Results 21 to 30 of about 218,144 (258)
Frontiers in Veterinary Science, 2022 Foot-and-mouth disease virus (FMDV) is an acute, highly contagious, and economically destructive pathogen of vesicular disease that affects domestic and wild cloven-hoofed animals. The FMDV VP1 protein is an important part of the nucleocapsid and plays a
Li Yang +24 more
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Oncolytic Adenovirus—A Nova for Gene-Targeted Oncolytic Viral Therapy in HCC
Frontiers in Oncology, 2019 Hepatocellular carcinoma (HCC) is one of the most frequent cancers worldwide, particularly in China. Despite the development of HCC treatment strategies, the survival rate remains unpleasant.
Mubalake Abudoureyimu +5 more
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Establishment of RT-RPA-Cas12a assay for rapid and sensitive detection of human rhinovirus B
BMC Microbiology, 2023 Human rhinovirus B (HRV-B) is a major human viral pathogen that can be responsible for various kinds of infections. Due to the health risks associated with HRV-B, it is therefore crucial to explore a rapid, specific, and sensitive method for surveillance.
Yongdong Li +5 more
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A recombinase polymerase amplification–based assay for rapid detection of Chlamydia psittaci
Poultry Science, 2021 Chlamydia psittaci is a zoonotic agent of systemic wasting disease in birds and atypical pneumonia in mammalians including humans, constituting a public health risk. A rapid diagnostic assay would be beneficial in screening C. psittaci in the field.
Yanling Pang +6 more
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RNA-Based Technologies for Engineering Plant Virus Resistance
Plants, 2021 In recent years, non-coding RNAs (ncRNAs) have gained unprecedented attention as new and crucial players in the regulation of numerous cellular processes and disease responses. In this review, we describe how diverse ncRNAs, including both small RNAs and
Michael Taliansky +5 more
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Virus engineering: functionalization and stabilization [PDF]
Protein Engineering Design and Selection, 2010 Chemically and/or genetically engineered viruses, viral capsids and viral-like particles carry the promise of important and diverse applications in biomedicine, biotechnology and nanotechnology. Potential uses include new vaccines, vectors for gene therapy and targeted drug delivery, contrast agents for molecular imaging and building blocks for the ...
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Vaccines, 2020 The miRNA-based strategy has been used to develop live attenuated influenza vaccines. In this study, the nucleoprotein (NP) genome segment of the influenza virus was inserted by different perfect miRNA-192-5p target sites, and the virus was rescued by ...
Feixia Gao +8 more
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Nature Communications, 2021 Current HCV nucleic acid-based diagnosis is largely performed in centralised laboratories. Here, the authors present a pan-genotypic RNA assay, based on reverse transcriptase loop mediated isothermal amplification and develop a low-cost prototype paper ...
Weronika Witkowska McConnell +11 more
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Pathogenicity and molecular characterization of infectious bursal disease virus in China
Poultry Science, 2022 : Infectious bursal disease virus (IBDV) caused an acute and highly contagious infectious disease, resulting in considerable economic losses in the world poultry industry.
Jiamin Lian +9 more
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Engineering resistance to virus transmission
Current Opinion in Virology, 2017 Engineering plants for resistance to virus transmission by invertebrate vectors has lagged behind other forms of plant protection. Vectors typically transmit more than one virus. Thus, vector resistance could provide a wider range of protection than defenses directed solely against one virus or virus group.
Carr, JP +3 more
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