Results 141 to 150 of about 241,522 (268)

Race with virus evolution: The development and application of mRNA vaccines against SARS-CoV-2. [PDF]

Biomed J, 2023
Lee KM, Lin SJ, Wu CJ, Kuo RL.
europepmc   +1 more source

Onasemnogene Abeparvovec in Type I Spinal Muscular Atrophy: 24‐Month Follow‐Up From the Italian Registry

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Onasemnogene abeparvovec (OA) is an AAV9‐based gene therapy for spinal muscular atrophy type I (SMA I). Real‐world outcomes show increased response variability compared to clinical trials, and follow‐up data beyond 12–18 months are limited.
Marika Pane, Giorgia Coratti, Chiara Cutrì, Antonio Varone, Riccardo Masson, Adele D'Amico, Valeria Sansone, Sonia Messina, Federica Ricci, Chiara Ticci, Claudio Bruno, Caterina Agosto, Francesca Benedetti, Antonella Pini, Sabrina Siliquini, Massimiliano Filosto, Alberto Zambon, Ilaria Bitetti, Maria Rosaria Manna, Claudia Dosi, Riccardo Zanin, Stefano Parravicini, Roberto De Sanctis, Giulia Stanca, Michela Catteruccia, Michele Tosi, Irene Mizzoni, Emilio Albamonte, Valentina Franchino, Maria Sframeli, Ilaria Cavallina, Elena Procopio, Michele Sacchini, Simone Morando, Noemi Brolatti, Federica Trucco, Gaia Scarpini, Elena Briganti, Beatrice Berti, Concetta Palermo, Daniela Leone, Stefano C. Previtali, Eugenio Mercuri, the ITASMAC working group   +43 more
wiley   +1 more source

Analysis of temporal virus evolution and intra-host diversity in long-term non-progressors by bulk next-generation sequencing. [PDF]

Microbiol Spectr
Chen R, Mo J, Li Y, Wu Y, Chen F, Qin Q, Yang H, Xie C, Li K, Huang Y, Wei W, Yuan Z, Ye L, Liang H, Jiang J.   +14 more
europepmc   +1 more source

Molecular evolution of influenza A virus.

Uirusu, 1986
Nakajima, Katsuhisa, Nobusawa, Eri, Nakajima, Setsuko   +2 more
openaire   +3 more sources

ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan, Yan Jiang, Yuxuan Yong, Tianshuo Zhang, Niannian Zhang, Qianqian Zeng, Xue Gong, Li Meng, Fangfang Bi, Yongmin Liu   +9 more
wiley   +1 more source

Matryoshka Dolls of Virus Evolution: The Internal Forces That Shape Viral Fate. [PDF]

Integr Comp Biol
Yin J.
europepmc   +1 more source

Cryo-EM structure of ssDNA bacteriophage ΦCjT23 provides insight into early virus evolution. [PDF]

Nat Commun, 2022
Kejzar N, Laanto E, Rissanen I, Abrishami V, Selvaraj M, Moineau S, Ravantti J, Sundberg LR, Huiskonen JT.   +8 more
europepmc   +1 more source

Influenza Vaccination Responses in Disabled Stroke Patients: A Single‐Center Prospective Observational Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study aimed to investigate the immunological response to influenza vaccination, the incidence and severity of influenza infection, and the side effects of the vaccination in patients with ischemic stroke. Methods This prospective observational study was conducted between 2023 and 2024 at Ramathibodi Hospital.
Achiraya Pakngao, Sureerat Suwatcharangoon, Pintip Ngamjanyapron, Kobporn Boonnak, Thanitta Suangtamai, Porpon Rotjanapan   +5 more
wiley   +1 more source

"Fertile" Mutations in SARS-CoV-2 RNA More Frequently Occurred in Hairpin Loops That Determine Virus Evolution. [PDF]

APMIS
Colson P, Pontarotti P, Fantini J, Levasseur A, Devaux C, Raoult D.   +5 more
europepmc   +1 more source

Introduction of a PRRSV-1 strain of increased virulence in a pig production structure in Spain: virus evolution and impact on production. [PDF]

Porcine Health Manag, 2023
Martín-Valls GE, Cortey M, Allepuz A, Illas F, Tello M, Mateu E.   +5 more
europepmc   +1 more source