Results 11 to 20 of about 3,174 (230)

RIG-I enhanced interferon independent apoptosis upon Junin virus infection. [PDF]

open access: yesPLoS ONE, 2014
Junin virus (JUNV) is the etiological agent of Argentine hemorrhagic fever (AHF), a human disease with a high case-fatality rate. It is widely accepted that arenaviral infections, including JUNV infections, are generally non-cytopathic. In contrast, here
Olga A Kolokoltsova   +10 more
doaj   +1 more source

The Virus–Host Interplay in Junín Mammarenavirus Infection

open access: yesViruses, 2022
Junín virus (JUNV) belongs to the Arenaviridae family and is the causative agent of Argentine hemorrhagic fever (AHF), a severe human disease endemic to agricultural areas in Argentina.
Giovanna Lucrecia Gallo   +2 more
doaj   +1 more source

Junín Virus Pathogenesis and Virus Replication

open access: yesViruses, 2012
Junín virus, the etiological agent of Argentine hemorrhagic fever, causes significant morbidity and mortality. The virus is spread through the aerosolization of host rodent excreta and endemic to the humid pampas of Argentina.
Olga Kolokoltsova   +6 more
doaj   +1 more source

Luminescent reporter cells enable the identification of broad‐spectrum antivirals against emerging viruses

open access: yesJournal of Medical Virology, Volume 95, Issue 11, November 2023., 2023
Abstract The emerging viruses SARS‐CoV‐2 and arenaviruses cause severe respiratory and hemorrhagic diseases, respectively. The production of infectious particles of both viruses and virus spread in tissues requires cleavage of surface glycoproteins (GPs) by host proprotein convertases (PCs).
Karin Löw   +10 more
wiley   +1 more source

The knowns and unknowns of cardiac autoimmunity in viral myocarditis

open access: yesReviews in Medical Virology, Volume 33, Issue 6, November 2023., 2023
Abstract Myocarditis can result from various infectious and non‐infectious causes that can lead to dilated cardiomyopathy (DCM) and heart failure. Among the infectious causes, viruses are commonly suspected. But the challenge is our inability to demonstrate infectious viral particles during clinical presentations, partly because by that point, the ...
Kiruthiga Mone, Jay Reddy
wiley   +1 more source

Surface layer proteins in species of the family Lactobacillaceae

open access: yesMicrobial Biotechnology, Volume 16, Issue 6, Page 1232-1249, June 2023., 2023
Manuscript is focus on the prediction of slp genes within the Lactobacillaceae family and interconnection between the two different modular SLP domain organizations of the new reclassified genera. SLP applications are reviewed regarding heterologous display, pathogen exclusion, immunostimulation, and metal binding. Abstract The S‐layer or surface layer
M. Mercedes Palomino   +5 more
wiley   +1 more source

Standardization of an ELISA test using a recombinant nucleoprotein from the Junin virus as the antigen and serological screening for arenavirus among the population of Nova Xavantina, State of Mato Grosso Padronização de um teste de ELISA utilizando a nucleoproteína recombinante de vírus Junin como antígeno e triagem sorológica para Arenavírus na população de Nova Xavantina, Estado do Mato Grosso

open access: yesRevista da Sociedade Brasileira de Medicina Tropical, 2010
INTRODUCTION: Arenavirus hemorrhagic fever is a severe emerging disease. METHODS: Considering that the levels of antibodies against arenavirus in the Brazilian population are completely unknown, we have standardized an ELISA test for detecting IgG ...
Alex Martins Machado   +5 more
doaj   +1 more source

The Estimation of Efficacy of Nonspecific Medications Against Hemorrhagic Fevers Caused by Arenaviruses

open access: yesАнтибиотики и Химиотерапия, 2023
The article presents an analysis of studies assessing the effectiveness of new nonspecific medications against hemorrhagic fevers caused by arenaviruses.
Т. Е. Sizikova   +2 more
doaj   +1 more source

Structural basis for recognition and regulation of arenavirus polymerase L by Z protein

open access: yesNature Communications, 2021
Junin virus (JUNV) causes Argentine hemorrhagic fever and encodes the large protein (L) of the RNA dependent RNA polymerase (RdRp) and its regulator, the matrix zinc-binding protein (Z).
Huiling Kang   +8 more
doaj   +1 more source

Contrasting Modes of New World Arenavirus Neutralization by Immunization-Elicited Monoclonal Antibodies

open access: yesmBio, 2022
Transmission of the New World hemorrhagic fever arenaviruses Junín virus (JUNV) and Machupo virus (MACV) to humans is facilitated, in part, by the interaction between the arenavirus GP1 glycoprotein and the human transferrin receptor 1 (hTfR1).
Weng M. Ng   +9 more
doaj   +1 more source

Home - About - Disclaimer - Privacy