Results 11 to 20 of about 675,632 (363)
Stability of a stochastically perturbed model of intracellular single-stranded RNA virus replication [PDF]
Replication of single-stranded RNA virus can be complicated, compared to that of double-stranded virus, as it require production of intermediate antigenomic strands that then serve as template for the genomic-sense strands.
Elena, Santiago F.+2 more
core +2 more sources
Summary Although 84 to 99% of seed virus was adsorbed to chorioallantoic membranes of chick embryos within 2 hr after infection, only 1% or less of the introduced virus was recoverable during the latent period. The length of this latent period was found to be at least 20 hr.
L, TREAGAN, J, FONG
openaire +3 more sources
Junín Virus Pathogenesis and Virus Replication [PDF]
Junín virus, the etiological agent of Argentine hemorrhagic fever, causes significant morbidity and mortality. The virus is spread through the aerosolization of host rodent excreta and endemic to the humid pampas of Argentina. Recently, significant progress has been achieved with the development of new technologies (e.g.
Clarence J. Peters+6 more
openaire +5 more sources
Evolutionary Dynamics of Giant Viruses and their Virophages [PDF]
Giant viruses contain large genomes, encode many proteins atypical for viruses, replicate in large viral factories, and tend to infect protists. The giant virus replication factories can in turn be infected by so called virophages, which are smaller ...
Anderson+39 more
core +3 more sources
Mechanism of Viral Glycoprotein Targeting by Membrane-Associated RING-CH Proteins
Viral envelope glycoproteins are an important structural component on the surfaces of enveloped viruses that direct virus binding and entry and also serve as targets for the host adaptive immune response.
Cheng Man Lun+4 more
doaj +1 more source
Although combination antiretroviral (ARV) therapy is highly effective in controlling the progression of HIV disease, drug resistance can be a major obstacle. Recent findings suggest that resistance can develop without ARV target gene mutations.
Yuta Hikichi+7 more
doaj +1 more source
Patch formation driven by stochastic effects of interaction between viruses and defective interfering particles [PDF]
Defective interfering particles (DIPs) are virus-like particles that occur naturally during virus infections. These particles are defective, lacking essential genetic materials for replication, but they can interact with the wild-type virus and potentially be used as therapeutic agents.
arxiv +1 more source
The MARCH family of RING-finger E3 ubiquitin ligases comprise 11 members that have been reported to play a variety of roles in the downregulation of cell-surface proteins involved in adaptive immunity.
Cheng man Lun+2 more
doaj +1 more source
Background The continued persistence of HIV-1 as a public health concern due to the lack of a cure calls for the development of new tools for studying replication of the virus.
James Kirui, Eric O. Freed
doaj +1 more source
SARS-CoV-2: from its discovery to genome structure, transcription, and replication
SARS-CoV-2 is an extremely contagious respiratory virus causing adult atypical pneumonia COVID-19 with severe acute respiratory syndrome (SARS). SARS-CoV-2 has a single-stranded, positive-sense RNA (+RNA) genome of ~ 29.9 kb and exhibits significant ...
Ayslan Castro Brant+4 more
doaj +1 more source