focus on the opportunities these requirements present for metabolic ...
Nathaniel D, Maynard, Miriam V, Gutschow, Elsa W, Birch, Markus W, Covert   +3 more
openaire   +2 more sources

Unreachable Peers Communication Scheme in Decentralized Networks Based on Peer-to-Peer Overlay Approaches

Future Internet, 2022
Decentralized networks bring us many benefits, but as networks evolve, many nodes either actively or passively become unreachable behind an NAT or a firewall.
Gengxian Li, Chundong Wang, Huaibin Wang
doaj   +1 more source

Reduced binding activity of vaccine serum to omicron receptor-binding domain

Frontiers in Immunology, 2022
Coronavirus disease 2019 (COVID-19) vaccination regimens contribute to limiting the spread of severe acute respiratory syndrome Coronavirus-2 (SARS-CoV-2).
Mingzhi Li, Shiqi Weng, Quansheng Wang, Zibing Yang, Xiaoling Wang, Xiaoling Wang, Yanjun Yin, Qiuxiang Zhou, Lirong Zhang, Feifei Tao, Yihan Li, Mengle Jia, Lingdi Yang, Xiu Xin, Hanguang Li, Lumei Kang, Lumei Kang, Yu Wang, Ting Wang, Sha Li, Lingbao Kong   +20 more
doaj   +1 more source

Reverse Genetics Systems for Emerging and Re-Emerging Swine Coronaviruses and Applications

Viruses, 2023
Emerging and re-emerging swine coronaviruses (CoVs), including porcine epidemic diarrhea virus (PEDV), porcine deltacoronavirus (PDCoV), and swine acute diarrhea syndrome-CoV (SADS-CoV), cause severe diarrhea in neonatal piglets, and CoV infection is ...
Hui Jiang, Ting Wang, Lingbao Kong, Bin Li, Qi Peng   +4 more
doaj   +1 more source

Japanese Encephalitis Virus: An Update on the Potential Antivirals and Vaccines

Vaccines, 2023
Japanese encephalitis virus (JEV) is the causal agent behind Japanese encephalitis (JE), a potentially severe brain infection that spreads through mosquito bites.
Kumar Saurabh Srivastava, Vandana Jeswani, Nabanita Pal, Babita Bohra, Vaishali Vishwakarma, Atharva Ashish Bapat, Yamini Prashanti Patnaik, Navin Khanna, Rahul Shukla   +8 more
doaj   +1 more source

String Searching Engine for Virus Scanning [PDF]

IEEE Transactions on Computers, 2011
A memory-efficient hardware string searching engine for antivirus applications is presented. The proposed QSV method is based on quick sampling of the input stream against fixed-length pattern prefixes, and on-demand verification of variable-length pattern suffixes.
Derek Chi-Wai Pao, Xing Wang, Xiaoran Wang, Cong Cao, Yuesheng Zhu   +4 more
openaire   +1 more source

Virosome: An engineered virus for vaccine delivery

Saudi Pharmaceutical Journal, 2023
The purpose of immunization is the effective cellular and humoral immune response against antigens. Several studies on novel vaccine delivery approaches such as micro-particles, liposomes & nanoparticles, etc. against infectious diseases have been investigated so far.
Hasan Ali, Md. Akbar, Babar Iqbal, Faraat Ali, Neeraj Kant Sharma, Nitin Kumar, Asim Najmi, Mohammed Albratty, Hassan A. Alhazmi, Osama A. Madkhali, Khalid Zoghebi, Md Shamsher Alam   +11 more
openaire   +3 more sources