Results 21 to 30 of about 760,800 (362)
, 2017 The replication processes used by individual viruses is highly variable. However, all viruses must attach to a susceptible host cell, enter the cell, disassemble the virus particle (uncoating), replicate its own genetic material and express the associated proteins, assemble new virus particles, and escape from the infected cell (release).
Burrell, Christopher J. +2 more
openaire +2 more sources
mBio, 2021 Human immunodeficiency virus type 1 (HIV-1) Gag selects and packages the HIV RNA genome during virus assembly. However, HIV-1 RNA constitutes only a small fraction of the cellular RNA.
Alice Duchon +9 more
doaj +1 more source
Replication enhancer elements within the open reading frame of tick-borne encephalitis virus and their evolution within the Flavivirus genus [PDF]
, 2011 We provide experimental evidence of a replication enhancer element (REE) within the capsid gene of tick-borne encephalitis virus (TBEV, genus Flavivirus).
Buckley, A. +5 more
core +3 more sources
Hepatitis E Virus Replication [PDF]
Viruses, 2019 Hepatitis E virus (HEV) is a small quasi-enveloped, (+)-sense, single-stranded RNA virus belonging to the Hepeviridae family. There are at least 20 million HEV infections annually and 60,000 HEV-related deaths worldwide. HEV can cause up to 30% mortality in pregnant women and progress to liver cirrhosis in immunocompromised individuals and is ...
Robert LeDesma +2 more
openaire +3 more sources
Viruses, 2018 Tetherin is an interferon-inducible antiviral protein that inhibits the release of a broad spectrum of enveloped viruses by retaining virions at the surface of infected cells.
Abdul A. Waheed +3 more
doaj +1 more source
Enhancement of vaccinia virus based oncolysis with histone deacetylase inhibitors [PDF]
, 2010 Histone deacetylase inhibitors (HDI) dampen cellular innate immune response by decreasing interferon production and have been shown to increase the growth of vesicular stomatitis virus and HSV.
Atkins, H +15 more
core +1 more source
Junín Virus Pathogenesis and Virus Replication [PDF]
Viruses, 2012 Junín virus, the etiological agent of Argentine hemorrhagic fever, causes significant morbidity and mortality. The virus is spread through the aerosolization of host rodent excreta and endemic to the humid pampas of Argentina. Recently, significant progress has been achieved with the development of new technologies (e.g.
Olga Kolokoltsova +6 more
openaire +3 more sources
Differential effects of lipid biosynthesis inhibitors on Zika and Semliki Forest viruses [PDF]
, 2017 The recent outbreak of infection with Zika virus (ZIKV; Flaviviridae) has attracted attention to this previously neglected mosquito-borne pathogen and the need for efficient therapies.
Donald, Claire L. +4 more
core +1 more source
HIV Infected T Cells Can Proliferate in vivo Without Inducing Expression of the Integrated Provirus
Frontiers in Microbiology, 2019 BackgroundHIV-1 proviruses can persist during ART in clonally-expanded populations of CD4+ T cells. To date, few examples of an expanded clones containing replication-competent proviruses exist, although it is suspected to be common.
Andrew Musick +18 more
doaj +1 more source
Phenotypic hypersusceptibility to multiple protease inhibitors and low replicative capacity in patients who are chronically infected with human immunodeficiency virus type 1 [PDF]
, 2005 Increased susceptibility to the protease inhibitors saquinavir and amprenavir has been observed in human immunodeficiency virus type 1 (HIV-1) with specific mutations in protease (V82T and N88S).
Clotet, B +7 more
core +2 more sources