Results 181 to 190 of about 1,547,632 (301)

16S/18S metabarcoding versus culture for aetiological assessment in infectious keratitis: A prospective paired‐sample study

Acta Ophthalmologica, EarlyView.
Abstract Purpose Infectious keratitis (IK) is a vision‐threatening condition with diverse microbial aetiologies, yet conventional culture‐based diagnostics often have limited sensitivity. We investigated whether 16S/18S rRNA amplicon‐based next‐generation sequencing (NGS) can enhance aetiological assessment when used alongside standard microbiological ...
Sandra M. Skovdal, Christen Rune Stensvold, Henrik Vedel Nielsen, Stine Elkjær Nielsen, Jesper Hjortdal, Lise Kristensen, Anders Ivarsen   +6 more
wiley   +1 more source

An accumulated mutation gained in mosquito cells enhances Zika virus virulence and fitness in mice. [PDF]

J Virol
Fan X-X, Li R-T, Zhu Y-B, Chen Q, Li X-F, Cao T-S, Zhao H, Cheng G, Qin C-F.   +8 more
europepmc   +1 more source

Maternal factors from a parasitoid wasp mediate hyperparasitoid attraction to parasitized caterpillars

Ecological Entomology, EarlyView.
The parasitoid‐associated polydnavirus CgPDV, but not venom alone, significantly increases the attractiveness of Pieris brassicae caterpillars to the hyperparasitoid Baryscapus galactopus at close range. Naturally parasitized caterpillars elicit stronger hyperparasitoid attraction than any injection treatment, indicating that additional factors beyond ...
Yuhan Liu, Mitchel E. Bourne, Maximilien A. C. Adam, Sarah N. Kalisvaart, Erik H. Poelman, Nina Xiaoning Zhang   +5 more
wiley   +1 more source

Interaction between SARS-CoV PBM and Cellular PDZ Domains Leading to Virus Virulence. [PDF]

Viruses
Honrubia JM, Valverde JR, Muñoz-Santos D, Ripoll-Gómez J, de la Blanca N, Izquierdo J, Villarejo-Torres M, Marchena-Pasero A, Rueda-Huélamo M, Nombela I, Ruiz-Yuste M, Zuñiga S, Sola I, Enjuanes L.   +13 more
europepmc   +1 more source

Host phylogenetic distance drives trends in virus virulence and transmissibility across the animal-human interface. [PDF]

Philos Trans R Soc Lond B Biol Sci, 2019
Guth S, Visher E, Boots M, Brook CE.
europepmc   +1 more source

SERTA Domain Containing Protein 1 (SERTAD1) Interacts with Classical Swine Fever Virus Structural Glycoprotein E2, Which Is Involved in Virus Virulence in Swine. [PDF]

Viruses, 2020
Vuono EA, Ramirez-Medina E, Azzinaro P, Berggren KA, Rai A, Pruitt S, Silva E, Velazquez-Salinas L, Borca MV, Gladue DP.   +9 more
europepmc   +1 more source

T‐Cell Response After SARS‐CoV‐2 Vaccination in Patients With Hematological Malignancy

European Journal of Haematology, EarlyView.
ABSTRACT Patients with hematologic malignancies (HM) often mount poor humoral responses to SARS‐CoV‐2 vaccination due to their immunocompromised status. Protection against severe COVID‐19 is strongly related to cellular immunity, yet vaccine‐induced T‐cell responses remain incompletely characterized.
L. S. Boerenkamp, N. Scheffers, L. Brandts, G. N. Y. van Gorkom, C. R. Pothast, M. H. M. Heemskerk, L. Wieten, C. H. M. J. Van Elssen   +7 more
wiley   +1 more source

Peste des petits ruminants virus virulence is associated with an early inflammatory profile in the tonsils and cell cycle arrest in lymphoid tissue. [PDF]

Microbiol Spectr
Eloiflin R-J, Grau-Roma L, Lasserre V, Python S, Talker S, Totte P, García-Nicolás O, Summerfield A, Bataille A.   +8 more
europepmc   +1 more source

Rule-based meta-analysis reveals the major role of PB2 in influencing influenza A virus virulence in mice. [PDF]

BMC Genomics, 2019
Ivan FX, Kwoh CK.
europepmc   +1 more source

Catalysis and allostery in bacterial ATP phosphoribosyltransferases

The FEBS Journal, EarlyView.
ATP phosphoribosyltransferase (ATPPRT) catalyses the first reaction of L‐histidine biosynthesis. L‐Histidine allosterically inhibits ATPPRT to regulate this energy‐intensive pathway in histidine‐synthesising organisms, such as bacteria, archaea and plants.
Lillian G. Bates, Rafael G. da Silva
wiley   +1 more source