Results 31 to 40 of about 3,777,037 (252)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

The Relationship Between Epicardial Adipose Tissue and Visceral Adiposity Indexes in Individuals Without Established Atherosclerotic Cardiovascular Disease and Diabetes Mellitus

Endocrinology Research and Practice, 2023
Objective: Visceral adipose tissue performs an important role in the development of atherosclerotic cardiovascular disease. Expressing its close association with epicardial adipose tissue simplifies the understanding of visceral adipose tissue in terms ...
Abdulrahman Naser, Khagani Isgandarov, Tolga Sinan Güvenç, İbrahim Demir, Murat Kirişçi, Müslüm Şahin, Rengin Çetin Güvenç   +6 more
doaj  

Assessing Visceral Obesity and Abdominal Adipose Tissue Distribution in Healthy Populations Based on Computed Tomography: A Large Multicenter Cross-Sectional Study

Frontiers in Nutrition, 2022
ObjectiveAbdominal adipose is closely related to many endocrine and metabolic diseases. The aim of this study was to analyze the distribution of abdominal adipose tissue in a healthy population in northern China determined by abdominal computed ...
Ming Kong, Manman Xu, Ying Zhou, Nan Geng, Ning Lin, Wenyan Song, Shanshan Li, Yuetong Piao, Zuoqing Han, Rong Guo, Chao Yang, Nan Luo, Zhong Wang, Lei Ma, Quanxiao Xu, Lili Wang, Wanchun Qiu, Junfeng Li, Daimeng Shi, Eddie C. Cheung, Eddie C. Cheung, Rongkuan Li, Yu Chen, Zhongping Duan   +23 more
doaj   +1 more source

Separate and combined associations of body-mass index and abdominal adiposity with cardiovascular disease: collaborative analysis of 58 prospective studies [PDF]

, 2011
BACKGROUND: Guidelines differ about the value of assessment of adiposity measures for cardiovascular disease risk prediction when information is available for other risk factors. We studied the separate and combined associations of body-mass index (BMI),
Nordestgaard, Borge G., Stehouwer, Coen; id_orcid, Kaptoge, S., Danesh, J, Wood, Angela M., Thompson, Alex, Sattar, N, Thompson, A, Wormser, D, Emerging Risk Factors Collaboration, Risérus, Ulf,, Salomma, V, Sarwar, N, Danesh, J., Wood, Angela M, Pennells, L, Ärnlöv, Johan,, Woodward, M., Salomaa, Veikko, Sundström, Johan,, Thompson, S.G., Kaptoge, S, Tybjærg-Hansen, Anne, Wormser, D., Ridker, P, Thompson, Simon G, null The Emerging Risk Factors Collaboration, Woodward, Mark, Kizer, Jorge R, Frikke-Schmidt, Ruth, Nordestgaard, BG, Kaptoge, Stephen, Salomaa, V, Lawlor, DA, Eriksson, Henry,, Sarwar, Nadeem, Wood, AM, Kizer, Jorge R., Pennells, Lisa, Stevens, June, Pennells, L., Whitlock, G, Salomaa, V., Nordestgaard, B.G., Collins, Rory, Ridker, Paul, Thompson, A., Lawlor, D.A., Woodward, M, Collins, R, Kizer, J.R., Sattar, N., Lawlor, Debbie A, Sarwar, N., Ingelsson, Erik,, Davey Smith, George, Danesh, John, Stehouwer, Coen, Ridker, P., The Emerging Risk Factors Collaboration,, Di Angelantonio, Emanuele, Wood, A.M., Whitlock, G., Di Angelantonio, E., Sattar, Naveed, Lawlor, Debbie A., Collins, R., Di Angelantonio, E, Kizer, JR, Whitlock, Gary, Thompson, SG, Nordestgaard, Børge G, Stevens, J, Wormser, David, Stevens, J., Thompson, Simon G., Di Angeloantonio, Emanuele, Emerging Risk Factors Collaboration (Döring, A. ; Meisinger, C.)   +77 more
core   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

Clinical indices and anthropometric measures for magnetic resonance imaging-defined visceral adiposity across the hypercortisolism spectrum

Frontiers in Endocrinology
ObjectiveConventional anthropometric measures may inadequately capture metabolically relevant fat redistribution in hypercortisolism. We evaluated the discriminative performance of clinical indices (Hepatic Steatosis Index [HSI], Visceral Adiposity Index
Aslihan Pekmezci, Mehmet Ali Arikan, Idris Kuzu, Merve Korkmaz Yilmaz, Ceyda Ceren Arikan, Sebnem Burhan, Rukiye Dilara Uzman Tekin, Didem Acarer Bugun, Aytul Hande Yardimci, Mutlu Niyazoglu, Mutlu Niyazoglu, Esra Hatipoglu, Esra Hatipoglu   +12 more
doaj   +1 more source

Obesity Subtypes and Longitudinal Trajectories of Function Over Seven Years of Follow‐Up: Data From the Multicenter Osteoarthritis Study

Arthritis Care &Research, EarlyView.
Objective Obesity, defined by body mass index (BMI) ≥30 kg/m2, is a risk factor for functional limitations in people with knee osteoarthritis (OA). However, function varies among such individuals. Our objective was to evaluate the implications of obesity subtypes on longitudinal patterns of physical functioning in people with or at risk for knee OA ...
Kristine Godziuk, Sarah Tilley, Michael LaValley, Michael C. Nevitt, Cora E. Lewis, James C. Torner, Tuhina Neogi, for the Multicenter Osteoarthritis Study Group   +7 more
wiley   +1 more source

Intelligent Orthopedics: Machine Learning in Diagnosis of Bone Disease, Implants, and Bone Health Monitoring

Advanced Healthcare Materials, EarlyView.
Efficient recovery from traumatic or degenerative diseases is a great challenge, even after all the advancements in bone and cartilage regeneration. Machine learning (ML) algorithms have presented opportunities to enhance these aspects by accurately analyzing imaging data.
Maryam Kamaei, Hesam Mohammadi, Shamim Golafshan, Mojtaba Alehosseini, Mahsa Mohammadzadeh, Atefeh Golshirazi, Nasim Golafshan, Tatiane Eufrásio‐da‐Silva, Alireza Dolatshahi‐Pirouz, Gorka Orive   +9 more
wiley   +1 more source

Cardiometabolic index predicts postoperative atrial fibrillation after isolated CABG: ROC-based comparison with BMI and visceral adiposity indices

Biomolecules & Biomedicine
The assessment of visceral adipose tissue activity has gained significance in cardiac risk stratification. This study evaluates the predictive performance of novel visceral adiposity indices in determining the risk of postoperative atrial fibrillation ...
Ercan Kahraman, Şirin Cetin
doaj   +1 more source

The visceral adiposity index is associated with insulin sensitivity and IGF-I levels in adults with growth hormone deficiency [PDF]

, 2017
The visceral adiposity index, based on anthropometric and metabolic parameters, has been shown to be related to adipose tissue function and insulin sensitivity.
CIRESI, Alessandro, GIORDANO, Carla, GUARNOTTA, Valentina, Radellini S   +3 more
core   +1 more source