Results 81 to 90 of about 3,777,037 (252)

The association of visceral adiposity with cardiovascular events in patients with peripheral artery disease [PDF]

, 2013
Background: Previous studies have suggested that patients with peripheral artery disease (PAD) suffer from a high incidence of cardiovascular events (CVE). Visceral adiposity has been implicated in promoting CVEs.
Vikram Iyer, Buttner Petra, Bradshaw Barbara, Golledge, Jonathan, Walker, Philip J., Barbara Bradshaw (502847), Walker, Philip J, Petra Buttner (347925), Cunningham Margaret, Bradshaw, Barbara, Oliver Cronin, Margaret Cunningham, Petra Buttner, Margaret Cunningham (502849), Iyer Vikram, Philip J Walker, Jonathan Golledge, Walker Philip J., Jonathan Golledge (162150), Oliver Cronin (502846), Philip J. Walker (502850), Cronin Oliver, Cunningham, Margaret, Vikram Iyer (502848), Golledge Jonathan, Barbara Bradshaw, Cronin, Oliver, Buttner, Petra, Iyer, Vikram   +28 more
core   +2 more sources

Degrading GPX4 via Biomimetic Nanoparticle‐Mediated In Situ Synthesis of Deep‐Learning‐Designed Binder‐Degron Chimeras for Prostate Cancer Therapy

Advanced Science, EarlyView.
A deep‐learning‐designed binder is fused to a combinatorial degron to create a binder‐degron chimera (bdC) that recruits the CUL2‐RING ubiquitin ligase complex. Encapsulation in a prostate‐cancer‐targeted, CD47‐camouflaged nanocarrier enables tumor‐specific in situ bdC expression, triggering GPX4 degradation and ferroptosis, thereby establishing a ...
Si‐Han Zhang, Ye An, Na Zeng, Mei‐Cheng Liu, Jian‐Xuan Sun, Xi Gong, Jin‐Zhou Xu, Shao‐Gang Wang, Qi‐Dong Xia   +8 more
wiley   +1 more source

Sex-Specific Misclassification of Obesity When Using Body Mass Index in Young Healthcare Professionals: A Large Cross-Sectional Study Using Multiple Adiposity Indices

Medical Sciences
Background: Body mass index (BMI) remains the standard tool for obesity screening; however, it does not account for body fat distribution or visceral adiposity, potentially leading to clinically relevant misclassification—particularly in young adults ...
Alberto Ramirez Gallegos, Pedro Juan Tárraga López, Mónica Silu Piña Dabreu, Lluis Rodas Cañellas, Ángel Arturo López-González, José Ignacio Ramírez-Manent   +5 more
doaj   +1 more source

A Biomimetic cRGDyk‐Engineered Platelet Nanoplatform for ACAD11 Delivery to Trigger Pyroptosis in Hepatocellular Carcinoma

Advanced Science, EarlyView.
A biomimetic platelet nanoplatform (OE‐ACAD11@R‐PLT) is developed for targeted hepatocellular carcinoma immunotherapy. By selectively delivering therapeutic plasmids, this system induces mitochondrial dysfunction and triggers robust NLRP3/Caspase‐1/GSDMD‐mediated pyroptosis in tumor cells.
Hongyi Bao, Wei Feng, Wei Zong, Yi Li, Xinyue Qin, Xinyue Wang, Yubo Yang, Guanhua Chen, Yiting Hou, Xuan Tan, Lin Chen, Ming Zhang, Feng Wang   +12 more
wiley   +1 more source

Video and Text‐Based Supplemental Health Information and Consumer Willingness to Pay for Nutrient‐Enhanced Eggs

Agribusiness, EarlyView.
ABSTRACT Nutritional information is very important in the food choices of consumers. However, when they are too scientific or technical, they have the potential to confuse consumers, resulting in information asymmetry and dissuading them from making beneficial choices.
Edeoba W. Edobor, Michael J. Best, Anita R. Best, Ondulla T. Toomer   +3 more
wiley   +1 more source

Predictive performance of the visceral adiposity index for a visceral adiposity-related risk: Type 2 Diabetes

Lipids in Health and Disease, 2011
Background Visceral adiposity index (VAI) has recently been developed based on waist circumference, body mass index (BMI), triglycerides (TGs), and high-density lipoprotein cholesterol (HDL-C). We examined predictive performances for incident diabetes of
Azizi Fereidoun, Hadaegh Farzad, Bozorgmanesh Mohammadreza   +2 more
doaj   +1 more source

Preprint: Challenging the visceral fat paradigm: abdominal subcutaneous adiposity dominates cardiometabolic risk in young, lean Indians

Background: Central obesity has been associated with cardiometabolic diseases. Unlike in the white Caucasians, the abdominal subcutaneous adiposity has been associated with higher cardiometabolic risk in Indians.
Rucha S.H. Wagh, Rupali U. Bawdekar, Caroline H.D. Fall, Chittaranjan S. Yajnik, Rashmi B. Prasad, Jimmy D. Bell, E. Louise Thomas, Satyajeet P. Khare, Wareed Alenaini   +8 more
core   +1 more source

The relationship between visceral adiposity index and blood pressure levels in females.

, 2016
The relationship between visceral adiposity index and blood pressure levels in females.
Qingshan Qu (502928), Wenjie Han (1812673), Yanxuan Zhang (2214259), Hengliang Liu (2214256), Yanan Ding (2214262), Dongfeng Gu (216367)   +5 more
core   +1 more source

Automating AI Discovery for Biomedicine Through Knowledge Graphs and Large Language Models Agents

Advanced Intelligent Discovery, EarlyView.
This work proposes a novel framework that automates biomedical discovery by integrating knowledge graphs with multiagent large language models. A biologically aligned graph exploration strategy identifies hidden pathways between biomedical entities, and specialized agents use this pathway to iteratively design AI predictors and wet‐lab validation ...
Naafey Aamer, Muhammad Nabeel Asim, Shan Munir, Andreas Dengel   +3 more
wiley   +1 more source

Diet, visceral adiposity, and impaired lung function in postmenopausal women: a mediation analysis

European Journal of Medical Research
Background Preserved Ratio Impaired Spirometry (PRISm) is a high-risk respiratory phenotype whose pathophysiology in postmenopausal women remains poorly understood.
Hao Sun, Lei Zhao, Qianfei Wang
doaj   +1 more source