Results 181 to 190 of about 13,089 (196)

p38 MAPK Signaling Enhances Reovirus Replication by Facilitating Efficient Virus Entry, Virus Capsid Uncoating and Post-Uncoating Steps

2022
Abstract Mammalian orthoreovirus serotype 3 Dearing an orphan human virus currently being pursued as an oncolytic virus in multiple phase I/II clinical trials. Previous clinical trials have emphasized the importance of patient pre-screening for prognostic markers to improve therapeutic success.
Adil Mohamed, Maya Shmulevitz
openaire   +1 more source

Role of ribosomes in Semliki Forest virus nucleocapsid uncoating

Journal of Virology, 1992
The mechanism by which Semliki Forest virus nucleocapsids are uncoated was analyzed in living cells and in vitro. In BHK-21 cells, uncoating occurred with virtually complete efficiency within 1 to 2 min after the nucleocapsids entered the cytoplasm. It was inhibited by monensin, which blocks nucleocapsid penetration from endosomes.
I, Singh, A, Helenius
openaire   +2 more sources

Rimantadine hydrochloride blocks the second step of influenza virus uncoating

Archives of Virology, 1980
Two steps of influenza virus A/WSN uncoating in MDCK cells are described. The products of the first step are cores which accumulate in the nuclear-associated cytoplasm. The products of the second step are ribonucleoproteins which penetrate the nuclei. Rimantadine blocks the second step without interfering with the first one.
A G, Bukrinskaya, N K, Vorkunova, R A, Narmanbetova   +2 more
openaire   +2 more sources

Monkeypox virus (MPV) II. Uncoating and nucleic acid synthesis

Archiv f�r die gesamte Virusforschung, 1972
The percentage of uncoating of monkeypox virus (MPV) in CV-1 cells measured by sensitivity of viral DNA to deoxyribonuclease was 24, 46, 53, 48, and 54, at respective 2, 3, 4, 5, and 6 hours post infection. Cores began to appear 1/2 to 1 hour post infection and subsided 3–4 hours post infection to yield naked DNA.
T M, Yau, H, Rouhandeh
openaire   +2 more sources

Hepatitis B virus nucleocapsid uncoating: biological consequences and regulation by cellular nucleases

Emerging Microbes and Infections, 2021
Liudi Tang, Junjun Cheng, Tianlun Zhou   +2 more
exaly  

Region-Specific Hepatitis B Virus Genome Exposure from Nucleocapsid Modulated by Capsid Linker Sequence and Inhibitor: Implications for Uncoating

Journal of Virology, 2022
Xiuji Cui, Kuancheng Liu, Jianming Hu
exaly  

Mechanism of Uncoating of Influenza B Virus in MDCK Cells: Action of Chloroquine

Journal of General Virology, 1983
Hiizu Aoki, Tatsuya Tsurumi, Yasuo Sugiura   +2 more
exaly  

Real-time dissection of dynamic uncoating of individual influenza viruses

Proceedings of the National Academy of Sciences of the United States of America, 2019
Qin Li, Xiaowei Zhang, Xian-En Zhang
exaly  

Infection by and Uncoating of Virus Particles

2006
openaire   +1 more source

Uncoating of Human Immunodeficiency Virus Type 1 Requires Prolyl Isomerase Pin1

Journal of Biological Chemistry, 2010
Shogo Misumi, Naoki Kishimoto, Nobutoki Takamune   +2 more
exaly