Results 1 to 10 of about 594,928 (357)

A large population sample of African HIV genomes from the 1980s reveals a reduction in subtype D over time associated with propensity for CXCR4 tropism

Retrovirology, 2022
We present 109 near full-length HIV genomes amplified from blood serum samples obtained during early 1986 from across Uganda, which to our knowledge is the earliest and largest population sample from the initial phase of the HIV epidemic in Africa ...
Heather E. Grant, Sunando Roy, Rachel Williams, Helena Tutill, Bridget Ferns, Patricia A. Cane, J. Wilson Carswell, Deogratius Ssemwanga, Pontiano Kaleebu, Judith Breuer, Andrew J. Leigh Brown   +10 more
doaj   +1 more source

SARS-CoV-2 variants: Impact on biological and clinical outcome

Frontiers in Medicine, 2022
The severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) that was first identified in December 2019, in Wuhan, China was found to be the etiological agent for a novel respiratory infection that led to a Coronavirus Induced Disease named COVID-19.
Shakuntala Mahilkar, Sachee Agrawal, Sakshi Chaudhary, Swapneil Parikh, Subash C. Sonkar, Subash C. Sonkar, Dileep Kumar Verma, Vidushi Chitalia, Divya Mehta, Bidhan Chandra Koner, Bidhan Chandra Koner, Neetu Vijay, Jayanthi Shastri, Sujatha Sunil   +13 more
doaj   +1 more source

Frequent horizontal and mother-to-child transmission may contribute to high prevalence of STLV-1 infection in Japanese macaques

Retrovirology, 2020
Background Simian T-cell leukemia virus type 1 (STLV-1) is disseminated among various non-human primate species and is closely related to human T-cell leukemia virus type 1 (HTLV-1), the causative agent of adult T-cell leukemia and HTLV-1-associated ...
Megumi Murata, Jun-ichirou Yasunaga, Ayaka Washizaki, Yohei Seki, Madoka Kuramitsu, Wei Keat Tan, Anna Hu, Kazu Okuma, Isao Hamaguchi, Takuo Mizukami, Masao Matsuoka, Hirofumi Akari   +11 more
doaj   +1 more source

Molecular epidemiology and pathogenicity of H5N1 and H9N2 avian influenza viruses in clinically affected chickens on farms in Bangladesh

Emerging Microbes and Infections, 2021
Avian influenza virus (AIV) subtypes H5N1 and H9N2 co-circulate in poultry in Bangladesh, causing significant bird morbidity and mortality. Despite their importance to the poultry value chain, the role of farms in spreading and maintaining AIV infections
Ripatun Nahar Ripa, Joshua E. Sealy, Jayna Raghwani, Tridip Das, Himel Barua, Md. Masuduzzaman, A. K. M. Saifuddin, Md. Reajul Huq, Mohammad Inkeyas Uddin, Munir Iqbal, Ian Brown, Nicola S. Lewis, Dirk Pfeiffer, Guillaume Fournie, Paritosh Kumar Biswas   +14 more
doaj   +1 more source

Immunoinformatic Analysis Reveals Antigenic Heterogeneity of Epstein-Barr Virus Is Immune-Driven

Frontiers in Immunology, 2021
Whole genome sequencing of Epstein-Barr virus (EBV) isolates from around the world has uncovered pervasive strain heterogeneity, but the forces driving strain diversification and the impact on immune recognition remained largely unknown.
Ana Cirac, Ana Cirac, Remy Poirey, Michael Dieckmeyer, Klaus Witter, Henri-Jacques Delecluse, Uta Behrends, Uta Behrends, Uta Behrends, Josef Mautner, Josef Mautner, Josef Mautner   +11 more
doaj   +1 more source

Natural Populations from the Phytophthora palustris Complex Show a High Diversity and Abundance of ssRNA and dsRNA Viruses

Journal of Fungi, 2022
We explored the virome of the “Phytophthora palustris complex”, a group of aquatic specialists geographically limited to Southeast and East Asia, the native origin of many destructive invasive forest Phytophthora spp. Based on high-throughput sequencing (
Leticia Botella, Marília Horta Jung, Michael Rost, Thomas Jung   +3 more
doaj   +1 more source

Is HIV short-sighted? Insights from a multistrain nested model [PDF]

, 2013
An important component of pathogen evolution at the population level is evolution within hosts. Unless evolution within hosts is very slow compared to the duration of infection, the composition of pathogen genotypes within a host is likely to change ...
Fraser, Christophe, Lythgoe, Katrina A., Pellis, Lorenzo   +2 more
core   +3 more sources

Participation of Multifunctional RNA in Replication, Recombination and Regulation of Endogenous Plant Pararetroviruses (EPRVs)

Frontiers in Plant Science, 2021
Pararetroviruses, taxon Caulimoviridae, are typical of retroelements with reverse transcriptase and share a common origin with retroviruses and LTR retrotransposons, presumably dating back 1.6 billion years and illustrating the transition from an RNA to ...
Katja R. Richert-Pöggeler, Kitty Vijverberg, Kitty Vijverberg, Osamah Alisawi, Gilbert N. Chofong, J. S. (Pat) Heslop-Harrison, J. S. (Pat) Heslop-Harrison, Trude Schwarzacher, Trude Schwarzacher   +8 more
doaj   +1 more source

Nucleotide bias of DCL and AGO in plant anti-virus gene silencing [PDF]

, 2010
Plant Dicer-like (DCL) and Argonaute (AGO) are the key enzymes involved in anti-virus post-transcriptional gene silencing (AV-PTGS). Here we show that AV-PTGS exhibited nucleotide preference by calculating a relative AV-PTGS efficiency on processing ...
Dalmay, Tamas, Ho, Thien, Huang, Linfeng, Li, Zhigang, Ohshima, Kazusato, Pallett, Denise W., Walsh, John A., Wang, Hui, Wang, Liang   +8 more
core   +1 more source

Variability in P1 gene redefines phylogenetic relationships among cassava brown streak viruses

Virology Journal, 2017
Background Cassava brown streak disease is emerging as the most important viral disease of cassava in Africa, and is consequently a threat to food security.
Willard Mbewe, Fred Tairo, Peter Sseruwagi, Joseph Ndunguru, Siobain Duffy, Ssetumba Mukasa, Ibrahim Benesi, Samar Sheat, Marianne Koerbler, Stephan Winter   +9 more
doaj   +1 more source