Results 11 to 20 of about 610,244 (306)

Virus evolution affected early COVID-19 spread [PDF]

, 2020
Corcoran D, Urban MC, Wegrzyn J, Merow C.   +3 more
europepmc   +2 more sources

Is HIV short-sighted? Insights from a multistrain nested model [PDF]

, 2013
An important component of pathogen evolution at the population level is evolution within hosts. Unless evolution within hosts is very slow compared to the duration of infection, the composition of pathogen genotypes within a host is likely to change ...
Fraser, Christophe, Lythgoe, Katrina A., Pellis, Lorenzo   +2 more
core   +3 more sources

Dating the Emergence of Human Endemic Coronaviruses

Viruses, 2022
Four endemic coronaviruses infect humans and cause mild symptoms. Because previous analyses were based on a limited number of sequences and did not control for effects that affect molecular dating, we re-assessed the timing of endemic coronavirus ...
Diego Forni, Rachele Cagliani, Uberto Pozzoli, Alessandra Mozzi, Federica Arrigoni, Luca De Gioia, Mario Clerici, Manuela Sironi   +7 more
doaj   +1 more source

Canalization of the evolutionary trajectory of the human influenza virus [PDF]

, 2011
Since its emergence in 1968, influenza A (H3N2) has evolved extensively in genotype and antigenic phenotype. Antigenic evolution occurs in the context of a two-dimensional 'antigenic map', while genetic evolution shows a characteristic ladder-like ...
A Kucharski, A Monto, A Park, A Rambaut, Andrew Rambaut, B Adams, B Finkelman, C Viboud, CA Russell, D Weinreich, DJ Smith, E Goldstein, E O'Dea, E Volz, F Carrat, F Tria, G Chowell, G Hirst, IG Barr, J Gog, J Lin, J O'Brien, J Truscott, J Voeten, K Koelle, K Koelle, K Koelle, K Koelle, M Recker, Mercedes Pascual, MI Nelson, NM Ferguson, R Bush, S Bhatt, S Gould, S Kryazhimskiy, S Park, T Bedford, T Bedford, Trevor Bedford, V Gupta, WM Fitch, YI Wolf, Z Yang   +43 more
core   +5 more sources

Variability in P1 gene redefines phylogenetic relationships among cassava brown streak viruses

Virology Journal, 2017
Background Cassava brown streak disease is emerging as the most important viral disease of cassava in Africa, and is consequently a threat to food security.
Willard Mbewe, Fred Tairo, Peter Sseruwagi, Joseph Ndunguru, Siobain Duffy, Ssetumba Mukasa, Ibrahim Benesi, Samar Sheat, Marianne Koerbler, Stephan Winter   +9 more
doaj   +1 more source

Recombination and Positive Selection Differentially Shaped the Diversity of Betacoronavirus Subgenera

Viruses, 2020
The Betacoronavirus genus of mammal-infecting viruses includes three subgenera (Sarbecovirus, Embecovirus, and Merbecovirus), in which most known human coronaviruses, including SARS-CoV-2, cluster.
Diego Forni, Rachele Cagliani, Manuela Sironi   +2 more
doaj   +1 more source

Nucleotide bias of DCL and AGO in plant anti-virus gene silencing [PDF]

, 2010
Plant Dicer-like (DCL) and Argonaute (AGO) are the key enzymes involved in anti-virus post-transcriptional gene silencing (AV-PTGS). Here we show that AV-PTGS exhibited nucleotide preference by calculating a relative AV-PTGS efficiency on processing ...
Dalmay, Tamas, Ho, Thien, Huang, Linfeng, Li, Zhigang, Ohshima, Kazusato, Pallett, Denise W., Walsh, John A., Wang, Hui, Wang, Liang   +8 more
core   +1 more source

Unveiling Crucivirus Diversity by Mining Metagenomic Data

mBio, 2020
The discovery of cruciviruses revealed the most explicit example of a common protein homologue between DNA and RNA viruses to date. Cruciviruses are a novel group of circular Rep-encoding single-stranded DNA (ssDNA) (CRESS-DNA) viruses that encode capsid
Ignacio de la Higuera, George W. Kasun, Ellis L. Torrance, Alyssa A. Pratt, Amberlee Maluenda, Jonathan Colombet, Maxime Bisseux, Viviane Ravet, Anisha Dayaram, Daisy Stainton, Simona Kraberger, Peyman Zawar-Reza, Sharyn Goldstien, James V. Briskie, Robyn White, Helen Taylor, Christopher Gomez, David G. Ainley, Jon S. Harding, Rafaela S. Fontenele, Joshua Schreck, Simone G. Ribeiro, Stephen A. Oswald, Jennifer M. Arnold, François Enault, Arvind Varsani, Kenneth M. Stedman   +26 more
doaj   +1 more source

Immunoinformatic Analysis Reveals Antigenic Heterogeneity of Epstein-Barr Virus Is Immune-Driven

Frontiers in Immunology, 2021
Whole genome sequencing of Epstein-Barr virus (EBV) isolates from around the world has uncovered pervasive strain heterogeneity, but the forces driving strain diversification and the impact on immune recognition remained largely unknown.
Ana Cirac, Ana Cirac, Remy Poirey, Michael Dieckmeyer, Klaus Witter, Henri-Jacques Delecluse, Uta Behrends, Uta Behrends, Uta Behrends, Josef Mautner, Josef Mautner, Josef Mautner   +11 more
doaj   +1 more source

Virus satellites drive viral evolution and ecology [PDF]

, 2015
Virus satellites are widespread subcellular entities, present both in eukaryotic and in prokaryotic cells. Their modus vivendi involves parasitism of the life cycle of their inducing helper viruses, which assures their transmission to a new host. However,
Buckling, Angus, Donderis, Jorge, Elena, Santiago F., Frígols, Belén, Marina, Alberto, Mir-Sanchis, Ignacio, Novick, Richard P., Penades, Jose R., Quiles-Puchalt, Nuria   +8 more
core   +1 more source