Results 51 to 60 of about 3,174 (230)

Application of multiplex realtime PCR detection for hemorrhagic fever syndrome viruses

open access: yesJournal of Infection and Public Health, 2023
Background: Multiplex real-time PCR is a quick and cost effective method for detection of various gene simultaneously. HFSV (Hemorrhagic Fever Syndrome Virus) is a newly emerging infectious disease because of globalization and climate change. We tried to
Yoonhyuk Choi, Younghee Kim
doaj   +1 more source

EXPERIENCE OF STUDY AND POSSIBLE WAYS OF ELIMINATION OF FALSE POSITIVE AND FALSE NEGATIVE RESULTS DURING EXECUTION OF POLYMERASE CHAIN REACTION ON AN EXAMPLE OF JUNIN VIRUS RNA DETECTION

open access: yesЖурнал микробиологии, эпидемиологии и иммунобиологии, 2015
Aim. Experience of study and possible ways of elimination of false positive and false negative results during execution of polymerase chain reaction on an example of Junin virus RNA detection. Materials and methods.
T. E Sizikova   +4 more
doaj  

Junin Virus Triggers Macrophage Activation and Modulates Polarization According to Viral Strain Pathogenicity

open access: yesFrontiers in Immunology, 2019
The New World arenavirus Junin (JUNV) is the etiological agent of Argentine hemorrhagic fever (AHF). Previous studies of human macrophage infection by the Old-World arenaviruses Mopeia and Lassa showed that while the non-pathogenic Mopeia virus ...
María F. Ferrer   +12 more
doaj   +1 more source

Two Birds With One Stone: RNA Virus Strategies to Manipulate G3BP1 and Other Stress Granule Components

open access: yesWIREs RNA, Volume 16, Issue 2, March/April 2025.
Stress granules emerging during viral infection can play both pro‐ and antiviral roles. RNA viruses use various strategies to antagonize their formation, including the degradation, inhibition, or sequestration of G3BP1, a key stress granule protein. However, biochemical and structural insights into these mechanisms have been reported for only a handful
Moh Egy Rahman Firdaus   +3 more
wiley   +1 more source

Nipah Virus Infection Generates Ordered Structures in Cellulo

open access: yesViruses, 2022
Nipah virus (NiV) is a zoonotic paramyxovirus with a fatality rate of up to 92% in humans. While several pathogenic mechanisms used by NiV to counteract host immune defense responses have been described, all of the processes that take place in cells ...
Cecilia Alejandra Vázquez   +12 more
doaj   +1 more source

Biological Activities of Junin Virus Proteins

open access: yesIntervirology, 1980
In the Junin virus-infected cell, there is a soluble antigen (SAg), which we have detected by complement fixation.
Maria Ines de Mitri   +1 more
openaire   +1 more source

Exploring the druggability of the UEV domain of human TSG101 in search for broad‐spectrum antivirals

open access: yesProtein Science, Volume 34, Issue 1, January 2025.
Abstract The ubiquitin E2 variant domain of TSG101 (TSG101‐UEV) plays a pivotal role in protein sorting and virus budding by recognizing PTAP motifs within ubiquitinated proteins. Disruption of TSG101‐UEV/PTAP interactions has emerged as a promising strategy for the development of host‐oriented broad‐spectrum antivirals with low susceptibility to ...
Fernando Montero   +17 more
wiley   +1 more source

Phytochemical Analysis and Pharmaceutical Applications of Monoterpenoids Present in the Essential Oil of Boswellia sacra (Omani Luban)

open access: yesAdvances in Pharmacological and Pharmaceutical Sciences, Volume 2025, Issue 1, 2025.
Due to its intricacy and long‐term usefulness, traditional medicine continues to be practiced in several nations. Among the many medicinal plants found in the Dhofar region of Oman, the aromatic oleo‐gum resin generated by Boswellia sacra, commonly referred to as frankincense, stands out for its medical and commercial significance. Resin‐carrying ducts
Foziya Khan, Luay Rashan, Kuldeep Singh
wiley   +1 more source

National Seroprevalence and Risk Factors of Bluetongue Virus in Domestic Ruminants of Peru

open access: yesTransboundary and Emerging Diseases, Volume 2025, Issue 1, 2025.
Bluetongue (BT) is a viral infection caused by the bluetongue virus (BTV) that affects domestic and wild ruminants worldwide. It is primarily transmitted by Culicoides spp. midges, and its infection is highly prevalent across temperate and tropical regions.
Dennis A. Navarro-Mamani   +13 more
wiley   +1 more source

Junin virus‐induced astrocytosis is impaired by iNOS inhibition

open access: yesJournal of Medical Virology, 2002
AbstractBecause Junin virus (JV) experimental encephalitis of mice and rats is characterized by mild histopathological changes that do not seem to justify per se lethality after intracerebral infection, such a murine model seems adequate to investigate the potential role of inducible nitric oxide synthase (iNOS) as a pathogenic factor. Concomitant with
Gomez, Ricardo Martin   +3 more
openaire   +3 more sources

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