National Seroprevalence and Risk Factors of Bluetongue Virus in Domestic Ruminants of Peru
Bluetongue (BT) is a viral infection caused by the bluetongue virus (BTV) that affects domestic and wild ruminants worldwide. It is primarily transmitted by Culicoides spp. midges, and its infection is highly prevalent across temperate and tropical regions.
Dennis A. Navarro-Mamani +13 more
wiley +1 more source
A single mutation (V64G) within the RING Domain of Z attenuates Junin virus.
Junin virus (JUNV) is a New World arenavirus that is the causative agent of Argentine hemorrhagic fever (AHF). Candid#1 (Can) is a live-attenuated vaccine strain of JUNV that since its introduction has resulted in a marked decrease in AHF incidence ...
Steven J Hallam +7 more
doaj +1 more source
Junin virus‐induced astrocytosis is impaired by iNOS inhibition
AbstractBecause Junin virus (JV) experimental encephalitis of mice and rats is characterized by mild histopathological changes that do not seem to justify per se lethality after intracerebral infection, such a murine model seems adequate to investigate the potential role of inducible nitric oxide synthase (iNOS) as a pathogenic factor. Concomitant with
Gomez, Ricardo Martin +3 more
openaire +3 more sources
Andean Lima Bean Ecology and Its Potential Contribution to Food Security
ABSTRACT The Andean lima bean (ALB) (Phaseolus lunatus L.), also known as “Pallar” in Peru, is a large, semi‐flat, kidney‐shaped rarely investigated legume. This ancestral legume lacks in‐depth scientific reports and is mainly cultivated in the coastal region of the Ica valley. Its consumption dates back to ancient times, as evidenced by archaeological
Isabel Milagros Gavilan‐Figari +4 more
wiley +1 more source
Analysis of the Cell Type-Dependence on the Arenavirus Z-Mediated Virus-Like Particle Production
Several arenaviruses are highly pathogenic to humans, causing hemorrhagic fever. Discovery of anti-arenavirus drug candidates is urgently needed, although the molecular basis of the host- and organ-specific pathogenicity remains to be fully elucidated ...
Patrick I. Mpingabo +6 more
doaj +1 more source
Prevalence and Incidence of Parkinson's Disease in Latin America: A Meta‐Analysis
Abstract Background Parkinson's disease (PD) is a rapidly growing neurodegenerative disorder, but up‐to‐date epidemiological data are lacking in Latin America. We sought to estimate the prevalence and incidence of PD and parkinsonism in Latin America. Methods We searched Medline, Embase, Scopus, Web of Science, Scientific Electronic Library Online, and
Dani J. Kim +9 more
wiley +1 more source
Antimicrobial peptides for novel antiviral strategies in the current post‐COVID‐19 pandemic
This review describes the main physicochemical characteristics of antimicrobial peptides, with particular focus on peptides derived from amphibian skin. Summarizing the various antiviral activities of these peptides and the underlying mechanism, this review emphasizes the high potential of these small molecules for the development of new antiviral ...
Maria Rosa Loffredo +3 more
wiley +1 more source
Host Cell Factors as Antiviral Targets in Arenavirus Infection
Among the members of the Arenaviridae family, Lassa virus and Junin virus generate periodic annual outbreaks of severe human hemorrhagic fever (HF) in endemic areas of West Africa and Argentina, respectively.
Elsa B. Damonte +6 more
doaj +1 more source
A One Health approach for South American hemorrhagic fevers
South American hemorrhagic fevers (SAHF) include five rodent-borne New World mammarenaviruses. These are Junin, Machupo, Chapare, Guanarito, and Sabia viruses.
Dr Rory Wilson, Dr Ariella Barry
doaj +1 more source
Type I interferon underlies severe disease associated with Junín virus infection in mice
Junín virus (JUNV) is one of five New World mammarenaviruses (NWMs) that causes fatal hemorrhagic disease in humans and is the etiological agent of Argentine hemorrhagic fever (AHF).
Brady T Hickerson +5 more
doaj +1 more source

