Results 31 to 40 of about 3,174 (230)
Revista Peruana de Medicina Experimental y Salud Pública, 2015 The Argentine hemorrhagic fever (AHF) is a severe acute viral disease caused by the Junin virus of the Arenaviridae family. The AHF endemic area coincides geographically with the largest grain export agro-industrial complex of the country [Argentina ...
Ana Briggiler +6 more
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Effective oral favipiravir (T-705) therapy initiated after the onset of clinical disease in a model of arenavirus hemorrhagic Fever. [PDF]
PLoS Neglected Tropical Diseases, 2011 Lassa and Junín viruses are the most prominent members of the Arenaviridae family of viruses that cause viral hemorrhagic fever syndromes Lassa fever and Argentine hemorrhagic fever, respectively.
Michelle Mendenhall +6 more
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Nuclease Activity of the Junín Virus Nucleoprotein C-Terminal Domain
Viruses, 2023 The mammarenavirus Junín (JUNV) is the causative agent of Argentine hemorrhagic fever, a severe disease of public health concern. The most abundant viral protein is the nucleoprotein (NP), a multifunctional, two-domain protein with the primary role as ...
Alicia Armella Sierra +6 more
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Pathogens, 2015 Arenaviruses include multiple human pathogens ranging from the low-risk lymphocytic choriomeningitis virus (LCMV) to highly virulent hemorrhagic fever (HF) causing viruses such as Lassa (LASV), Junin (JUNV), Machupo (MACV), Lujo (LUJV), Sabia (SABV ...
Junjie Shao, Yuying Liang, Hinh Ly
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Single dose rVSVΔG-JUNVGP vaccine protects guinea pigs against lethal Junin virus challenge
npj Vaccines, 2021 Junin virus (JUNV) is a pathogen of biodefense importance due to its potential for aerosol transmission and mortality rates reaching 30%. Currently, there are no JUNV vaccines licensed by the United States Food and Drug Administration (FDA) for at-risk ...
Teresa E. Sorvillo +6 more
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Immunosuppression in Experimental Junin Virus Infection of Mice
Intervirology, 1980 The effects of cyclophosphamide (CY), anti-mouse thymocyte sera, oxisuran, and cytosine arabinoside were evaluated in adult and newborn mice infected with Junin virus. Treatment with CY was the most effective, Adult mice, which are not normally susceptible to intracerebral infection with 10(3) LD50 of Junin virus, were rendered susceptible by treatment
O A, Giovanniello +3 more
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Protection Against Junin Virus by Immunization with Live Tacaribe Virus
Experimental Biology and Medicine, 1965 SummaryAdult guinea pigs immunized with the live Tacaribe virus are able to resist challenge with a large dose of Junin virus to which they are normally susceptible. Sera from the Tacaribe virus-immunized guinea pigs contain abundant homologous antibody demonstrable by both complement-fixation and plaque neutralization tests.
N, TAURASO, A, SHELOKOV
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BioMed Research International, Volume 2026, Issue 1, 2026.The cross‐reactivity of substrates, modulators with other enzymes significantly reduces/prevents our ability to design such highly specific, that is, “one warhead–one target”, modulators. On the other hand, the potential “impasse” fuels repurposing of already developed drugs.
Monika I. Konaklieva +2 more
wiley +1 more source
PLoS Pathogens, 2021 Signal-regulatory protein alpha (SIRPA) is a well-known inhibitor of phagocytosis when it complexes with CD47 expressed on target cells. Here we show that SIRPA decreased in vitro infection by a number of pathogenic viruses, including New World and Old ...
Nicolás Sarute +6 more
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Arthropod ectoparasites of synanthropic rodents in northern‐central Italy
Medical and Veterinary Entomology, Volume 39, Issue 4, Page 787-793, December 2025.The presence of ectoparasites in synanthropic rodents in various Italian provinces was investigated. Eighty‐one Rattus norvegicus, 49 Rattus rattus and 10 Mus musculus were examined Polyplax spinulosa lice, Myobiidae mites, Laelaps echidninus and Notoedres muris were mainly recovered.
Filippo Maria Dini +3 more
wiley +1 more source