Results 41 to 50 of about 753,101 (359)
The Replication of Semliki Forest Virus
Journal of General Virology, 1974 Summary Using polyacrylamide gel electrophoresis, column chromatography on CF11 cellulose and salt precipitation, together with ribonuclease treatment, we have identified, in chick cells infected with Semliki Forest virus, four species of virus-specified single-stranded RNA, three species of double-stranded RNA and a multi-stranded RNA species. The mol.
B A, Martin, D C, Burke
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Autophagy induction regulates influenza virus replication in a time-dependent manner [PDF]
, 2017 Autophagy plays a key role in host defence responses against microbial infections by promoting degradation of pathogens and participating in acquired immunity.
Abdoli, Asghar +12 more
core +1 more source
Role of Lipids in Virus Replication [PDF]
Cold Spring Harbor Perspectives in Biology, 2011 Viruses intricately interact with and modulate cellular membranes at several stages of their replication, but much less is known about the role of viral lipids compared to proteins and nucleic acids. All animal viruses have to cross membranes for cell entry and exit, which occurs by membrane fusion (in enveloped viruses), by transient local disruption ...
Maier, Lorizate, Hans-Georg, Kräusslich
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mBioKaposi’s sarcoma-associated herpesvirus (KSHV) encodes an RNA-binding protein ORF57 in lytic infection. Using an optimized CLIP-seq in this report, we identified ORF57-bound transcripts from 544 host protein-coding genes.
Vladimir Majerciak +6 more
doaj +1 more source
Retrovirology, 2017 The first responders of human antiviral immunity are components of the intrinsic immune response that reside within each and every one of our cells.
Guoli Shi +2 more
doaj +1 more source
Human papillomavirus E2 regulates SRSF3 (SRp20) to promote capsid protein expression in infected differentiated keratinocytes [PDF]
, 2016 The human papillomavirus (HPV) life cycle is tightly linked to differentiation of the infected epithelial cell suggesting a sophisticated interplay between host cell metabolism and virus replication.
Beemon, K. L. +5 more
core +2 more sources
Cold Spring Harbor Perspectives in Medicine, 2019 Replication and amplification of the viral genome is a key process for all viruses. For hepatitis C virus (HCV), a positive-strand RNA virus, amplification of the viral genome requires the synthesis of a negative-sense RNA template, which is in turn used for the production of new genomic RNA. This process is governed by numerous proteins, both host and
Keisuke, Tabata +2 more
openaire +3 more sources
The role of fibroblast growth factors in cell and cancer metabolism
FEBS Letters, EarlyView.Fibroblast growth factor (FGF) signaling regulates crucial signaling cascades that promote cell proliferation, survival, and metabolism. Therefore, FGFs and their receptors are often dysregulated in human diseases, including cancer, to sustain proliferation and rewire metabolism.
Jessica Price, Chiara Francavilla
wiley +1 more source
Defined mutations in the 5' nontranslated sequence of Sindbis virus RNA [PDF]
, 1990 We have constructed 24 deletion mutants which contain deletions of from 1 to 15 nucleotides in the 5' nontranslated region of Sindbis virus RNA and tested the effect of these mutations on virus replication.
Niesters, Hubert G. M. +1 more
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Ebola virus VP30 and nucleoprotein interactions modulate viral RNA synthesis [PDF]
, 2017 Ebola virus (EBOV) is an enveloped negative-sense RNA virus that causes sporadic outbreaks with high case fatality rates. Ebola viral protein 30 (eVP30) plays a critical role in EBOV transcription initiation at the nucleoprotein (eNP) gene, with ...
Amarasinghe, Gaya K +6 more
core +2 more sources