Defects in plant immunity modulate the rates and patterns of RNA virus evolution [PDF]
Virus Evol, 2022 It is assumed that host genetic variability for susceptibility to infection necessarily conditions virus evolution. Differences in host susceptibility can either drive the virus to diversify into strains that track different defense alleles (e.g ...
Rebeca Navarro +7 more
semanticscholar +3 more sources
Host Membranes as Drivers of Virus Evolution [PDF]
Viruses, 2023 The molecular mechanisms controlling the adaptation of viruses to host cells are generally poorly documented. An essential issue to resolve is whether host membranes, and especially lipid rafts, which are usually considered passive gateways for many ...
Mélanie Matveeva +4 more
semanticscholar +2 more sources
High-resolution mapping reveals the mechanism and contribution of genome insertions and deletions to RNA virus evolution [PDF]
Proc Natl Acad Sci U S A, 2023 Significance RNA viruses are masters at rapid adaptation to adverse conditions. One important and poorly understood viral adaptation strategy is the use of genome insertions and deletions (indels) as a source of variation and evolutionary novelty.
Mauricio Aguilar Rangel +5 more
semanticscholar +2 more sources
Cell Host & Microbe, 2022 Viruses are obligate intracellular parasites. Despite their dependence on host cells, viruses are evolutionarily autonomous, with their own genomes and evolutionary trajectories locked in arms races with the hosts. Here, we discuss a simple functional logic to explain virus macroevolution that appears to define the course of virus evolution.
E. Koonin, V. Dolja, M. Krupovic
semanticscholar +4 more sources
High pathogenic avian influenza A(H5) viruses of clade 2.3.4.4b in Europe—Why trends of virus evolution are more difficult to predict [PDF]
Virus EvolSince 2016, A(H5Nx) high pathogenic avian influenza (HPAI) virus of clade 2.3.4.4b has become one of the most serious global threats not only to wild and domestic birds, but also to public health.
A. Fusaro +57 more
semanticscholar +2 more sources
Clinically Relevant Influenza Virus Evolution Reconstituted in a Human Lung Airway-on-a-Chip [PDF]
Microbiol Spectr, 2021 The rapid evolution of viruses, such as influenza viruses and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is challenging the use and development of antivirals and vaccines.
L. Si +5 more
semanticscholar +2 more sources
The Baltimore Classification of Viruses 50 Years Later: How Does It Stand in the Light of Virus Evolution? [PDF]
Microbiol Mol Biol Rev, 2021 Fifty years ago, David Baltimore published a brief conceptual paper delineating the classification of viruses by the routes of genome expression. The six “Baltimore classes” of viruses, with a subsequently added 7th class, became the conceptual framework
E. Koonin, M. Krupovic, V. Agol
semanticscholar +2 more sources
Inference of Nipah virus evolution, 1999-2015. [PDF]
Virus Evol, 2020 Despite near-annual human outbreaks of Nipah virus (NiV) disease in Bangladesh, typically due to individual spillover events from the local bat population, only twenty whole-genome NiV sequences exist from humans and ten from bats.
S. Whitmer +15 more
semanticscholar +2 more sources
The 2019‐new coronavirus epidemic: Evidence for virus evolution [PDF]
J Med Virol, 2020 There is concern about a new coronavirus, the 2019-nCoV, as a global public health threat. In this article, we provide a preliminary evolutionary and molecular epidemiological analysis of this new virus.
D. Benvenuto +5 more
semanticscholar +2 more sources
Infectious Bronchitis Virus Evolution, Diagnosis and Control [PDF]
Vet Sci, 2020 RNA viruses are characterized by high mutation and recombination rates, which allow a rapid adaptation to new environments. Most of the emerging diseases and host jumps are therefore sustained by these viruses.
M. Legnardi +3 more
semanticscholar +2 more sources