Results 191 to 200 of about 3,777,037 (252)

Recent Advances in Exosome‐Based Nanodelivery Systems for Traumatic Brain Injury Treatment

Med Research, EarlyView.
An overview of functional modification, therapeutic effects, molecular composition, and delivery strategies for exosomes. ABSTRACT Traumatic brain injury (TBI) is a highly heterogeneous neurological condition with extremely high rates of mortality and disability.
Jue Zhu, Weiquan Liao, Ziqi Lian, Mengdan Zhang, Chenxing Wang, Xingjia Zhu, Lin Zhang, Jian Chen, Zhichao Lu, Peipei Gong   +9 more
wiley   +1 more source

Visceral Adiposity Index in Relation to Rotterdam Phenotypes of Polycystic Ovary Syndrome. [PDF]

Biomedicines
Pluta D, Staśczak A, Stokowy T, Migacz M, Kochman K, Holecki M.   +5 more
europepmc   +1 more source

Protecting CEACAM1 Expression Prevents Diet‐Induced Metabolic Dysfunction and Hepatic Fibrosis in Male Mice

Obesity, EarlyView.
ABSTRACT Objective High‐fat diet represses Ceacam1 transcription via a PPARα‐mediated mechanism to cause insulin resistance before inflammation develops. The current study investigated whether mutating PPRE‐RXRα in Ceacam1 promoter prevents diet‐induced metabolic abnormalities and hepatic fibrosis in male C57BL6/J mice.
Raziyeh Abdolahipour, Saja S. Khuder, William M. Philbrick, Agnes O. Portuphy, Getachew D. Belew, Hatem G. Fallouh, Harrison T. Muturi, Boyeon Kim, Jason K. Kim, Sonia M. Najjar   +9 more
wiley   +1 more source

Age-adjusted visceral adiposity index as a predictor of chronic kidney disease: insights from NHANES 2007-2018. [PDF]

Ren Fail
Yan B, Yuan R, Yin L, Huang S.
europepmc   +1 more source

Compositional Data Analysis of Relative Body Mass and Physical Function Using the Relative Shift Approach

Obesity, EarlyView.
ABSTRACT Objective The purpose of this study was to present the novel relative shift approach for compositional data analysis of body composition as a predictor for gait speed and to compare it to existing methods. Methods Body composition was quantified from dual‐energy x‐ray absorptiometry in 145 older adults living with obesity.
Daniel P. Beavers, Lauren S. Roe, Yutong Li, Katarina L. Dobrosky, Ian Janssen, Kristen M. Beavers   +5 more
wiley   +1 more source

The association between visceral adiposity index and female stress urinary incontinence: the NHANES 2013 to 2018. [PDF]

Medicine (Baltimore)
Sun D, Hou C, Zhu X, Xie B, He H, Wang Y.   +5 more
europepmc   +1 more source

Depot‐Specific Insulin Receptor Isoform Dynamics During Human Adipose‐Derived Stem Cell Adipogenesis

Obesity, EarlyView.
Absolute quantification reveals depot‐specific insulin receptor (IR) isoform signatures in human adipose stem cells, with subcutaneous cells enriched in IRa and exhibiting greater adipogenic capacity and insulin responsiveness. The emergence of IR‐negative adipocytes highlights partially receptor‐independent pathways regulating human adipogenesis ...
Valentina Annamaria Genchi, Celeste Lauriola, Cristina Caccioppoli, Rossella D'Oria, Nicola Marrano, Giuseppina Biondi, Sebastio Perrini, Annalisa Natalicchio, Luigi Laviola, Francesco Giorgino, Angelo Cignarelli   +10 more
wiley   +1 more source

Association between visceral adiposity index and endometriosis: a population-based study. [PDF]

Front Nutr
Zhang J, Zhang Q, Chu T, Chen X, Zhou H, Xu D, Dong C, Wu Y.   +7 more
europepmc   +1 more source

The role of tryptophan hydroxylase‐1 in metabolic dysfunction‐associated steatotic liver disease

Pediatric Investigation, EarlyView.
Silencing hepatic tryptophan hydroxylase 1 (TPH1) alleviated diet‐induced steatotic liver disease by reducing lipid accumulation, oxidative stress, inflammation, fibrosis, and hepatocyte apoptosis. These protective effects were mediated, at least in part, through restoration of Parkin‐dependent mitochondrial autophagy, identifying hepatic TPH1 as a ...
Shuangzhen Jia, Xiaolin Ye, Zhaoxia Wang, Jie Wu   +3 more
wiley   +1 more source

The mediating role of fasting plasma glucose and systolic blood pressure in the association between Chinese visceral adiposity index and carotid atherosclerosis: a cross-sectional study. [PDF]

Sci Rep
Qu M, Qu Y, Luo Y, Huang H.
europepmc   +1 more source