Journal of Animal Ecology, EarlyView.We bridge micro‐ and macroparasite theory with a model tracking pathogen load heterogeneity. By incorporating load‐dependent mortality and within‐host pathogen growth, we show how pathogen load aggregation alters disease prevalence, host suppression effects, and virulence evolution, providing insights for managing complex infectious disease like ...
Ruijiao Sun +3 more
wiley +1 more source
Hotter, faster, sicker? Warming shifts the cost of infection from individuals to populations
Journal of Animal Ecology, EarlyView.This study examines how temperature alters disease impacts across biological scales in a host–pathogen system. We found infected hosts appear healthiest at warm temperatures, yet populations suffer most. This suggests climate warming may intensify disease impacts for populations in ways traditional individual‐level virulence metrics fail to predict ...
Nathan J. Butterworth +2 more
wiley +1 more source
Deciphering pUL10's mastery in duck plague virus virulence: dual coordination of host immunity and viral replication. [PDF]
Poult SciLi C, Wang M, Cheng A.
europepmc +1 more source
Between‐species contagion drives HPAI transmission and mass mortality in seabirds
Journal of Animal Ecology, EarlyView.Modelling the unprecedented avian panzootic caused by High‐Pathogenicity Avian Influenza (HPAI) across the Northeast Atlantic gannet breeding metapopulation, we estimated 28% (95% CI: 21%–34%) HPAI‐related mortality. Large‐scale outbreak initiation was best explained by external infection sources, most likely, other seabird species.
Jason Matthiopoulos +5 more
wiley +1 more source
An accumulated mutation gained in mosquito cells enhances Zika virus virulence and fitness in mice. [PDF]
J VirolFan X-X +8 more
europepmc +1 more source
Russian wheat aphid: a model for genomic plasticity and a challenge to breeders
Insect Science, EarlyView.Invasive foundress finds suitable habitat and reproduces through pathogenesis. Wingless females produce life offspring quickly, which leads to high population densities. High population densities result in competition, which may induce epigenetic changes and wing development for dispersal.
Astrid Jankielsohn +8 more
wiley +1 more source
Peste des petits ruminants virus virulence is associated with an early inflammatory profile in the tonsils and cell cycle arrest in lymphoid tissue. [PDF]
Microbiol SpectrEloiflin R-J +8 more
europepmc +1 more source
Host phylogenetic distance drives trends in virus virulence and transmissibility across the animal-human interface. [PDF]
Philos Trans R Soc Lond B Biol Sci, 2019 Guth S, Visher E, Boots M, Brook CE.
europepmc +1 more source
Iflaviruses in arthropods: when small is mighty
Insect Science, EarlyView.Many arthropod species harbor iflaviruses, which often cause covert (asymptomatic) infections, but may still affect host fitness. We review the impact of iflaviruses on arthropod fitness, immunity, behaviour as well as the iflavirus’ host range, transmission, tissue tropism and the interactions with other microorganisms within arthropods.
Annamaria Mattia +3 more
wiley +1 more source
Effect of the microbiome on pathogen susceptibility across four Drosophilidae species
Insect Science, EarlyView.Four Drosophilidae species were used to investigate how variation in the host microbiome influences susceptibility to infection. Microbial composition and abundance differed among species and treatments. The effects of microbiome manipulation on host survival were both species‐ and pathogen‐specific.
Hongbo Sun, Ben Longdon, Ben Raymond
wiley +1 more source