Results 101 to 110 of about 675,632 (363)
Ebola virus VP30 and nucleoprotein interactions modulate viral RNA synthesis [PDF]
, 2017 Ebola virus (EBOV) is an enveloped negative-sense RNA virus that causes sporadic outbreaks with high case fatality rates. Ebola viral protein 30 (eVP30) plays a critical role in EBOV transcription initiation at the nucleoprotein (eNP) gene, with ...
Amarasinghe, Gaya K +6 more
core +2 more sources
Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence
Molecular Oncology, EarlyView.The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova +18 more
wiley +1 more source
A Functional Role of Fibroblast Growth Factor Receptor 1 (FGFR1) in the Suppression of Influenza A Virus Replication. [PDF]
PLoS ONE, 2015 Influenza A virus causes annual epidemics and occasional pandemics in humans. Here, we investigated four members of the fibroblast growth factor receptor (FGFR) family; FGFR1 to 4, and examined their expression patterns in human lung epithelial cells ...
Xin Liu +6 more
doaj +1 more source
Riboswitching on RNA virus replication [PDF]
Proceedings of the National Academy of Sciences, 2007 Positive-strand RNA viruses direct different virus-specific processes during their infection of host cells. Fundamental events such as viral RNA genome replication are controlled by viral regulatory RNA elements (REs). Here, we have investigated the possibility of specifically modulating the action of a viral RE using RNA aptamer technology.
K. Andrew White, Sheng Wang
openaire +3 more sources
Emerging Microbes and Infections, 2022 Japanese encephalitis virus (JEV), an important neurotropic pathogen, belongs to the genus Flavivirus of the family Flaviviridae and has caused huge threat to public health.
Qiu-Yan Zhang +12 more
doaj +1 more source
Lipids and RNA virus replication [PDF]
Current Opinion in Virology, 2014 Most viruses rely heavily on their host machinery to successfully replicate their genome and produce new virus particles. Recently, the interaction of positive-strand RNA viruses with the lipid biosynthetic and transport machinery has been the subject of intense investigation.
Lorena Sanchez-Felipe, Kouacou V. Konan
openaire +2 more sources
, 2011 This chapter describes virus replication. Before the development of in vitro cell culture techniques, all viruses had to be propagated in their natural host. For bacterial viruses, this was a relatively simple process that permitted an earlier development of laboratory research methods than was possible with plant or animal viruses. For animal viruses,
openaire +1 more source
DNA Virus Replication Compartments [PDF]
Journal of Virology, 2014 ABSTRACTViruses employ a variety of strategies to usurp and control cellular activities through the orchestrated recruitment of macromolecules to specific cytoplasmic or nuclear compartments. Formation of such specialized virus-induced cellular microenvironments, which have been termed viroplasms, virus factories, or virus replication centers ...
Melanie Schmid +3 more
openaire +3 more sources
mBioThe integration of HPV DNA into human chromosomes plays a pivotal role in the onset of papillomavirus-related cancers. HPV DNA integration often occurs by linearizing the viral DNA in the E1/E2 region, resulting in the loss of a critical viral early ...
Lulu Yu +9 more
doaj +1 more source
PLoS Pathogens, 2021 Adeno-associated virus (AAV) genome replication only occurs in the presence of a co-infecting helper virus such as adenovirus type 5 (AdV5) or herpes simplex virus type 1 (HSV-1).
Anita Felicitas Meier +5 more
doaj +1 more source