Results 171 to 180 of about 3,777,037 (252)

The Physician Global Assessment as a Proxy for Photoaging: Validation in an Observational Real‐World Cohort Using SCINEXA as the Reference Standard

open access: yesJEADV Clinical Practice, EarlyView.
ABSTRACT Background Photoaging is a chronic skin condition caused by cumulative ultraviolet exposure superimposed on intrinsic aging. Although the SCore of INtrinsic and EXtrinsic skin Aging (SCINEXA) is a validated multidimensional instrument for assessing photoaging, the Physician Global Assessment (PGA) is a simpler clinician‐reported measure whose ...
Ewout Baerveldt   +6 more
wiley   +1 more source

Metabolic Dysfunction‐Associated Steatotic Liver Disease and Obesity: Pathogenesis, Diagnostics, Risk Stratification, and Therapeutic Approach

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Metabolic dysfunction‐associated steatotic liver disease (MASLD) has emerged as the most prevalent chronic liver disease worldwide, closely linked to the global rising incidence of obesity and metabolic syndrome. This review synthesizes current evidence on the pathogenesis, gut–liver axis, and multidisciplinary management of MASLD within the ...
Beom Kyung Kim
wiley   +1 more source

Estimated Body Fat Percentage and Triglyceride‐Glucose Index for Identifying MASLD in Lean Asian Adults: A Cross‐Sectional Analysis

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Metabolic dysfunction‐associated steatotic liver disease (MASLD) is increasingly prevalent among lean Asian populations, yet effective strategies for identifying high‐risk individuals remain limited. We investigated the associations of body fat percentage (BF%) and the triglyceride‐glucose (TyG) index with lean MASLD and evaluated their ...
Xiang‐Ran Kong   +4 more
wiley   +1 more source

Terazosin Attenuates Neuronal Pyroptosis by Regulating the Mitochondrial ROS/NLRP3 Inflammasome Axis Through Mitophagy in Cerebral Ischemia–Reperfusion Injury

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Cerebral ischemia–reperfusion injury (CI/RI) is a major cause of secondary neuronal damage following ischemic stroke. This study investigated whether terazosin (TZ) exerts neuroprotective effects by regulating mitophagy and the reactive oxygen species (ROS)/NOD‐like receptor protein 3 (NLRP3) inflammasome axis.
Wei Wang   +5 more
wiley   +1 more source

Determinants of Early Renal Function Recovery After TIPS in Patients With Portal Hypertension

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Renal dysfunction frequently occurs in patients with portal hypertension and is linked to unfavorable clinical outcomes. Transjugular intrahepatic portosystemic shunt (TIPS) has the potential to enhance renal perfusion through portal decompression; however, factors predicting early improvement in renal function remain insufficiently defined ...
Meng Jia   +6 more
wiley   +1 more source

Metabolic Syndrome and Dementia Risk in Older Adults: A Narrative Review

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Dementia is a major global health issue in aging societies. Metabolic syndrome (MetS), a cluster of metabolic abnormalities, has been proposed as a modifiable risk factor for dementia, although existing evidence remains inconsistent. This review examined recent studies on the association between MetS and dementia risk in older adults.
Hyojin Park   +2 more
wiley   +1 more source

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