Results 61 to 70 of about 1,043,974 (224)

Andean Lima Bean Ecology and Its Potential Contribution to Food Security

Legume Science, Volume 6, Issue 2, June 2024.
ABSTRACT The Andean lima bean (ALB) (Phaseolus lunatus L.), also known as “Pallar” in Peru, is a large, semi‐flat, kidney‐shaped rarely investigated legume. This ancestral legume lacks in‐depth scientific reports and is mainly cultivated in the coastal region of the Ica valley. Its consumption dates back to ancient times, as evidenced by archaeological
Isabel Milagros Gavilan‐Figari, Marianela Inga, Indira Betalleluz‐Pallardel, Luz Marina Espinoza de Arenas, Raúl Comettant‐Rabanal   +4 more
wiley   +1 more source

A single mutation (V64G) within the RING Domain of Z attenuates Junin virus.

PLoS Neglected Tropical Diseases, 2020
Junin virus (JUNV) is a New World arenavirus that is the causative agent of Argentine hemorrhagic fever (AHF). Candid#1 (Can) is a live-attenuated vaccine strain of JUNV that since its introduction has resulted in a marked decrease in AHF incidence ...
Steven J Hallam, John T Manning, Junki Maruyama, Alexey Seregin, Cheng Huang, David H Walker, Juan Carlos de la Torre, Slobodan Paessler   +7 more
doaj   +1 more source

Prevalence and Incidence of Parkinson's Disease in Latin America: A Meta‐Analysis

Movement Disorders, Volume 39, Issue 1, Page 105-118, January 2024.
Abstract Background Parkinson's disease (PD) is a rapidly growing neurodegenerative disorder, but up‐to‐date epidemiological data are lacking in Latin America. We sought to estimate the prevalence and incidence of PD and parkinsonism in Latin America. Methods We searched Medline, Embase, Scopus, Web of Science, Scientific Electronic Library Online, and
Dani J. Kim, Ana L. Isidro‐Pérez, Michelle Doering, Juan J. Llibre‐Rodriguez, Isaac Acosta, Ana M. Rodriguez Salgado, Gabriel D. Pinilla‐Monsalve, Caroline Tanner, Jorge J. Llibre‐Guerra, Matthew Prina   +9 more
wiley   +1 more source

Host Cell Factors as Antiviral Targets in Arenavirus Infection

Viruses, 2012
Among the members of the Arenaviridae family, Lassa virus and Junin virus generate periodic annual outbreaks of severe human hemorrhagic fever (HF) in endemic areas of West Africa and Argentina, respectively.
Elsa B. Damonte, Luis A. Scolaro, Cybele C. García, Viviana Castilla, Florencia N. Linero, Federico Giovannoni, Claudia S. Sepúlveda   +6 more
doaj   +1 more source

Biological Activities of Junin Virus Proteins

Intervirology, 1980
In the Junin virus-infected cell, there is a soluble antigen (SAg), which we have detected by complement fixation.
Maria Ines de Mitri, Zulema M. de Martinez Segovia   +1 more
openaire   +1 more source

Antimicrobial peptides for novel antiviral strategies in the current post‐COVID‐19 pandemic

Journal of Peptide Science, Volume 30, Issue 1, January 2024.
This review describes the main physicochemical characteristics of antimicrobial peptides, with particular focus on peptides derived from amphibian skin. Summarizing the various antiviral activities of these peptides and the underlying mechanism, this review emphasizes the high potential of these small molecules for the development of new antiviral ...
Maria Rosa Loffredo, Lucia Nencioni, Maria Luisa Mangoni, Bruno Casciaro   +3 more
wiley   +1 more source

Analysis of the Cell Type-Dependence on the Arenavirus Z-Mediated Virus-Like Particle Production

Frontiers in Microbiology, 2020
Several arenaviruses are highly pathogenic to humans, causing hemorrhagic fever. Discovery of anti-arenavirus drug candidates is urgently needed, although the molecular basis of the host- and organ-specific pathogenicity remains to be fully elucidated ...
Patrick I. Mpingabo, Patrick I. Mpingabo, Shuzo Urata, Shuzo Urata, Jiro Yasuda, Jiro Yasuda, Jiro Yasuda   +6 more
doaj   +1 more source

Animal Models of Pathogenic New World Arenaviruses

Microorganisms
Since the emergence of Junín virus in 1953, pathogenic New World arenaviruses have remained a public health concern. These viruses, which also include Machupo virus, Guanarito virus, Sabiá virus, and Chapare virus, cause acute viral hemorrhagic fever and
Alexander V. Alvarado, Robert W. Cross, Thomas W. Geisbert, Courtney Woolsey   +3 more
doaj   +1 more source

Fiebres hemorrágicas por Arenavirus en Latinoamérica

Salud Uninorte, 2010
Las fiebres hemorrágicas virales producidas por Arenavirus incluyen a los virus endémicos en África (Lassa) y el virus de la coriomeningitis linfocítica (LCMV), de distribución mundial, y los Arenavirus del Nuevo Mundo o Complejo Tacaribe, que incluye a ...
Ella Soto, Salim Mattar
doaj  

Type I interferon underlies severe disease associated with Junín virus infection in mice

eLife, 2020
Junín virus (JUNV) is one of five New World mammarenaviruses (NWMs) that causes fatal hemorrhagic disease in humans and is the etiological agent of Argentine hemorrhagic fever (AHF).
Brady T Hickerson, Eric J Sefing, Kevin W Bailey, Arnaud J Van Wettere, Manuel L Penichet, Brian B Gowen   +5 more
doaj   +1 more source