Results 71 to 80 of about 143,789 (304)

Inactivation of the enveloped virus phi6 with hydrodynamic cavitation

Ultrasonics Sonochemistry, 2023
The COVID −19 pandemic reminded us that we need better contingency plans to prevent the spread of infectious agents and the occurrence of epidemics or pandemics.
Mojca Zupanc, Jure Zevnik, Arijana Filipić, Ion Gutierrez-Aguirre, Meta Ješelnik, Tamara Košir, Jernej Ortar, Matevž Dular, Martin Petkovšek   +8 more
doaj   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Determination of the optimal inactivation time of FMD virus Type "A" using BEI inactivator during the outbreak 2006 in Egypt and its effect on the antigenicity of the virus

Journal of Veterinary Medical Research, 2018
FMD virus type A/1/ Egypt 2006 was inactivated with 0.1 M of BEI (Binary ethylene imine) formed by cyclization of 2- Bromoethyl-amine hydrobromide (BEA) in 0.2 N NaoH at 37oC with PH 8.0 for 24 hours.
A. A. Omar, H. M. A. Azab, M. M. Abdel-Aty, S. M. Ali, M. A. Farag   +4 more
doaj  

Inactivation of Pepper Mild Mottle Virus in Water by Cold Atmospheric Plasma

Frontiers in Microbiology, 2021
Water scarcity is one of the greatest threats for human survival and quality of life, and this is increasingly contributing to the risk of human, animal and plant infections due to waterborne viruses. Viruses are transmitted through polluted water, where
Arijana Filipić, Arijana Filipić, David Dobnik, Magda Tušek Žnidarič, Bojana Žegura, Alja Štern, Gregor Primc, Miran Mozetič, Maja Ravnikar, Maja Ravnikar, Jana Žel, Ion Gutierrez Aguirre   +11 more
doaj   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Does limited virucidal activity of biocides include duck hepatitis B virucidal action? [PDF]

, 2012
BACKGROUND: There is agreement that the infectivity assay with the duck hepatitis B virus (DHBV) is a suitable surrogate test to validate disinfectants for hepatitis B virucidal activity.
Wutzler, Peter, Bust, Uwe, Peter Wutzler, Michael Schacke, Uwe Bust, Rabenau, Holger, Brigitte Glück, Holger F Rabenau, Glück, Brigitte, Andreas Sauerbrei, Sauerbrei, Andreas, Schacke, Michael   +11 more
core   +1 more source

Study on the relationship between viral inactivation and alkyl chain length of benzalkonium chloride.

PLoS ONE
Alkyldimethylbenzylammonium chloride (BAC), a quaternary ammonium salt surfactant, is commonly utilized as a sanitizer and disinfectant. Concerns have emerged regarding the increasing global exposure to BAC, emphasizing the need for strategies to ...
Ikumi Takada, Atsushi Miyazaki, Chisato Igarashi, Yukiko Yamawaki, Atsuko Hayase, Takuya Mori, Takaya Sakai   +6 more
doaj   +1 more source

Disinfection of Ebola Virus in Sterilized Municipal Wastewater.

PLoS Neglected Tropical Diseases, 2017
Concerns have been raised regarding handling of Ebola virus contaminated wastewater, as well as the adequacy of proposed disinfection approaches. In the current study, we investigate the inactivation of Ebola virus in sterilized domestic wastewater ...
Kyle Bibby, Robert J Fischer, Leonard W Casson, Nathalia Aquino de Carvalho, Charles N Haas, Vincent J Munster   +5 more
doaj   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

The effect of interferon on the transcription pattern of parainfluenza virus 5 [PDF]

, 2013
Interferon (IFN) is activated in response to virus infections and upregulates interferon-stimulated genes (ISGs) resulting in the expression of hundreds of proteins, many of which have direct or indirect antiviral activity.
Norsted, Hanna
core