Results 61 to 70 of about 3,174 (230)
A single mutation (V64G) within the RING Domain of Z attenuates Junin virus.
PLoS Neglected Tropical Diseases, 2020 Junin virus (JUNV) is a New World arenavirus that is the causative agent of Argentine hemorrhagic fever (AHF). Candid#1 (Can) is a live-attenuated vaccine strain of JUNV that since its introduction has resulted in a marked decrease in AHF incidence ...
Steven J Hallam +7 more
doaj +1 more source
Andean Lima Bean Ecology and Its Potential Contribution to Food Security
Legume Science, Volume 6, Issue 2, June 2024.ABSTRACT The Andean lima bean (ALB) (Phaseolus lunatus L.), also known as “Pallar” in Peru, is a large, semi‐flat, kidney‐shaped rarely investigated legume. This ancestral legume lacks in‐depth scientific reports and is mainly cultivated in the coastal region of the Ica valley. Its consumption dates back to ancient times, as evidenced by archaeological
Isabel Milagros Gavilan‐Figari +4 more
wiley +1 more source
Analysis of the Cell Type-Dependence on the Arenavirus Z-Mediated Virus-Like Particle Production
Frontiers in Microbiology, 2020 Several arenaviruses are highly pathogenic to humans, causing hemorrhagic fever. Discovery of anti-arenavirus drug candidates is urgently needed, although the molecular basis of the host- and organ-specific pathogenicity remains to be fully elucidated ...
Patrick I. Mpingabo +6 more
doaj +1 more source
Prevalence and Incidence of Parkinson's Disease in Latin America: A Meta‐Analysis
Movement Disorders, Volume 39, Issue 1, Page 105-118, January 2024.Abstract Background Parkinson's disease (PD) is a rapidly growing neurodegenerative disorder, but up‐to‐date epidemiological data are lacking in Latin America. We sought to estimate the prevalence and incidence of PD and parkinsonism in Latin America. Methods We searched Medline, Embase, Scopus, Web of Science, Scientific Electronic Library Online, and
Dani J. Kim +9 more
wiley +1 more source
Host Cell Factors as Antiviral Targets in Arenavirus Infection
Viruses, 2012 Among the members of the Arenaviridae family, Lassa virus and Junin virus generate periodic annual outbreaks of severe human hemorrhagic fever (HF) in endemic areas of West Africa and Argentina, respectively.
Elsa B. Damonte +6 more
doaj +1 more source
Involvement of the cytoskeleton in Junin virus multiplication.
Journal of General Virology, 1999 The role of the cellular cytoskeleton in Junin virus (JV) infection was explored in two ways. Firstly, the action of inhibitors that affect individual cytoskeletal systems (microtubules or microfilaments) selectively was analysed. It was found that perturbations of microtubule or microfilament networks caused by colchicine, nocodazole, nifedipine, EGTA
N A, Candurra +3 more
openaire +2 more sources
Antimicrobial peptides for novel antiviral strategies in the current post‐COVID‐19 pandemic
Journal of Peptide Science, Volume 30, Issue 1, January 2024.This review describes the main physicochemical characteristics of antimicrobial peptides, with particular focus on peptides derived from amphibian skin. Summarizing the various antiviral activities of these peptides and the underlying mechanism, this review emphasizes the high potential of these small molecules for the development of new antiviral ...
Maria Rosa Loffredo +3 more
wiley +1 more source
Comparative studies on Mopeia viruses and other Arenaviridae, particularly Lassa virus
, 1983 This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.Serologically related arenaviruses have been isolated from West Africa, Mozambique, Zimbabwe and the Central African Republic.
Lloyd, Graham
core
A One Health approach for South American hemorrhagic fevers
CABI One HealthSouth American hemorrhagic fevers (SAHF) include five rodent-borne New World mammarenaviruses. These are Junin, Machupo, Chapare, Guanarito, and Sabia viruses.
Dr Rory Wilson, Dr Ariella Barry
doaj +1 more source
Type I interferon underlies severe disease associated with Junín virus infection in mice
eLife, 2020 Junín virus (JUNV) is one of five New World mammarenaviruses (NWMs) that causes fatal hemorrhagic disease in humans and is the etiological agent of Argentine hemorrhagic fever (AHF).
Brady T Hickerson +5 more
doaj +1 more source